Home > Name List By other > [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl] oxymethylphosphonic acid

CAS No 113852-37-2 , [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]
oxymethylphosphonic acid

  • Name: [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]
    oxymethylphosphonic acid
  • Synonyms: Cidofovirum; HPMPC;[(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]
    oxymethylphosphonic acid; Cidofovir; Vistide; (S)-HPMPC; Cidofovir anhydrous; Forvade;Vistide; GS-504; 113852-37-2;
  • CAS Registry Number:
  • Melting Point: 260
  • Density: 1.76 g/cm3
  • Refractive index: 1.656
  • Safety Statements: A severe skin irritant. When heated to decomposition it emits toxic vapors of NOx and POx.
  • Hazard Symbols: A severe skin irritant.
  • Molecular Weight: 279.187022
  • InchiKey: VWFCHDSQECPREK-LURJTMIESA-N
  • InChI: InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,
    15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1
  • Molecular Formula: C8H14N3O6P
  • Molecular Structure:CAS No:113852-37-2 [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]<br />oxymethylphosphonic acid
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113852-37-2 Cidofovir

  • product Name Cidofovir Synonyms Cidofovir (anhydrous); (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; (S)-HPMPC; UNII-768M1V522C; Phosphonic acid, ((2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy)methyl)-, (S)-; ({[(2S)-1-(4-amino-2...
  • China Hangzhou Merry Chemical Co.,Ltd [Trading Company]
  • Tel: 86-182-57110923
  • Fax: --
  • Address: 233 Wensan Road , Xihu Area , Hangzhou hangzhu,ZhejiangChina
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113852-37-2 Cidofovir

  • Cidofovir
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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113852-37-2 CIDOFOVIR

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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113852-37-2 Cidofovir

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
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113852-37-2 Cidofovir

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113852-37-2 Cidofovir

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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113852-37-2 Cidofovir

  • 113852-37-2 瑗垮?绂?? Cidofovir B121282
  • China bepharm ltd. []
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China ,China
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113852-37-2 (R)-4-(4-AMINO-2-OXOPYRIMIDIN-1(2H)-YL)-3-(HYDROXYMETHYL)BUTYLPHOSPHONIC ACID

  • China Shanghai SynCores Technologies Inc. [Manufacturer]
  • Tel: 86-21-51320499
  • Fax: 86-21-51320497
  • Address: Cailun road 538#,
    ZhangJiang Hi-Tech park,
    Pudong, Shanghai, P.R.China ,China
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113852-37-2 Cidofovir

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113852-37-2 Cidofovir

  • Cidofovir, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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References of [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]
oxymethylphosphonic acid
Title: Cidofovir
CAS Registry Number: 113852-37-2
CAS Name: [[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid
Synonyms: (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine; (S)-HPMPC
Manufacturers' Codes: GS-504
Trademarks: Vistide (Gilead)
Molecular Formula: C8H14N3O6P
Molecular Weight: 279.19
Percent Composition: C 34.42%, H 5.05%, N 15.05%, O 34.38%, P 11.09%
Literature References: DNA synthesis inhibitor. Prepn: A. Holy et al., EP 253412; eidem, US 5142051 (1988, 1992 both to Ceskoslov. Akad. Ved; Rega Inst.); and activity vs cytomegalovirus: R. Snoeck et al., Antimicrob. Agents Chemother. 32, 1839 (1988). Syntheses: J. J. Bronson et al., Nucleosides Nucleotides 9, 745 (1990); P. R. Brodfuehrer et al., Tetrahedron Lett. 35, 3243 (1994). Activity vs herpes simplex virus: G. Andrei et al., Eur. J. Clin. Microbiol. Infect. Dis. 11, 143 (1992). Review of pharmacology and clinical studies: M. J. M. Hitchcock et al., Antiviral Chem. Chemother. 7, 115-127 (1996). Review of clinical potential in poxvirus infections: E. De Clercq, Trends Pharmacol. Sci. 23, 456-458 (2002).
Properties: Fluffy white powder, mp 260° (dec). [a]D20 -97.3° (c = 0.80 in water). Monohydrate, uv max (pH 2): 279 nm (e 13000).
Melting point: mp 260° (dec)
Optical Rotation: [a]D20 -97.3° (c = 0.80 in water)
Absorption maximum: uv max (pH 2): 279 nm (e 13000)
Therap-Cat: Antiviral.
Keywords: Antiviral; Purines/Pyrimidinones.