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CAS No 104713-75-9 , Barnidipine

  • Name: Barnidipine
  • Synonyms: Barnidipine;(+)-(3'S,4S)-1-Benzyl-3-pyrrolidinyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate;
  • CAS Registry Number:
  • Flash Point: 614.5 °C at 760 mmHg
  • Boiling Point: 614.5 °C at 760 mmHg
  • Density: 1.31 g/cm3
  • Refractive index: 1.628
  • Flash Point: 614.5 °C at 760 mmHg
  • Molecular Weight: 491.54
  • InChI: InChI=1/C27H29N3O6/c1-17-23(26(31)35-3)25(20-10-7-11-21(14-20)30(33)34)24(18(2)28-17)27(32)36-22-12-13-29(16-22)15-19-8-5-4-6-9-19/h4-11,14,22,25,28H,12-13,15-16H2,1-3H3/t22-,25?/m0/s1
  • Molecular Formula: C27H29N3O6
  • Molecular Structure:CAS No:104713-75-9 Barnidipine
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104713-75-9 Barnidipine hydrochloride

  • Barnidipine hydrochloride
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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104713-75-9 BARNIDIPINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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104713-75-9 Barnidipine

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104713-75-9 Barnidipine

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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104713-75-9 BARNIDIPINE

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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104713-75-9 Barnidipine

  • Barnidipine
  • United States RIA International [Manufacturer]
  • Tel: 19735811282
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  • Address: 11 Melanie Lane #17 East Hanover 07936 NJ UNITED STATES NJ,nullUnited States
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104713-75-9 Barnidipine

  • Barnidipine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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104713-75-9 Barnidipine

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104713-75-9 Barnidipine Hydrochloride

  • Barnidipine Hydrochloride, 99%UP
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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104713-75-9 Barnidipine

  • India Manus Aktteva null
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, null,nullIndia
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References of Barnidipine
Title: Barnidipine
CAS Registry Number: 104713-75-9
CAS Name: (4S)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl (3S)-1-(phenylmethyl)-3-pyrrolidinyl ester
Synonyms: (+)-(3¢S,4S)-1-benzyl-3-pyrrolidinyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate; (3S)-1-benzyl-3-pyrrolidinyl methyl (4S)-2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; mepirodipine
Molecular Formula: C27H29N3O6
Molecular Weight: 491.54
Percent Composition: C 65.97%, H 5.95%, N 8.55%, O 19.53%
Literature References: Dihydropyridine calcium channel blocker. Prepn (stereochemistry unspecified): T. Kojima, T. Takenaka, DE 2904552; eidem, US 4220649 (1979, 1980 both to Yamanouchi). Prepn and bioactivity of enantiomers: K. Tamazawa et al., J. Med. Chem. 29, 2504 (1986). GC-MS determn in plasma: T. Teramura et al., J. Chromatogr. 528, 191 (1990). Review of pharmacology and therapeutic efficacy: H. Satoh, Cardiovasc. Drug Rev. 9, 340-356 (1991).
Properties: mp 137-139°. [a]D20 +64.8° (c = 1 in methanol).
Melting point: mp 137-139°
Optical Rotation: [a]D20 +64.8° (c = 1 in methanol)
 
Derivative Type: Hydrochloride
CAS Registry Number: 104757-53-1
Manufacturers' Codes: YM-09730-5
Trademarks: Hypoca (Yamanouchi)
Molecular Formula: C27H29N3O6.HCl
Molecular Weight: 528.00
Percent Composition: C 61.42%, H 5.73%, N 7.96%, O 18.18%, Cl 6.71%
Properties: mp 226-228°. [a]D20 +116.4° (c = 1 in methanol). Insol in water. LD50 orally in male, female rats: 105, 113 mg/kg (Satoh).
Melting point: mp 226-228°
Optical Rotation: [a]D20 +116.4° (c = 1 in methanol)
Toxicity data: LD50 orally in male, female rats: 105, 113 mg/kg (Satoh)
 
Therap-Cat: Antihypertensive; antianginal.
Keywords: Antianginal; Antihypertensive; Dihydropyridine Derivatives; Calcium Channel Blocker; Dihydropyridine Derivatives.