Home > Name List By 4 > 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one Canada

CAS No 90729-43-4 , 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one Search by region : Canada

  • Name: 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one
  • Synonyms: Ebastinum [Latin]; Ebastina [Spanish]; Estivan; LAS W-090; Ebastin; Kestine; NCGC00164603-01;Ebastel; 90729-43-4;4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one;
  • CAS Registry Number:
  • Melting Point: 80-82 ºC
  • Density: 1.09 g/cm3
  • Refractive index: 1.59
  • Water Solubility: Practically insoluble in water, very soluble in methylene chloride, slightly soluble in methanol
  • Molecular Weight: 469.65756
  • InchiKey: MJJALKDDGIKVBE-UHFFFAOYSA-N
  • InChI: InChI=1S/C32H39NO2/c1-32(2,
    3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-
    6-4-7-12-26)27-13-8-5-9-14-27/h4-9,11-14,16-19,29,31H,10,15,20-24H2,
    1-3H3
  • Molecular Formula: C32H39NO2
  • Molecular Structure:CAS No:90729-43-4 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one

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90729-43-4 EBASTINE

  • Canada TLC PharmaChem., Inc. [Manufacturer]
  • Tel: 905-760-1098
  • Fax: 905-760-2098
  • Address: TLC PharmaChem., Inc.
    5-150 Connie Crescent
    Concord, Ontario
    L4K 1L9, Canada null,nullCanada
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90729-43-4 EBASTINE

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
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    H4P 2R2 null,nullCanada
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References of 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one
Title: Ebastine
CAS Registry Number: 90729-43-4
CAS Name: 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone
Synonyms: 4￠-tert-butyl-4-[4-(diphenylmethoxy)piperidino]butyrophenone; 4-diphenylmethoxy-1-[3-(4-tert-butylbenzoyl)propyl]piperidine
Manufacturers' Codes: LAS-W-090
Trademarks: Ebastel (Almirall); Estivan (Almirall); Evastel (Almirall); Kestin (Almirall); Kestine (Almirall)
Molecular Formula: C32H39NO2
Molecular Weight: 469.66
Percent Composition: C 81.83%, H 8.37%, N 2.98%, O 6.81%
Literature References: Nonsedating type histamine H1-receptor antagonist. Prepn: J. M. P. Soto et al., EP 134124; eidem, US 4550116 (both 1985 to Fordonal). Metabolized in vivo to carebastine, its active carboxylic acid metabolite. Clinical pharmacology, pharmacokinetics: J. Vincent et al., Br. J. Clin. Pharmacol. 26, 497 (1988). Effect on psychomotor performance: J. Vincent et al., ibid. 503.
 
Derivative Type: Fumarate
Molecular Formula: C32H39NO2.C4H4O4
Molecular Weight: 585.73
Percent Composition: C 73.82%, H 7.40%, N 2.39%, O 16.39%
Properties: Crystals from ethanol, mp 197-198°.
Melting point: mp 197-198°
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic.