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CAS No 123040-69-7 , 2H-1,4-Benzoxazine-8-carboxamide,N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-

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123040-69-7 Good Quality Pharmaceutical Intermediates Azasetron Hydrochloride /Skype:ling@chembj.com

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123040-69-7 Good Quality Pharmaceutical Intermediates Azasetron Hydrochloride

  • Good Quality Pharmaceutical Intermediates Azasetron Hydrochloride Product Name: Azasetron hydrochloride CAS No.:123040-69-7 / 123040-16-4 / 141922-90-9 Molecular Formula: C17H21Cl2N3O3 Molecular Weight: 386.2729 Melting point: 35-37℃ Appearance: whi...
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123040-69-7 Azasetron hydrochloride

  • Azasetron hydrochloride Good Quality Pharmaceutical Intermediates Azasetron Hydrochloride Product Name: Azasetron hydrochloride CAS No.:123040-69-7 / 123040-16-4 / 141922-90-9 Molecular Formula: C17H21Cl2N3O3 Molecular Weight: 386.2729 Melting point:...
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123040-69-7 azasetron

  • azasetron Azasetron, Hydrochloride N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride AZASETRON HCL Azaseton HCl Azasetron hydrochloride Pentorex N-1-Azabicyclo[2.2.2]Oct-3-Yl-6-Chloro-3...
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123040-69-7 Azasetron hydrochloride

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123040-69-7 Azasetron hydrochloride

  • duosue at chembj dot com skype: gina.yctech whats-----app ID: +8618872220799 wechat ID: hq030818 hi,dear friend welcome to our online shop if you want buy high purity pharm raws with competive price and safe delivery Congratulations because you get t...
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123040-69-7 Good Quality Pharmaceutical Intermediates Azasetron Hydrochloride

  • Good Quality Pharmaceutical Intermediates Azasetron Hydrochloride Product Name: Azasetron hydrochloride CAS No.:123040-69-7 / 123040-16-4 / 141922-90-9 Molecular Formula: C17H21Cl2N3O3 Molecular Weight: 386.2729 Melting point: 35-37℃ Appearance: whi...
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123040-69-7 Azasetron HCL

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123040-69-7 Azasetron

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123040-69-7 2H-1,4-Benzoxazine-8-carboxamide,N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-

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References of 2H-1,4-Benzoxazine-8-carboxamide,N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-
Title: Azasetron
CAS Registry Number: 123040-69-7
CAS Name: N-1-Azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide
Synonyms: (±)-6-chloro-3,4-dihydro-4-methyl-3-oxo-N-(3-quinuclidinyl)-2H-1,4-benzoxazine-8-carboxamide; nazasetron
Molecular Formula: C17H20ClN3O3
Molecular Weight: 349.81
Percent Composition: C 58.37%, H 5.76%, Cl 10.13%, N 12.01%, O 13.72%
Literature References: Serotonin 5-HT3 receptor antagonist. Prepn: T. Tahara et al., EP 313393; eidem, US 4892872 (1989, 1990 both to Yoshitomi); T. Kawakita et al., Chem. Pharm. Bull. 40, 624 (1992). Receptor binding study: N. Sato et al., Jpn. J. Pharmacol. 59, 443 (1992). Pharmacology: K. Haga et al., ibid. 63, 377 (1993). Toxicity study: S. Takagi et al., Oyo Yakuri 42, 255 (1991), C.A. 117, 40208q (1991).
 
Derivative Type: Hydrochloride
CAS Registry Number: 123040-16-4
Manufacturers' Codes: Y-25130
Trademarks: Serotone (Yoshitomi; Japan Tobacco)
Molecular Formula: C17H20ClN3O3.HCl
Molecular Weight: 386.27
Percent Composition: C 52.86%, H 5.48%, Cl 18.36%, N 10.88%, O 12.43%
Properties: Crystals from ethanolic HCl, mp 281° (dec). Also reported as crystals from ethanol, mp 305° (dec) (Kawakita). LD50 in male, female rats (mg/kg): 135, 132 i.v. (Takagi).
Melting point: mp 281° (dec); mp 305° (dec) (Kawakita)
Toxicity data: LD50 in male, female rats (mg/kg): 135, 132 i.v. (Takagi)
 
Therap-Cat: Antiemetic.
Keywords: Antiemetic; Serotonin Receptor Antagonist.