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CAS No 976-71-6 , Canrenone

  • Name: Canrenone
  • Synonyms: Canrenone;17-hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid gamma-lactone;-;
  • CAS Registry Number:
  • Melting Point: 158-1600C
  • Flash Point: 237.6°C
  • Boiling Point: 541.1°Cat760mmHg
  • Density: 1.19g/cm3
  • Refractive index: 1.581
  • Flash Point: 237.6°C
  • EINECS: 213-554-5
  • Molecular Weight: 340.46
  • InChI: InChI=1/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/m1/s1
  • Molecular Formula: C22H28O3
  • Molecular Structure:CAS No:976-71-6 Canrenone

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References of Canrenone
Title: Canrenone
CAS Registry Number: 976-71-6
CAS Name: (17a)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid g-lactone
Synonyms: 17a-(2-carboxyethyl)-17b-hydroxyandrosta-4,6-dien-3-one lactone; 17a-(2-carboxyethyl)-17b-hydroxy-3-oxoandrosta-4,6-diene lactone; 6-dehydrotestosterone-17a-propionic acid g-lactone; 3-(3-oxo-17b-hydroxy-4,6-androstadien-17a-yl)propionic acid g-lactone
Trademarks: Phanurane (Specia)
Molecular Formula: C22H28O3
Molecular Weight: 340.46
Percent Composition: C 77.61%, H 8.29%, O 14.10%
Literature References: Aldosterone antagonist. Prepd by dehydrogenation of 17-hydroxy-3-oxo-17a-pregn-4-ene-21-carboxylic acid g-lactone: Cella, Tweit, J. Org. Chem. 24, 1109 (1959); Cella, US 2900383 (1959 to Searle).
Properties: Crystals from ethyl acetate, mp 149-151°, solidifies and remelts at 165°. [a]D +24.5° (chloroform). uv max: 283 nm (e 26700).
Melting point: mp 149-151°, solidifies and remelts at 165°
Optical Rotation: [a]D +24.5° (chloroform)
Absorption maximum: uv max: 283 nm (e 26700)
 
Derivative Type: Free acid potassium salt
CAS Registry Number: 2181-04-6
Synonyms: Potassium canrenoate
Trademarks: Kanrenol (SPA); Soldactone (Searle); Venactone (Lepetit)
Molecular Formula: C22H29KO4
Molecular Weight: 396.56
Percent Composition: C 66.63%, H 7.37%, K 9.86%, O 16.14%
 
Therap-Cat: Diuretic.
Keywords: Aldosterone Antagonist; Diuretic; Steroids.