Home > Name List By other > (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16, 17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15, 16-octah... France

CAS No 124-94-7 , (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,
17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,
16-octahydrocyclopenta[a]phenanthren-3-one Search by region : France

  • Name: (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,
    17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthren-3-one
  • Synonyms: Aristocort; Volon; Adcortyl; Triamcinolon;(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,
    17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthren-3-one; Delphicort; Ledercort;Fluoxyprednisolone; Rodinolone; Kenacort;
  • CAS Registry Number:
  • Transport: OTH
  • Melting Point: 260-263 ºC (DEC.)
  • Flash Point: 309.1°C
  • Boiling Point: 587.5°Cat760mmHg
  • Density: 1.42g/cm3
  • Refractive index: 1.617
  • Alpha: 69 º (C=2, DMF)
  • Water Solubility: Practically insoluble (soluble in alcohol, chloroform)
  • Safety Statements: R40
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 309.1°C
  • EINECS: 204-718-7
  • Molecular Weight: 394.433883
  • InchiKey: GFNANZIMVAIWHM-OBYCQNJPSA-N
  • InChI: InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,
    17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,
    8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
  • Risk Statements: S22;S36
  • Molecular Formula: C21H27FO6
  • Molecular Structure:CAS No:124-94-7 (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,<br />17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,<br />16-octahydrocyclopenta[a]phenanthren-3-one

Related products

Select to

124-94-7 Oxytocin

  • Oxytocin
  • France NeoMPS [Manufacturer]
  • Tel: + 33 3 88 79 87 04
  • Fax: + 33 3 88 79 18 56
  • Address: NeoMPS SA7 rue de Boulogne67100 StrasbourgFRANCE Strasbourg,nullFrance
Contact Supplier

Select to

1/1
References of (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,
17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,
16-octahydrocyclopenta[a]phenanthren-3-one
Title: Triamcinolone
CAS Registry Number: 124-94-7
CAS Name: (11b, 16a)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
Synonyms: D1-9a-fluoro-16a-hydroxyhydrocortisone; 9a-fluoro-16a-hydroxyprednisolone; D1-16a-hydroxy-9a-fluorohydrocortisone; 16a-hydroxy-9a-fluoroprednisolone
Manufacturers' Codes: CL-19823
Trademarks: Aristocort (Lederle); Kenacort (BMS); Ledercort (tabl.) (Lederle); Omcilon (BMS); Tricortale (Bergamon); Volon (BMS)
Molecular Formula: C21H27FO6
Molecular Weight: 394.43
Percent Composition: C 63.95%, H 6.90%, F 4.82%, O 24.34%
Literature References: Prepn: Bernstein et al., J. Am. Chem. Soc. 78, 5693 (1956); 81, 1689 (1959); Thoma et al., ibid. 79, 4818 (1957); Bernstein et al., Allen et al., US 2789118; US 3021347 (1957, 1962, both to Am. Cyanamid). Comprehensive description: K. Florey, Anal. Profiles Drug Subs. 1, 367-396, 423-442 (1972); D. H. Sieh, ibid. 11, 593-614, 651-661 (1982).
Properties: Crystals, mp 269-271°. mp also reported as 260-262.5°. [a]D25 +75° (acetone). uv max: 238 nm (e 15800).
Melting point: mp 269-271°; mp also reported as 260-262.5°
Optical Rotation: [a]D25 +75° (acetone)
Absorption maximum: uv max: 238 nm (e 15800)
 
Derivative Type: 16,21-Diacetate
CAS Registry Number: 67-78-7
CAS Name: (11b,16a)-16,21-Bis(acetyloxy)-9-fluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione
Synonyms: 16a,21-diacetoxy-9a-fluoro-11b,17a-dihydroxy-1,4-pregnadiene-3,20-dione
Trademarks: Cenocort (Central Pharm.); CINO-40 (Tutag); Tracilon (Savage)
Molecular Formula: C25H31FO8
Molecular Weight: 478.51
Percent Composition: C 62.75%, H 6.53%, F 3.97%, O 26.75%
Properties: Solvated crystals, mp 186-188° (with effervescence, mp 235° after drying). [a]D25 +22° (chloroform). uv max: 239 nm (e 15200).
Melting point: Solvated crystals, mp 186-188° (with effervescence, mp 235° after drying)
Optical Rotation: [a]D25 +22° (chloroform)
Absorption maximum: uv max: 239 nm (e 15200)
 
Therap-Cat: Glucocorticoid.
Therap-Cat-Vet: Glucocorticoid.
Keywords: Glucocorticoid.