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CAS No 98224-03-4 , 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine Search by region : Germany

  • Name: 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine
  • Synonyms: 98224-03-4;hydrochloride; 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride;Eltoprazine hydrochloride;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine; SBB056114;
  • CAS Registry Number:
  • Flash Point: 186.2°C
  • Boiling Point: 384.3°Cat760mmHg
  • Density: 1.18g/cm3
  • Flash Point: 186.2°C
  • Molecular Weight: 256.72858
  • InchiKey: JFSOSUNPIXJCIX-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;
    /h1-3,13H,4-9H2;1H
  • Molecular Formula: C12H17ClN2O2
  • Molecular Structure:CAS No:98224-03-4 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine

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98224-03-4 Eltoprazinehydrochloride

  • Eltoprazinehydrochloride
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine
Title: Eltoprazine
CAS Registry Number: 98224-03-4
CAS Name: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine
Synonyms: 1-(1,4-benzodioxan-5-yl)piperazine
Molecular Formula: C12H16N2O2
Molecular Weight: 220.27
Percent Composition: C 65.43%, H 7.32%, N 12.72%, O 14.53%
Literature References: Selective serotonin 5HT1 agonist; psychotropic agent with antiagressive activity. Prepn: J. Hartog et al., EP 138280; idem et al., EP 189612 (1985, 1986 both to Duphar). Prepd (not claimed): idem et al., US 4833142 (1989 to Duphar). Crystal structure: M. L. Verdonk et al., Acta Crystallogr. C48, 2271 (1992). Series of articles on pharmacology, receptor binding and mechanism of action: Drug Metab. Drug Interact. 8, 1-186 (1990). Pharmacokinetics: M. H. de Vries et al., Eur. J. Clin. Pharmacol. 41, 485 (1991). Clinical evaluation in self-injury: W. M. A. Verhoeven et al., Lancet 340, 1037 (1992); in violent psychiatric patients: J. Tiihonen et al., ibid. 341, 307 (1993).
 
Derivative Type: Hydrochloride
CAS Registry Number: 98206-09-8
Manufacturers' Codes: DU-28853
Molecular Formula: C12H16N2O2.HCl
Molecular Weight: 256.73
Percent Composition: C 56.14%, H 6.67%, N 10.91%, O 12.46%, Cl 13.81%
Properties: Crystals from ethanol, mp 256-258°. Soly in water: 19 g/100 ml.
Melting point: mp 256-258°
 
Therap-Cat: Serenic.
Keywords: Serenic; Serotonin Receptor Agonist.