Home > Name List By other > [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1, 3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate

CAS No 97240-79-4 , [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,
3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate

  • Name: [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,
    3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate
  • Synonyms: Topina; Tipiramato [Spanish]; Tipiramate [French]; Epitomax;[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,
    3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate; Topamax Sprinkle; Topimax; McN-4853;Topamax; Topomax;
  • CAS Registry Number:
  • Melting Point: 125 ºC
  • Density: 1.336 g/cm3
  • Refractive index: 1.497
  • Water Solubility: DMSO Solubility : ~44 mg/mL
  • Safety Statements: 26-36
  • Hazard Symbols: Xn: Harmful;
  • Molecular Weight: 339.36204
  • InchiKey: KJADKKWYZYXHBB-XBWDGYHZSA-N
  • InChI: InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,
    14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,
    8-,9+,12+/m1/s1
  • Risk Statements: 36/37/38
  • Molecular Formula: C12H21NO8S
  • Molecular Structure:CAS No:97240-79-4 [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,<br />3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate

Related products

Search by region :

Select to

97240-79-4 topiramate

  • China Xin xing Chemical Co.,LTD [Manufacturers]
  • Tel: 86-516-88957771
  • Fax: 86-516-88957771
  • Address: No79 # Xin bei Rd Xin yi city Jiang su Province China Xin yi,JiangsuChina
Contact Supplier

97240-79-4 topiramate

  • China Taizhou Volsen Chemical Co Ltd [Manufacturer, Trading Company]
  • Tel: 86-576-88869393
  • Fax: 86-576 88869392
  • Address: 1721-1722, Floor 17, Block A, Junyue Building, Jiaojiang District Taizhou,ZhejiangChina
Contact Supplier

97240-79-4 TOPIRATMATE

  • China Xian terra biochem Co.,Ltd [Manufacturer]
  • Tel: +86-29-88315623
  • Fax: +86-29-88317883
  • Address: S711, Innovation Bldg No.25 Gaoxin 1st Rd,
    Xian P.R of China 710075 null,nullChina
Contact Supplier

97240-79-4 Topiramate

Contact Supplier

97240-79-4 topiramate

  • China Green Pharmaceutical Ltd. [Manufacturers]
  • Tel: +86-531-62302076
  • Fax: +86-531-62302096
  • Address: Keda road,Malinggang industry park, Mudan district, Heze, Shandong, China. Heze,Shandong provinceChina
Contact Supplier

97240-79-4 Topiramate

  • China Shanghai Chely Co. Ltd. [Manufacturers]
  • Tel: 021- 68885110
  • Fax: 021-58829203
  • Address: #603，Block7，Rongcheng Garden，#9 Rongcheng, Pudong, Shanghai 200120, shanghai,shanghaiChina
Contact Supplier

97240-79-4 Topiramate

Contact Supplier

97240-79-4 topiramate

  • China Xi'An ShengFang chemical [Manufacturers]
  • Tel: +86-029-83793007 +86-0136-79253776
  • Fax: 029-86169296
  • Address: wei yang road 66# xi'an,shaanxiChina
Contact Supplier

97240-79-4 topiramate

Contact Supplier

97240-79-4 topiramate

  • China Xi'an Terra Biochem Co. Ltd. [Manufacturers]
  • Tel: 0086-29-88315623
  • Fax: 0086-29-88317883
  • Address: S711, Innovation Bldg No.25 Gaoxin 1st Rd, Xian P.R of China 710075 Xi'an,shanxiChina
Contact Supplier

Select to

9/11
Previous 2 3 4 5 6 7 8 9 10 11 Next
References of [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,
3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate
Title: Topiramate
CAS Registry Number: 97240-79-4
CAS Name: 2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fructopyranose sulfamate
Synonyms: 2,3:4,5-di-O-isopropylidene-b-D-fructopyranose sulfamate
Manufacturers' Codes: McN-4853; RWJ-17021-000
Trademarks: Topamax (J & J)
Molecular Formula: C12H21NO8S
Molecular Weight: 339.36
Percent Composition: C 42.47%, H 6.24%, N 4.13%, O 37.72%, S 9.45%
Literature References: Sulfamate substituted monosaccharide; structurally distinct antiepileptic agent. Prepn: B. E. Maryanoff, J. F. Gardocki, US 4513006 (1985 to McNeil); and anticonvulsant activity: B. E. Maryanoff et al., J. Med. Chem. 30, 880 (1987). GC determn in plasma: M. L. Holland et al., J. Chromatogr. 433, 276 (1988). Comparative pharmacokinetics: M. Bialer, Clin. Pharmacokinet. 24, 441 (1993). Series of articles on pharmacology and clinical experience in epilepsy: Epilepsia 38, Suppl. 1, 1-62 (1997). Review of clinical trials in migraine prevention: G. Bussone et al., Int. J. Clin. Pract. 59, 961-968 (2005); of pharmacology and clinical experience: S. D. Silberstein et al., Clin. Ther. 27, 154-165 (2005).
Properties: Crystals from ethyl acetate + hexane, mp 125-126°. [a]D23 -34.0° (c = 0.4 in methanol).
Melting point: mp 125-126°
Optical Rotation: [a]D23 -34.0° (c = 0.4 in methanol)
Therap-Cat: Anticonvulsant; antimigraine.
Keywords: Anticonvulsant; Antimigraine.