CAS No 90729-43-4 , 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one Search by region : India

Name: 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one
Synonyms: Ebastinum [Latin]; Ebastina [Spanish]; Estivan; LAS W-090; Ebastin; Kestine; NCGC00164603-01;Ebastel; 90729-43-4;4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one;
CAS Registry Number:90729-43-4
Melting Point: 80-82 ºC
Density: 1.09 g/cm³
Refractive index: 1.59
Water Solubility: Practically insoluble in water, very soluble in methylene chloride, slightly soluble in methanol
Molecular Weight: 469.65756
InchiKey: MJJALKDDGIKVBE-UHFFFAOYSA-N
InChI: InChI=1S/C32H39NO2/c1-32(2,
3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-
6-4-7-12-26)27-13-8-5-9-14-27/h4-9,11-14,16-19,29,31H,10,15,20-24H2,
1-3H3
Molecular Formula: C₃₂H₃₉NO₂
Molecular Structure:

Related products

Select to

          
           90729-43-4 EBASTINE 
           
             JAI RADHE SALES
             
              null
Fax: 0091-79-26569884
Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT  , INDIA. null,nullIndia

           90729-43-4 Ebastine
           
             Shreeji Pharma International
             
              [Manufacturers]
Tel: +91-265-3019110
Fax: +91-265-2465036
Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia

           90729-43-4 Ebastine
           Ebastine, With EDMF Available
 
             J.INC. 
             
              [Manufacturer]
Tel: +91 79 30071152, 30071190, 30071175, 30071153 
Fax: +91 79 30071176, 26574630  
Address: # 95, Rangwala Towers, Law garden,
Ellisbridge, Ahmedabad 380006,
Gujarat State, India.
380006  AhmedabadINDIA Ahmedabad,nullIndia

Select to

1/1

References of 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one

Title: Ebastine
CAS Registry Number: 90729-43-4
CAS Name: 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone
Synonyms: 4￠-tert-butyl-4-[4-(diphenylmethoxy)piperidino]butyrophenone; 4-diphenylmethoxy-1-[3-(4-tert-butylbenzoyl)propyl]piperidine
Manufacturers' Codes: LAS-W-090
Trademarks: Ebastel (Almirall); Estivan (Almirall); Evastel (Almirall); Kestin (Almirall); Kestine (Almirall)
Molecular Formula: C32H39NO2
Molecular Weight: 469.66
Percent Composition: C 81.83%, H 8.37%, N 2.98%, O 6.81%
Literature References: Nonsedating type histamine H1-receptor antagonist. Prepn: J. M. P. Soto et al., EP 134124; eidem, US 4550116 (both 1985 to Fordonal). Metabolized in vivo to carebastine, its active carboxylic acid metabolite. Clinical pharmacology, pharmacokinetics: J. Vincent et al., Br. J. Clin. Pharmacol. 26, 497 (1988). Effect on psychomotor performance: J. Vincent et al., ibid. 503.

Derivative Type: Fumarate
Molecular Formula: C32H39NO2.C4H4O4
Molecular Weight: 585.73
Percent Composition: C 73.82%, H 7.40%, N 2.39%, O 16.39%
Properties: Crystals from ethanol, mp 197-198°.
Melting point: mp 197-198°

Therap-Cat: Antihistaminic.
Keywords: Antihistaminic.