Home > Name List By 2 > 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N, N-dimethylethanamine

CAS No 89778-26-7 , 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,
N-dimethylethanamine

  • Name: 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,
    N-dimethylethanamine
  • Synonyms: Toremifene Base; Farestone;2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,
    N-dimethylethanamine; Toremifeno; Toremifenum; Toremifeno [Spanish]; Toremifenum [Latin]; 89778-26-7; Z-Toremifene;Acapodene;
  • CAS Registry Number:
  • Density: 1.104 g/cm3
  • Molecular Weight: 405.95962
  • InchiKey: XFCLJVABOIYOMF-QPLCGJKRSA-N
  • InChI: InChI=1S/C26H28ClNO/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-
    8-12-22)25(17-18-27)21-9-5-3-6-10-21/h3-16H,17-20H2,1-2H3/b26-25-
  • Molecular Formula: C26H28ClNO
  • Molecular Structure:CAS No:89778-26-7 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,<br />N-dimethylethanamine
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89778-26-7 Toremifene citrate

  • Changland focus on Pharmaceutical Chemicals since 2001, produce APIs, health supplements raw materials, steroids, cosmetic raw materials and their finished tablets&injection. Have been already offered to Australia, America and Europe for many years. ...
  • China Changland Technology Co.,Ltd [Manufacturer]
  • Tel: 86-027-87290616
  • Fax: 86-027-68786490
  • Address: zhongnan road Wuhan,HubeiChina

89778-26-7 Toremifene

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89778-26-7 Ethanamine,2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

  • China HuaiBei SanHe Developing Co., Ltd. [Manufacturers]
  • Tel: 86-561-3191113
  • Fax: +86-561-3192253
  • Address: Room 201,Building ZY-1,GuCheng Road,Huaibei,Anhui,China null,anhuiChina
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89778-26-7 Toremifene citrate

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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89778-26-7 Toremifene citrate

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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89778-26-7 TOREMIFENE CITRATE

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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89778-26-7 TOREMIFENE

  • China IFFECT CHEMPHAR CO., LTD. null
  • Tel: 0086 755-83761619 83760606
  • Fax: +86-25- 84270111
  • Address: 15A,Changfa Center, Building B ,No. 300,East Zhongshan Road,Baixia District,Nanjing,210002, P.R.China. Nanjing,JiangshuChina
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89778-26-7 Toremifene

  • China EASYBUYER LTD., [Manufacturers]
  • Tel: +86-21-35015877 +86-13701868511
  • Fax: +86-21-35010877
  • Address: Room 407, Building 10, Hi-Shanghai Center, No.990 Dalian Rd,Shanghai 200092 China null,ShanghaiChina
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89778-26-7 Ethanamine,2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

  • China Ningbo Huajia Chemical Co., Ltd. null
  • Fax: 86-574-87065629
  • Address: 10th Floor, Lishi Building, No.787 Baizhang East Road, Ningbo, Zhejiang, China null,nullChina
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89778-26-7 Ethanamine,2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

  • China Renyoung pharmaceutical co.,Ltd [Manufacturers]
  • Tel: 86-21-35015877
  • Fax: 86-21-35010877
  • Address: Room 407,Bldg 10 Hi-Shanghai Center,No.990 Dalian RD, Shanghai,shanghaiChina
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References of 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,
N-dimethylethanamine
Title: Toremifene
CAS Registry Number: 89778-26-7
CAS Name: 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine
Synonyms: (Z)-4-chloro-1,2-diphenyl-1-[4-[2-(N,N-dimethylamino)ethoxy]phenyl]-1-butene
Molecular Formula: C26H28ClNO
Molecular Weight: 405.96
Percent Composition: C 76.92%, H 6.95%, Cl 8.73%, N 3.45%, O 3.94%
Literature References: Nonsteroidal antiestrogen structurally similar to tamoxifen, q.v. Prepn: R. J. Toivola et al., EP 95875; eidem, US 4696949 (1983, 1987 both to Farmos). Pharmacology: S. Kallio et al., Cancer Chemother. Pharmacol. 17, 103 (1986). Antitumor effects in vitro and in vivo: L. Kangas et al., ibid. 109. HPLC determn in plasma: W. M. Holleran et al., Anal. Lett. 20, 871 (1987). Clinical evaluation in high-grade prostatic intraepithelial neoplasia: M. S. Steiner, C. R. Pound, Clin. Prostate Cancer 2, 24 (2003). Review of pharmacology and clinical efficacy in advanced breast cancer: L. R. Wiseman, K. L. Goa, Drugs 54, 141-160 (1997); in postmenopausal breast cancer: J. U. M?enp??, S.-L. Ala-Fossi, Drugs Aging 11, 261-270 (1997).
Properties: mp 108-110°.
Melting point: mp 108-110°
 
Derivative Type: Citrate
CAS Registry Number: 89778-27-8
Manufacturers' Codes: FC-1157a
Trademarks: Acapodene (GTx); Fareston (Farmos)
Molecular Formula: C26H28ClNO.C6H8O7
Molecular Weight: 598.08
Percent Composition: C 64.26%, H 6.07%, Cl 5.93%, N 2.34%, O 21.40%
Properties: mp 160-162°.
Melting point: mp 160-162°
 
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic (Hormonal); Antiestrogens; Selective Estrogen Receptor Modulator (SERM).