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CAS No 91-75-8 , N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline

  • Name: N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
  • Synonyms: Antistine; Phenazolin; Antihistal;Antasten; Antastan; Phenazoline; Histostab; Antistin;N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline; Imidamine;
  • CAS Registry Number:
  • Melting Point: 159
  • Boiling Point: 210 - 220 (0.7 torr)
  • Density: 1.188 g/cm3
  • Safety Statements: Poison by ingestion, subcutaneous, and intraperitoneal routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 202-094-0
  • Molecular Weight: 265.35286
  • InchiKey: REYFJDPCWQRWAA-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-
    10-16/h1-10H,11-14H2,(H,18,19)
  • Molecular Formula: C17H19N3
  • Molecular Structure:CAS No:91-75-8 N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
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91-75-8 Antazoline

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91-75-8 Antazoline

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91-75-8 1H-Imidazole-2-methanamine,4,5-dihydro-N-phenyl-N-(phenylmethyl)-

  • China Wuhan Yuancheng [Manufacturers]
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91-75-8 Antazoline

  • Antazoline, 98
  • China stone_zm@topharman.com [Manufacturer]
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91-75-8 Antazoline Hydrochloride

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91-75-8 ANTAZOLINE

  • United States SST Corporation [Manufacturer]
  • Tel: 800-222-0921/ 973-473-4300
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  • Address: SST Corporation
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91-75-8 Antazoline hydrochloride

  • Antazoline hydrochloride
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
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References of N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
Title: Antazoline
CAS Registry Number: 91-75-8
CAS Name: 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine
Synonyms: 2-(N-benzylanilinomethyl)-2-imidazoline; phenazoline; 2-(N-phenyl-N-benzylaminomethyl)imidazoline; imidamine
Manufacturers' Codes: 5512-M
Molecular Formula: C17H19N3
Molecular Weight: 265.35
Percent Composition: C 76.95%, H 7.22%, N 15.84%
Literature References: Prepn: Miescher, Klarer, US 2449241 (1948 to Ciba). HPLC determn in ophthalmic solutions: S. C. Ruckmick et al., J. Pharm. Sci. 84, 502 (1995). Clinical trial in combination with naphazoline in allergic conjunctivitis: M. B. Abelson et al., Arch. Ophthalmol. 108, 520 (1990).
Properties: Crystals, mp 120-122°.
Melting point: mp 120-122°
 
Derivative Type: Hydrochloride
CAS Registry Number: 2508-72-7
Trademarks: Antistine (Novartis); Antasten (Novartis)
Molecular Formula: C17H19N3.HCl
Molecular Weight: 301.81
Percent Composition: C 67.65%, H 6.68%, N 13.92%, Cl 11.75%
Properties: Bitter crystals producing temporary numbness of the tongue. mp 237-241°. uv max: 242 nm (E1%1cm 495 to 515); min 222 nm. One gram dissolves in 40 ml water, in 25 ml alc. Practically insol in ether, benzene, chloroform. pH (1% aq soln): 6.3.
Melting point: mp 237-241°
Absorption maximum: uv max: 242 nm (E1%1cm 495 to 515)
 
Derivative Type: Phosphate
CAS Registry Number: 154-68-7
Molecular Formula: C17H19N3.H3PO4
Molecular Weight: 363.35
Percent Composition: C 56.19%, H 6.10%, N 11.56%, P 8.52%, O 17.61%
Properties: Crystals. Bitter taste. mp 194-198°. Sol in water. Sparingly sol in methanol. Practically insol in benzene, ether. pH (2% aq soln): 4.5.
Melting point: mp 194-198°
 
Therap-Cat: Antihistaminic.
Therap-Cat-Vet: Antihistaminic.
Keywords: Antihistaminic.