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CAS No 10262-69-8 , Maprotiline

  • Name: Maprotiline
  • Synonyms: Maprotilina; Maprotilina [INN-Spanish]; Maprotilin; Maprotylina [Polish];Maprotiline; Maprotilinum;Deprilept; Dibencycladine; Maprotilinum [INN-Latin];
  • CAS Registry Number:
  • Transport: 3249
  • Density: 1.08 g/cm3
  • Refractive index: 1.599
  • Safety Statements: Poison by intravenous route. Moderately toxic by ingestion. Human systemic effects by ingestion: somnolence, coma, and blood pressure elevation. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 233-599-4
  • Molecular Weight: 277.40332
  • InchiKey: QSLMDECMDJKHMQ-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-
    10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3
  • Molecular Formula: C20H23N
  • Molecular Structure:CAS No:10262-69-8 Maprotiline
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10262-69-8 Maprotiline

  • Maprotiline
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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10262-69-8 9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-

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10262-69-8 Maprotiline

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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10262-69-8 Maprotiline

  • Maprotiline
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,China
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10262-69-8 Maprotiline

  • Maprotiline, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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10262-69-8 Maprotiline

  • Maprotiline, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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10262-69-8 Maprotiline

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10262-69-8 9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-

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10262-69-8 Maprotiline

  • Maprotiline, 99%
  • China Tianjin Pharmacn Science Co., Ltd. [Manufacturer]
  • Tel: 86-22-23359620/ 86-13612042162 (mobile)
  • Fax: 86-22-23359620
  • Address: 1006 Sinochem Building, 707 Lianmeng RD, Shijiazhuang 050061, Hebei, China ,China
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10262-69-8 9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-

  • China Beijing Merson Pharmaceutical Co., Ltd [Manufacturers]
  • Tel: 0086-10-80484934 0086-10-80484574/80483447
  • Fax: 0086-10-80485714
  • Address: 2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road ,Shunyi District , Beijing 101318, P.R.China Beijing,BeijingChina
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References of Maprotiline
Title: Maprotiline
CAS Registry Number: 10262-69-8
CAS Name: N-Methyl-9,10-ethanoanthracene-9(10H)-propanamine
Synonyms: 9-(g-methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracene; 1-(3-methylaminopropyl)dibenzo[b,e]bicyclo[2.2.2]octadiene
Molecular Formula: C20H23N
Molecular Weight: 277.40
Percent Composition: C 86.59%, H 8.36%, N 5.05%
Literature References: Prepn: P. Schmidt et al., US 3399201 (1968 to Ciba). Synthesis, NMR, mass spectra: M. Wilhelm, P. Schmidt, Helv. Chim. Acta 52, 1385 (1969). Toxicity: R. Hess et al., Boll. Chim. Farm. 112, 782 (1973), C.A. 81, 33479p (1974). Review of pharmacology and therapeutic efficacy: R. M. Pinder et al., Drugs 13, 321 (1977). Comprehensive description: S. K. Suh, J. B. Smith, Anal. Profiles Drug Subs. 15, 393-426 (1986).
Properties: mp 92-94°.
Melting point: mp 92-94°
 
Derivative Type: Hydrochloride
CAS Registry Number: 10347-81-6
Manufacturers' Codes: Ba-34276
Trademarks: Deprilept (Promonta); Ludiomil (Novartis); Psymion (TAD)
Molecular Formula: C20H23N.HCl
Molecular Weight: 313.86
Percent Composition: C 76.54%, H 7.71%, N 4.46%, Cl 11.30%
Properties: Crystals from isopropanol, mp 230-232°. Freely sol in methanol and chloroform, slightly sol in water. Practically insol in isooctane. LD50 in mice, rats (mg/kg): ~750, ~900 orally (Hess).
Melting point: mp 230-232°
Toxicity data: LD50 in mice, rats (mg/kg): ~750, ~900 orally (Hess)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tetracyclics.