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CAS No 127-79-7 , 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide

  • Name: 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
  • Synonyms: Cremomerazine;4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide; Methylpyrimal; Mebacid; Kelamerazine; Sulfameradine; Sulfamethyldiazine; Sulfamerazin;Sulphamerazine;
  • CAS Registry Number:
  • Density: 1.439 g/cm3
  • Refractive index: 1.66
  • Water Solubility: slightly bitter; slightly soluble in ethanol and water
  • Safety Statements: Moderately toxic by intravenous and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 204-866-2
  • Molecular Weight: 264.30358
  • InchiKey: QPPBRPIAZZHUNT-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,
    17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
  • Risk Statements: S22:Donotinhaledust.;S24/25:Avoidcontactwithskinandeyes.;
  • Molecular Formula: C11H12N4O2S
  • Molecular Structure:CAS No:127-79-7 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
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127-79-7 Sulfamerazine

  • Product Name: Sulfamerazine Synonyms: DEBENAL;LABOTEST-BB LT00455132;METSULFA;METHYLPYRIMAL;4-METHYL-2-SULFANILAMIDO-PYRIMIDINE;4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE;4-AMINO-N-(4-METHYL-PYRIMIDIN-2-YL)-BENZENESULFONAMIDE;2-SULFANILAMI...
  • Min. Order: 500
  • FOB Price: USD0.5 - 1 /
  • China Wuhan Hezhong Bio-Chemical Manufature Co.,Ltd [Manufacturer]
  • Tel: 86-27-50756046
  • Address: Zhongshan Road No 496 Wuhan,HubeiChina
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127-79-7 Sulfamerazine 127-79-7

  • Sulfamerazine 127-79-7 Synonyms: DEBENAL;LABOTEST-BB LT00455132;METSULFA;METHYLPYRIMAL;4-METHYL-2-SULFANILAMIDO-PYRIMIDINE;4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE;4-AMINO-N-(4-METHYL-PYRIMIDIN-2-YL)-BENZENESULFONAMIDE;2-SULFANILAMIDO-4-...
  • China Hubei Yuancheng Saichuang Technology Co.Ltd [Manufacturer]
  • Tel: 86-027-50756140
  • Address: Zhongshan Road Wuhan,HubeiChina
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127-79-7 Sulfamerazine

  • Product Name: Sulfamerazine Synonyms: DEBENAL;LABOTEST-BB LT00455132;METSULFA;METHYLPYRIMAL;4-METHYL-2-SULFANILAMIDO-PYRIMIDINE;4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE;4-AMINO-N-(4-METHYL-PYRIMIDIN-2-YL)-BENZENESULFONAMIDE;2-SULFANILAMI...
  • China Hubei Yuancheng Saichuang Technology Co.Ltd [Manufacturer]
  • Tel: 86-027-50756140
  • Address: Zhongshan Wuhan,HubeiChina
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127-79-7 Sulfamerazine

  • Product Name: Sulfamerazine Synonyms: DEBENAL;LABOTEST-BB LT00455132;METSULFA;METHYLPYRIMAL;4-METHYL-2-SULFANILAMIDO-PYRIMIDINE;4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE;4-AMINO-N-(4-METHYL-PYRIMIDIN-2-YL)-BENZENESULFONAMIDE;2-SULFANILAMI...
  • Min. Order: 100
  • FOB Price: USD0.5 - 1 /
  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd. [Manufacturer]
  • Tel: 86-27-50756064
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
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127-79-7 SULFAMERAZINE CRYSTALLINE

  • SULFAMERAZINE CRYSTALLINE
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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127-79-7 Sulfamerazine

  • Sulfamerazine Product Name: Sulfamerazine Synonyms: DEBENAL;LABOTEST-BB LT00455132;METSULFA;METHYLPYRIMAL;4-METHYL-2-SULFANILAMIDO-PYRIMIDINE;4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE;4-AMINO-N-(4-METHYL-PYRIMIDIN-2-YL)-BENZENESULFONAMIDE...
  • Min. Order: 100000
  • FOB Price: USD1 - 2 /
  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd. [Manufacturer]
  • Tel: 86-027-50756052
  • Fax: 86-027-68886696
  • Address: No.496,Zhongshan Road Wuhan,HubeiChina
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  • 127-79-7 Sulfamerazine

    • Sulfamerazine Product Name: Sulfamerazine sulfamerazine free acid Synonyms: DEBENAL;LABOTEST-BB LT00455132;METSULFA;METHYLPYRIMAL;4-METHYL-2-SULFANILAMIDO-PYRIMIDINE;4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE;4-AMINO-N-(4-METHYL-PYRIMIDIN-...
    • FOB Price: USD400 - 600 /
    • China Hubei Yuancheng Gongchuang Technology Co.,Ltd [Manufacturer]
    • Tel: 86-027-50755970
    • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
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    127-79-7 SULFAMERAZINE

