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CAS No 10405-02-4 , Trospium chloride

  • Name: Trospium chloride
  • CAS Registry Number:
  • Transport: OTH
  • EINECS: 233-875-4
  • Molecular Weight: 427.97
  • InChI: InChI=1/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22?,23+;/m0./s1
  • Molecular Formula: C25H30NO3.Cl
  • Molecular Structure:CAS No:10405-02-4 Trospium chloride
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10405-02-4 Trospium chloride

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10405-02-4 TROSPIUM CHLORIDE-D8

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
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    Mumbai-400053, INDIA. ,India
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10405-02-4 TROSIPIUM CHLORIDE

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 ,China
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10405-02-4 TROSPIUM-D8 CHLORIDE

  • United States EJY Tech, Inc. [Manufacturer]
  • Tel: 301-526-7059
  • Fax: 301-561-6521
  • Address: 9430 Key West Avenue
    Suite 220
    Rockville , MD 20850 ,United States
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10405-02-4 TROSPIUM CHLORIDE

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 ,Canada
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10405-02-4 TROSPIUM CHLORIDE INTERMEDIATE

  • China CHANGZHOU WEIJIA CHEMICAL CO.,LTD. [Manufacturer]
  • Tel: +86 519 86805358
  • Fax: +86 519 88836898
  • Address: CHANGZHOU WEIJIA CHEMICAL CO.,LTD.
    RM811, No.517 Jinling Road,Changzhou,
    Jiangsu(213003),China ,China
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10405-02-4 TTOSIPIUM CHLORIDE

  • China Taizhou Creating Chemical Co.,Ltd [Manufacturer]
  • Tel: +86-576-88827176/ +86-576-88820069
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  • Address: B Suite 12F,
    Jiangbin Building,Jiaojiang,Taizhou,
    Zhejiang China ,China
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10405-02-4 LTS00180 TROSPIUM CHLORIDE

  • Hong kong Lotus chemical (HK) Limited [Manufacturer]
  • Tel: +86 23 86092822 (China)/ +852 29738324 (Hong Kong)
  • Fax: +86 23 86092822
  • Address: Lotus Chemical Limited,. (China office)
    Address: 602 Room, 172#, Gaoyan Road, Yubei District, Chongqing, China
    Postcode: 401120 ,Hong kong
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10405-02-4 TROSPIUM CHLORIDE

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
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  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA ,China
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10405-02-4 TROSIPIUM CHLORIDE

  • China Shanghai Everchem Co.,Ltd. [Manufacturer]
  • Tel: +86-21-5192-3949
  • Fax: +86-21-5192-3940
  • Address: No.277 Zheqiao Road,
    Shanghai 201206 China ,China
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References of Trospium chloride
Title: Trospium Chloride
CAS Registry Number: 10405-02-4
CAS Name: (1a,3b,5a)-3-[(Hydroxydiphenylacetyl)oxy]spiro[8-azoniabicyclo[3.2.1]octane-8,1¢-pyrrolidinium] chloride
Synonyms: 3a-hydroxyspiro[1aH,5aH-nortropane-8,1¢-pyrrolidinium] chloride benzilate; azoniaspiro(3a-benziloyloxynortropane-8,1¢-pyrrolidine) chloride; azoniaspiro(3a-diphenylglycoloyloxynortropan-8,1¢-pyrrolidine) chloride; 3a-benziloyloxyspiro(nortropane-8,1¢-pyrrolidinium) chloride
Trademarks: Regurin (Galen); Relaspium (Isei); Sanctura (Indevus); Spasmex (Pfleger); Spasmolyt (Madaus)
Molecular Formula: C25H30ClNO3
Molecular Weight: 427.96
Percent Composition: C 70.16%, H 7.07%, Cl 8.28%, N 3.27%, O 11.22%
Literature References: Tropine derivative with anticholinergic activity. Prepn: NL 6402155; R. Pfleger et al., US 3480626 (1964, 1969 both to Pfleger); H. Bertholdt et al., Arzneim.-Forsch. 17, 719 (1967). Pharmacology and toxicology in animals: H. Antweiler et al., ibid. 16, 1581 (1966). Inhibition of gastric motility and acid secretion in humans: G. Lux, P. Frühmorgen, Fortschr. Med. 96, 2113 (1978). Fluorimetric determn in plasma and urine: G. Schladitz-Keil et al., J. Chromatogr. 345, 99 (1985). Bioavailability: eidem, Arzneim.-Forsch. 36, 984 (1986). Clinical trial in bladder hyper-reflexia: H. Madersbacher et al., Br. J. Urol. 75, 452 (1995). Review in overactive bladder: N. R. Zinner, Expert Opin. Pharmacother. 6, 1409-1420 (2005).
Properties: Crystals from ethanol-ether, mp 255-257° (dec). Soly in water: ~1 g/2 ml. LD50 in mice (mg/kg): 12.3 i.v. (Antweiler).
Melting point: mp 255-257° (dec)
Toxicity data: Soly in water: ~1 g/2 ml. LD50 in mice (mg/kg): 12.3 i.v. (Antweiler)
Therap-Cat: Antispasmodic; in treatment of urinary incontinence.
Keywords: Antimuscarinic; Antispasmodic.