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CAS No 82413-20-5 , 3-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol

  • Name: 3-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
  • Synonyms: K 21060E; FK-435; Droloxifenum [Latin];E-Droloxifene; K 060;3-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol; K 060E; 82413-20-5; Droloxifeno [Spanish]; 3-HYDROXYTAMOXIFEN;
  • CAS Registry Number:
  • Flash Point: 526.6 °C at 760 mmHg
  • Boiling Point: 526.6 °C at 760 mmHg
  • Density: 1.092 g/cm3
  • Refractive index: 1.596
  • Flash Point: 526.6 °C at 760 mmHg
  • EINECS: 428-010-4
  • Molecular Weight: 387.51396
  • InchiKey: ZQZFYGIXNQKOAV-OCEACIFDSA-N
  • InChI: InChI=1S/C26H29NO2/c1-4-25(20-9-6-5-7-10-20)26(22-11-8-12-23(28)19-22)
    21-13-15-24(16-14-21)29-18-17-27(2)3/h5-16,19,28H,4,17-18H2,
    1-3H3/b26-25+
  • Molecular Formula: C26H29NO2
  • Molecular Structure:CAS No:82413-20-5 3-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
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82413-20-5 Phenol,3-[(1E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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82413-20-5 Codeine base

  • Codeine base
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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82413-20-5 Droloxifene

  • Droloxifene, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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82413-20-5 Droloxifene

  • Droloxifene, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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82413-20-5 Droloxifene citrate

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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82413-20-5 Droloxifene citrate

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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82413-20-5 Droloxifene, 99%

  • Droloxifene, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,China
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82413-20-5 Droloxifene citrate

  • Droloxifene citrate
  • United States Carbomer, Inc. [Manufacturer]
  • Tel: 858-552-0992/ (800) 239-7129
  • Fax: 858-552-0999
  • Address: PO Box 261026-1026
    San Diego, CA 92196 ,United States
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82413-20-5 Droloxifene citrate

  • United States Medical Isotopes, Inc. [Manufacturers]
  • Tel: +1-(603)-635-2255
  • Fax: +1-(603)-635-2448
  • Address: 100 Bridge Street, Pelham, New Hampshire 03076, Pelham,New HampshireUnited States
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82413-20-5 Phenol,3-[(1E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

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References of 3-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
Title: Droloxifene
CAS Registry Number: 82413-20-5
CAS Name: 3-[(1E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol
Synonyms: (E)-a-[p-[2-(dimethylamino)ethoxy]phenyl]-a¢-ethyl-3-stilbenol; (E)-1-[4¢-(2-dimethylaminoethoxy)phenyl]-1-(3-hydroxyphenyl)-2-phenylbut-1-ene; 3-hydroxytamoxifen
Molecular Formula: C26H29NO2
Molecular Weight: 387.51
Percent Composition: C 80.59%, H 7.54%, N 3.61%, O 8.26%
Literature References: Estrogen-receptor antagonist. Prepn: H. Schickaneder et al., EP 54168; eidem, US 5047431 (1982, 1991 both to Klinge); P. C. Ruenitz et al., J. Med. Chem. 25, 1056 (1982). Symposium on pharmacology and clinical studies: Am. J. Clin. Oncol. 14, Suppl. 2, S1-S63 (1991). Clinical trial in breast cancer: P. F. Bruning, Eur. J. Cancer 28A, 1404 (1992).
Properties: Colorless crystals from ether, mp 162-163° (Schickaneder); also reported as white crystals from benzene-hexane, mp 160-162° (Ruenitz).
Melting point: mp 162-163° (Schickaneder); mp 160-162° (Ruenitz)
 
Derivative Type: Citrate
CAS Registry Number: 97752-20-0
Manufacturers' Codes: K-21060E; FK-435
Molecular Formula: C26H29NO2.C6H8O7
Molecular Weight: 579.64
Percent Composition: C 66.31%, H 6.43%, N 2.42%, O 24.84%
Properties: Slightly sol in water, methanol, ethanol. Insol in chloroform.
 
Therap-Cat: Antineoplastic (hormonal).
Keywords: Antineoplastic (Hormonal); Antiestrogens; Selective Estrogen Receptor Modulator (SERM).