Home > Name List By 2 > 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine

CAS No 10540-29-1 , 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine

  • Name: 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
  • Synonyms: Oncomox; Tamoxen; Istubol;Crisafeno; Diemon; Tamizam; Retaxim;2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine; Valodex; Citofen;
  • CAS Registry Number:
  • Melting Point: 97-98 ºC
  • Boiling Point:
  • Density: 1.042 g/cm3
  • Refractive index: 1.582
  • Water Solubility: Insoluble
  • Safety Statements: R45;R60;R61;R64
  • Hazard Symbols: T: Toxic;
  • EINECS: 234-118-0
  • Molecular Weight: 371.51456
  • InchiKey: NKANXQFJJICGDU-QPLCGJKRSA-N
  • InChI: InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-
    17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
  • Risk Statements: S53;S45
  • Molecular Formula: C26H29NO
  • Molecular Structure:CAS No:10540-29-1 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
Search by region :

Select to

10540-29-1 Tamoxifen Citrate

  • 1.product details: Tamoxifen Citrate (Nolvadex) CAS NO.:10540-29-1 Purity: 99.5% Molecular Formula: C26H29NO Molecular Weight: 371.51 Standard:USP27 Assay:99.0~101.0% White crystalline powder . Usage:Breast cancer and oophoroma. Packing: 25kgs drum/ ...
  • China Landmark Nutraceuticals Co.,Limited [Manufacturer]
  • Tel: 86-755-61582048
  • Fax: 86-755-61582048
  • Address: A-1068 Longmen Apt., Mingle Industrial Park, Meiban Ave, Baoan District Shenzhen,GuangdongChina
Contact Supplier

10540-29-1 10540-29-1

  • 10540-29-1
  • China 3w Pharm INC [Manufacturer]
  • Tel: 86-021-51613950
  • Fax: 86-021-51613951
  • Address: D218-219/C333-334,C316-317(LABs) USST National Science Park.128,Xiangyin Road ,Yangpu District, Shanghai,ShanghaiChina
Contact Supplier

10540-29-1 TAMOXIFEN

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
Contact Supplier

10540-29-1 N-DESMETHYL TAMOXIFEN-D4 HCL

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
Contact Supplier

10540-29-1 TAMOXIFEN

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

10540-29-1 TAMOXIFEN

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 null,nullCanada
Contact Supplier

10540-29-1 N-DESMETHYL TAMOXIFEN HCL

  • Canada TLC PharmaChem., Inc. [Manufacturer]
  • Tel: 905-760-1098
  • Fax: 905-760-2098
  • Address: TLC PharmaChem., Inc.
    5-150 Connie Crescent
    Concord, Ontario
    L4K 1L9, Canada null,nullCanada
Contact Supplier

10540-29-1 Tamoxifen

  • Tamoxifen
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,nullChina
Contact Supplier

10540-29-1 Tamoxifen

  • Tamoxifen
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
Contact Supplier

10540-29-1 tamoxifen drug standard solution

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
  • Fax: +86-21-58408291
  • Address: 1213 JunMin Road,Pudong,China null,nullChina
Contact Supplier

Select to

References of 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
Title: Tamoxifen
CAS Registry Number: 10540-29-1
CAS Name: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine
Synonyms: 1-p-b-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
Molecular Formula: C26H29NO
Molecular Weight: 371.51
Percent Composition: C 84.06%, H 7.87%, N 3.77%, O 4.31%
Literature References: Nonsteroidal estrogen antagonist. Prepn: BE 637389 (1964 to ICI). Identification and separation of isomers: G. R. Bedford, D. N. Richardson, Nature 212, 733 (1966); BE 678807; M. J. K. Harper et al., US 4536516 (1966, 1985 both to ICI). Stereospecific synthesis: R. B. Miller, M. I. Al-Hassan, J. Org. Chem. 50, 2121 (1985). Review of chemistry and pharmacology: B. J. A. Furr, V. C. Jordan, Pharmacol. Ther. 25, 127-205 (1984). Reviews of clinical experience in treatment and prevention of breast cancer: I. A. Jaiyesimi et al., J. Clin. Oncol. 13, 513-529 (1995); C. K. Osborne, N. Engl. J. Med. 339, 1609-1618 (1998).
Properties: Crystals from petr ether, mp 96-98°.
Melting point: mp 96-98°
 
Derivative Type: Citrate
CAS Registry Number: 54965-24-1
Manufacturers' Codes: ICI-46474
Trademarks: Kessar (Pharmacia); Nolvadex (AstraZeneca); Tamofène (Aventis); Zemide (Alpharma); Zitazonium (Servier)
Molecular Formula: C26H29NO.C6H8O7
Molecular Weight: 563.64
Percent Composition: C 68.19%, H 6.62%, N 2.49%, O 22.71%
Properties: Fine, white, odorless crystalline powder, mp 140-142°. Slightly sol in water; sol in ethanol, methanol, acetone. Hygroscopic at high relative humidities. Sensitive to uv light. LD50 in mice, rats (mg/kg): 200, 600 i.p.; 62.5, 62.5 i.v.; 3000-6000, 1200-2500 orally (Furr, Jordan).
Melting point: mp 140-142°
Toxicity data: LD50 in mice, rats (mg/kg): 200, 600 i.p.; 62.5, 62.5 i.v.; 3000-6000, 1200-2500 orally (Furr, Jordan)
 
Derivative Type: (E)-Form
CAS Registry Number: 13002-65-8
Properties: mp 72-74° from methanol.
Melting point: mp 72-74° from methanol
 
Derivative Type: (E)-Form citrate
Manufacturers' Codes: ICI-47699
Properties: mp 126-128°.
Melting point: mp 126-128°
 
CAUTION: Tamoxifen is listed as a known human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-239.
Therap-Cat: Antineoplastic (hormonal).
Keywords: Antineoplastic (Hormonal); Antiestrogens; Selective Estrogen Receptor Modulator (SERM).