Title: Diminazene Aceturate
CAS Registry Number: 908-54-3
CAS Name: N-Acetylglycine compd with 4,4￠-(1-triazene-1,3-diyl)bis(benzenecarboximidamide) (2:1)
Synonyms: N-acetylglycine compd with 4,4￠-(diazoamino)dibenzamidine; diminazene diaceturate; 4,4￠-(diazoamino)dibenzamidine diaceturate; 1,3-bis(
p-amidinophenyl)triazene bis(
N-acetylglycinate); 1,3-bis[4-guanylphenyl]triazene diaceturate; 4,4￠-diamidinodiazoaminobenzene diaceturate;
p,p￠-diguanyldiazoaminobenzene diaceturate
Trademarks: Berenil (Intervet)
Molecular Formula: C22H29N9O6
Molecular Weight: 515.52
Percent Composition: C 51.26%, H 5.67%, N 24.45%, O 18.62%
Literature References: Prepn: Brodersen
et al., US 2838485 (1958 to Hoechst); Stavrovskaya, Drusvyatskaya,
C.A. 59, 15199a (1963). Mode of action: Festy
et al., C.R. Seances Acad. Sci. Ser. D 271, 730 (1970). Chemotherapeutic characteristics: Schmulevich
et al., Veterinariya (Moscow) 38, 23 (1961),
C.A. 56, 13512b (1962).
Review: Newton in
Antibiotics vol. 3, J. W. Corcoran, F. E. Hahn, Eds. (Springer-Verlag, New York, 1975) pp 34-47.
Properties: Yellow solid, dec 217°. Sol in 14 parts water (20°); slightly sol in alcohol; very slightly sol in ether, chloroform.
Therap-Cat-Vet: Antiprotozoal (Trypanosoma, Babesia).