    • Germany CHEMOS GmbH [Manufacturer]
    • Tel: 0049 9402/9336 0
    • Fax: 0049 9402/9336 13
    • Address: CHEMOS GmbH
      Werner-von-Siemensstr. 3
      93128 Regenstauf
      Germany null,nullGermany
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    127-79-7 LTS00809 SULFAMERAZINE

    • Hong kong Lotus chemical (HK) Limited [Manufacturer]
    • Tel: +86 23 86092822 (China)/ +852 29738324 (Hong Kong)
    • Fax: +86 23 86092822
    • Address: Lotus Chemical Limited,. (China office)
      Address: 602 Room, 172#, Gaoyan Road, Yubei District, Chongqing, China
      Postcode: 401120 null,nullHong kong
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    127-79-7 Sulfamerazine

    • Sulfamerazine
    • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
    • Tel: +86-28-88007744
    • Fax: +86-28-85193812
    • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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    References of 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
    Title: Sulfamerazine
    CAS Registry Number: 127-79-7
    CAS Name: 4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide
    Synonyms: N1-(4-methyl-2-pyrimidyl)sulfanilamide; N1-(4-methyl-2-pyrimidinyl)sulfanilamide; 2-sulfanilamido-4-methylpyrimidine; sulfamethyldiazine
    Manufacturers' Codes: RP-2632
    Trademarks: Mesulfa (Triosol); Percoccide (A.C.F.)
    Molecular Formula: C11H12N4O2S
    Molecular Weight: 264.30
    Percent Composition: C 49.99%, H 4.58%, N 21.20%, O 12.11%, S 12.13%
    Literature References: Prepd by condensing 2-amino-4-methylpyrimidine with acetylsulfanilyl chloride followed by hydrolysis of the acetyl group: Roblin et al., J. Am. Chem. Soc. 62, 2002 (1940); Sprague et al., ibid. 63, 3028 (1941); Sprague, US 2407966 (1946 to Sharp & Dohme). For prepn of 2-amino-4-methylpyrimidine see Benary, Ber. 63, 2601 (1930); Backer, Grevenstuk, Rec. Trav. Chim. 61, 291 (1942); cf. E. H. Northey, Sulfonamides (Reinhold, New York, 1948). Antimicrobial activity: Gill et al., Indian J. Vet. Sci. 32, 240 (1962); Vaichulis, Vedros, Chemotherapia 11, 315 (1966). Toxicity studies: Simunek et al., Vet. Med. (Prague) 13, 619 (1968). Kinetics of sulfamerazine decompn: Zajac, Diss. Pharm. Pharmacol. 22, 455 (1970). Comprehensive description: R. D. G. Woolfenden, Anal. Profiles Drug Subs. 6, 515-577 (1977).
    Properties: Crystals, mp 234-238°. uv max (water): 243, 257 nm (E1%1cm 875, 822); (0.1M HCl): 243, 307 nm (E1%1cm 625, 200); (ethanol): 271 nm (E1%1cm 835). Slowly darkens on exposure to light. Soly in water at 37°: 35 mg/100 ml at pH 5.5; 170 mg/100 ml at pH 7.5. Readily sol in dil mineral acids and in solns of potassium, ammonium and sodium hydroxides. Sparingly sol in acetone, slightly sol in alcohol, very slightly sol in ether, chloroform.
    Melting point: mp 234-238°
    Absorption maximum: uv max (water): 243, 257 nm (E1%1cm 875, 822); (0.1M HCl): 243, 307 nm (E1%1cm 625, 200); (ethanol): 271 nm (E1%1cm 835)
     
    Derivative Type: Monosodium salt
    CAS Registry Number: 127-58-2
    Synonyms: Soluble sulfamerazine
    Trademarks: Solumédine (Specia)
    Molecular Formula: C11H11N4NaO2S
    Molecular Weight: 286.29
    Percent Composition: C 46.15%, H 3.87%, N 19.57%, Na 8.03%, O 11.18%, S 11.20%
    Properties: Crystals. Bitter, caustic taste. Hygroscopic. On prolonged exposure to humid air, it absorbs CO2 with the liberation of sulfamerazine and becomes incompletely sol in water. Its solns are alkaline to phenolphthalein (pH 10 or more). One gram dissolves in 3.6 ml water. Slightly sol in alc. Insol in ether, chloroform.
     
    Therap-Cat: Antibacterial.
    Therap-Cat-Vet: Antibacterial.
    Keywords: Antibacterial (Synthetic); Sulfonamides.