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CAS No 122898-67-3 , N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide Search by region : China

  • Name: N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide
  • Synonyms: 122898-67-3;N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide; NCGC00167529-01; n-{4-[2-(dimethylamino)ethoxy]benzyl}-3,4-dimethoxybenzamide;
  • CAS Registry Number:
  • Flash Point: 262.3°C
  • Boiling Point: 510.1°Cat760mmHg
  • Density: 1.122g/cm3
  • Refractive index: 1.552
  • Flash Point: 262.3°C
  • Molecular Weight: 358.43144
  • InchiKey: QQQIECGTIMUVDS-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H26N2O4/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-
    10-18(24-3)19(13-16)25-4/h5-10,13H,11-12,14H2,1-4H3,(H,21,23)
  • Molecular Formula: C20H26N2O4
  • Molecular Structure:CAS No:122898-67-3 N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide

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122898-67-3 Itopride

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
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122898-67-3 ITOPRIDE

  • China Taizhou Creating Chemical Co.,Ltd [Manufacturer]
  • Tel: +86-576-88827176/ +86-576-88820069
  • Fax: +86-576-88822496
  • Address: B Suite 12F,
    Jiangbin Building,Jiaojiang,Taizhou,
    Zhejiang China null,nullChina
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122898-67-3 Itopride

  • China Xilin Chemical Group Co., Ltd null
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, null,nullChina
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122898-67-3 Itopride

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122898-67-3 ITOPRIDE

  • China Cangzhou Goldlion Chemicals Co., Ltd [Manufacturer]
  • Tel: +86-317-3781622/ +86-317-2180702
  • Fax: +86-317-3200988, 2180702
  • Address: 5-1-402, NO.32 Yuhe Road
    Cangzhou
    China null,nullChina
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122898-67-3 Itopride

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122898-67-3 Itopride

  • China Hwasun Biotechnology Co., Ltd. null
  • Fax: 86-21-64765024
  • Address: Rm.505, Bldg. 2,No. 245 Jiachuan RD. Xuhui Dist.,200237, Shanghai, China null,nullChina
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122898-67-3 Itopride

  • China Shanghai Richem International Co., Ltd. null
  • Tel: +86-(21)-31263688
  • Fax: +86-(21)-51862199
  • Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road, Pudong, Shanghai 200135, shanghai,shanghaiChina
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122898-67-3 ITOPRIDE

  • China Shanghai Urchem Limited null
  • Tel: 0086-21-58600951
  • Fax: +086-021-58604179
  • Address: 830, 1500 Century Avenue ,Shanghai 200122 China null,nullChina
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122898-67-3 Itopride

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References of N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide
Title: Itopride
CAS Registry Number: 122898-67-3
CAS Name: N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamide
Synonyms: N-[p-[2-(dimethylamino)ethoxy]benzyl]veratramide
Molecular Formula: C20H26N2O4
Molecular Weight: 358.43
Percent Composition: C 67.02%, H 7.31%, N 7.82%, O 17.85%
Literature References: Dopamine D2-receptor antagonist with anticholinesterase activity. Prepn: Y. Itoh et al., EP 306827; eidem, US 4983633 (1989, 1991 both to Hokuriku Pharm.); J. Sakaguchi et al., Chem. Pharm. Bull. 40, 202 (1992). Pharmacology: Y. Iwanaga et al., Jpn. J. Pharmacol. 56, 261 (1991). Toxicity studies: M. H. Barker et al., Yakuri to Chiryo 21, 1685, 1669 (1993). Metabolism study: T. Mushiroda et al., Drug Metab. Dispos. 28, 1231 (2000). HPLC determn in serum and clinical pharmacokinetics: S. S. Singh et al., J. Chromatogr. B 818, 213 (2005). Clinical study in postoperative ileus: R. Gürlich et al., Chir. Gastroenterol. Interdiszip. 20, 61 (2004); in dyspepsia: D. N. Amarapurkar, P. Rane, J. Indian Med. Assoc. 102, 735 (2004).
Properties: Crystals from ethanol + isopropyl ether, mp 111-112°.
Melting point: mp 111-112°
 
Derivative Type: Hydrochloride
CAS Registry Number: 122892-31-3
Manufacturers' Codes: HSR-803; HC-803
Trademarks: Itax (Axcan); Ganaton (Abbott)
Molecular Formula: C20H26N2O4.HCl
Molecular Weight: 394.89
Percent Composition: C 60.83%, H 6.89%, N 7.09%, O 16.21%, Cl 8.98%
Properties: Crystals from ethanol, mp 194-195°. Also reported as prisms from ethanol, mp 190.5-191.5° (Sakaguchi). Readily sol in water.
Melting point: mp 194-195°; mp 190.5-191.5° (Sakaguchi)
 
Therap-Cat: Gastroprokinetic.
Keywords: Gastroprokinetic.