Home > Name List By r > Rufloxacin

CAS No 101363-10-4 , Rufloxacin

  • Name: Rufloxacin
  • Synonyms: Rufloxacino;101363-10-4;Rufloxacin; Rufloxacinum; MF 934; RUFLOXACIN HCl; Rufloxacine;
  • CAS Registry Number:
  • Density: 1.54
  • Molecular Weight: 363.406523
  • InchiKey: NJCJBUHJQLFDSW-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H18FN3O3S/c1-19-2-4-20(5-3-19)14-12(18)8-10-13-16(14)25-7-6-
    21(13)9-11(15(10)22)17(23)24/h8-9H,2-7H2,1H3,(H,23,24)
  • Molecular Formula: C17H18FN3O3S
  • Molecular Structure:CAS No:101363-10-4 Rufloxacin

Related products

Search by region :

Select to

101363-10-4 7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-

  • United Kingdom Zerenex Molecular Limited [Manufacturers]
  • Tel: +44 (0) 1204 527 700
  • Fax: 44 (0) 1204 527700
  • Address: UNITED KINGDOM null,nullUnited Kingdom
Contact Supplier

101363-10-4 Rufloxacin

Contact Supplier

101363-10-4 7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-

Contact Supplier

101363-10-4 RUFLOXACIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of Rufloxacin
Title: Rufloxacin
CAS Registry Number: 101363-10-4
CAS Name: 9-Fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid
Manufacturers' Codes: MF-934
Molecular Formula: C17H18FN3O3S
Molecular Weight: 363.41
Percent Composition: C 56.18%, H 4.99%, F 5.23%, N 11.56%, O 13.21%, S 8.82%
Literature References: Fluorinated quinolone; structurally similar to ofloxacin, q.v. Prepn: G. Mascellani et al., AU 85 39142; eidem, US 4684647 (1985, 1987 both to Mediolanum); V. Cecchetti et al., J. Med. Chem. 30, 465 (1987). In vitro activity: R. Wise et al., Antimicrob. Agents Chemother. 29, 649 (1992). Mechanism of action and resistance: L. J. V. Piddock et al., J. Antimicrob. Chemother. 31, 855 (1993). Pharmacokinetics and safety: J. C. Kisicki et al., ibid. 36, 1296 (1992). HPLC determn in biological fluids: F. Lombardi et al., J. Chromatogr. 576, 129 (1992). Clinical study in cystitis and urinary tract infections: R. Mattina et al., Infection 21, 106 (1993); in bronchitis: W. Klietmann et al., Antimicrob. Agents Chemother. 37, 2298 (1993).
 
Derivative Type: Hydrochloride
CAS Registry Number: 106017-08-7
Manufacturers' Codes: ISF-09334
Trademarks: Qari (Mediolanum); Monos (SKB); Tebraxin (Bracco)
Molecular Formula: C17H18FN3O3S.HCl
Molecular Weight: 399.87
Percent Composition: C 51.06%, H 4.79%, F 4.75%, N 10.51%, O 12.00%, S 8.02%, Cl 8.87%
Properties: Crystals from ethanol/water, mp 322-324° (Cecchetti). LD50 in rats, mice (mg/kg): 285, 224 i.v.; LD50 in rabbits, male, female rats (mg/kg): 660, 631, 501 orally (Cecchetti).
Melting point: mp 322-324° (Cecchetti)
Toxicity data: LD50 in rats, mice (mg/kg): 285, 224 i.v.; LD50 in rabbits, male, female rats (mg/kg): 660, 631, 501 orally (Cecchetti)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.