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CAS No 968-81-0 , 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea Search by region : India

  • Name: 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
  • Synonyms: Dimelin; Dimelor; Metaglucina;1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea; Hypoglicil; Acetohexamid; Ordimel; Minoral; Gamadiabet;Dymelor;
  • CAS Registry Number:
  • Density: 1.3g/cm3
  • Refractive index: 1.581
  • Safety Statements: Human reproductive effects by an unspecified route: stillbirth. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx and NOx.
  • EINECS: 213-530-4
  • Molecular Weight: 324.3953
  • InchiKey: VGZSUPCWNCWDAN-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H20N2O4S/c1-11(18)12-7-9-14(10-8-12)22(20,
    21)17-15(19)16-13-5-3-2-4-6-13/h7-10,13H,2-6H2,1H3,(H2,16,17,19)
  • Molecular Formula: C15H20N2O4S
  • Molecular Structure:CAS No:968-81-0 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea

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968-81-0 Acetohexamide

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References of 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
Title: Acetohexamide
CAS Registry Number: 968-81-0
CAS Name: 4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide
Synonyms: 1-[(p-acetylphenyl)sulfonyl]-3-cyclohexylurea; 3-cyclohexyl-1-(p-acetylphenylsulfonyl)urea; N-(p-acetylbenzenesulfonyl)-N￠-cyclohexylurea; cyclamide; tsiklamid
Trademarks: Dimelor (Lilly); Dymelor (Lilly); Dimeline (Shionogi); Ordimel (Lilly)
Molecular Formula: C15H20N2O4S
Molecular Weight: 324.40
Percent Composition: C 55.54%, H 6.21%, N 8.64%, O 19.73%, S 9.88%
Literature References: Prepn: GB 912789 (1962 to Lilly); Marshall et al., J. Med. Chem. 6, 60 (1963). Comprehensive description: C. E. Shafer, Anal. Profiles Drug Subs. 1, 1-14 (1972); A. A. Al-Badr, H. A. El-Obeid, Anal. Profiles Drug Subs. Excip. 21, 1-41 (1992).
Properties: Crystals from 90% aq ethanol, mp 188-190° (GB 912789); from dil ethanol, mp 175-177° (Marshall). uv max (methanol): 247, 283 nm. Sol in pyridine; slightly sol in alcohol, chloroform. Insol in water, ether.
Melting point: mp 188-190° (GB 912789); mp 175-177° (Marshall)
Absorption maximum: uv max (methanol): 247, 283 nm
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Sulfonylurea Derivatives.