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  • SQ 22536 17318-31-9

    • Cell-permeable. A selective, ATP-competitive inhibitor of Aurora B kinase in vitro (IC 50 values are 50 nM, 250 nM and 1 μM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC 50 > 10 μM)...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    BCl-2 Inhibitor GX15-070 803712-67-6

    • Cell-permeable. A small molecule pan-Bcl-2 antagonist that mimics BH3-only proteins by binding to multiple antiapoptotic Bcl-2 members. GX15-070 has been shown to overcome Bcl-2-, Bcl-xl–, Bcl-w–, and Mcl-1–mediated resistance to Bax or Bak. It po...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    Pepstatin A 26305-03-3

    • An inhibitor of acid proteases (aspartyl peptidases), e.g. pepsin, rennin, and cathepsin D. The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine proteases . More information please visit the website: ht...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    Plumbagin 481-42-5

    • A quinonoid constituent isolated from the root of Plumbago zeylanica. Displays anticarcinogenic, antiatherosclerotic, and antimicrobial effects as well as anticancer and antiproliferation properties in a variety of cell lines and animal models. Induc...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    Lactacystin (Synthetic) 133343-34-7

    • Cell-permeable. A potent and selective inhibitor of the 20 S proteasome. Binds irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activi...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    Pellitorine 18836-52-7

    • Cell-permeable. A natural product isolated from the roots of Piper Nigrum. Modulator of the sensory neuron function to induce tingling parethesia. Excellent stable model compound for sensory studies. α-Glucosidase inhibitor used in diabetes mellitus...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    Terpendole C 156967-65-6

    • Isolated from Albophoma yamanashiensis. An acyl-CoA:cholesterol acyltransferase (ACAT) isozymes ACAT1 and ACAT2 inhibitor. Also acts as a tremorgen and cholesteryl ester (CE) synthesis inhibitor. More information please visit the website: http://www....
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
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    Oleanolic Acid 508-02-1

    • Oleanolic acid(Caryophyllin) is a naturally occurring triterpenoid, widely distributed in food and medicinal plants, related to betulinic acid. It is relatively non-toxic, antitumor, and hepatoprotective, as well as exhibiting antiviral properties. A...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    Torsemide(Demadex) 56211-40-6

    • Torsemide(Demadex) is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 uM. Furosemide is the most widely prescribed loop diuretic in the setting of systolic heart failure (HF), yet torsemide has been shown to have less inter- and intra...
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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    BIBR-1048 (Dabigatran) 211915-06-9

    • BIBR-1048 (Dabigatran) is an anticoagulant from the class of the direct thrombin inhibitors. More information please visit the website: http://www.creative-enzymes.com/product/BIBR1048-Dabigatran-_2348.html
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    • United States Creative Enzymes [Manufacturer]
    • Tel: 1-631-6197922
    • Fax: 1-631-9388127
    • Address: Shirley New York,New YorkUnited States
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