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Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3®
CAS No 128517-07-7 , Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3®
Name:
Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3®
Synonyms:
FK 228;2-Oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricosane, cyclic peptidederiv.;Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3® FR 901228; Chromadax;5)-disulfide;Romidepsin;2)-disulfide, [S-(E)]-; NSC 630176; Antibiotic FR 901228;1)-lactone, cyclic (1®L-Valine,N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-,(4®
CAS Registry Number:
128517-07-7
Flash Point:
524°C
Boiling Point:
942.8°C at 760 mmHg
Density:
1.174g/cm
3
Refractive index:
1.529
Flash Point:
524°C
Molecular Weight:
0
InChI:
InChI=1/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17+,19+,20-/m0/s1
Molecular Formula:
C24H36 N4 O6 S2
Molecular Structure:
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128517-07-7 Romidepsin
Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) or/and peripheral T-cell lymphoma (PTCL) in patients who have received at least one prior systemic therapy. T...
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128517-07-7 FK-228(Romidepsin)
Unlike TSA, the active form redFK of Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively. Romidepsin is 17-23 times w...
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Tel: 1-631-6197922
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128517-07-7 Romidepsin
Romidepsin Romidepsin (FK228, depsipeptide) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively. IC50 Value: 36 nM(HDAC1); 47 nM(HDAC2) Target: HDAC Romidepsin, a selective inhibitor of histone deacetylases (HDACs), was a...
MedChemexpress LLC
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Tel: 609-228-6898
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Address: 18 Wilkinson Way, Princeton, NJ 08540, USA Princeton,New JerseyUnited States
128517-07-7 FR-901228
Advanced Technology & Industrial Co., Ltd.
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Tel: (852) 2390 2293/ (852) 2394 5546
Fax: (852) 2789 8314
Address: Unit B, 1/F., Cheong Shing Bldg.,
17 Walnut St., Tai Kok Tsui, Kln,
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128517-07-7 Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3®5)-disulfide
Tianjin Youlong Science&Technology development Co., Ltd.
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Address: Room 505 Building D, No.6 Zhuyuan Road, Huayuan High-tech null,nullChina
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![CAS No:128517-07-7 Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3®](/structure/cas-128/128517-07-7.png)
