Home > Name List By 4 > 4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid

CAS No 13739-02-1 , 4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid

  • Name: 4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid
  • Synonyms: Diacereine [French]; 13739-02-1;Diacerein; Diacereinum [Latin]; 4,5-Diacetylrhein; Fisiodar; Diacetylrhein; Diacerhein;4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid; Artrodar;
  • CAS Registry Number:
  • Density: 1.491 g/cm3
  • Refractive index: 1.634
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 237-310-2
  • Molecular Weight: 368.29378
  • InchiKey: TYNLGDBUJLVSMA-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H12O8/c1-8(20)26-13-5-3-4-11-15(13)18(23)16-12(17(11)22)6-10
    (19(24)25)7-14(16)27-9(2)21/h3-7H,1-2H3,(H,24,25)
  • Risk Statements: S26;S36
  • Molecular Formula: C19H12O8
  • Molecular Structure:CAS No:13739-02-1 4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid

Related products

Search by region :

Select to

13739-02-1 diacerein

Contact Supplier

13739-02-1 Diacerein

  • Italy Icrom SpA [Manufacturers]
  • Tel: +39-(39)-6041742
  • Fax: +39-(39)-6040836
  • Address: via delle Arti, 33, Concorezzo, Milano 20049, null,nullItaly
Contact Supplier

13739-02-1 Diacerein

  • China Plamed Science Technology Inc. [Manufacturers]
  • Tel: +86-(29)-88352080
  • Fax: +86-(29)-88352022
  • Address: 35#, Tangyan Road, High-Tech Industries Development Zone, Xian, Shaanxi, Xi'an,ShaanxiChina
Contact Supplier

13739-02-1 diacerein

  • China Zhongxin Innova Laboratories [Manufacturers]
  • Tel: +86-(22)-25295002
  • Fax: +86-(22)-25295002
  • Address: 21, 10th Avenue, Teda, Tianjin 300457, Tianjin,TianjinChina
Contact Supplier

13739-02-1 diacerein

Contact Supplier

13739-02-1 diacerein

  • China Xi’an Refine Biology Co.,Ltd null
  • Tel: 13572488113
  • Fax: 86-29-87259649
  • Address: Room 10N, Winner Plaza, Wuwei Cross, Zhuque Road, xi`an,shaanxiChina
Contact Supplier

13739-02-1 diacerein

  • China YaLe chemical Co.ltd. [Manufacturers]
  • Tel: +86-138-98656361
  • Fax: +86-736-6613852
  • Address: HuNan province Chang De,HuNanChina
Contact Supplier

13739-02-1 diacerein

  • China Xian App-Chem Bio (Tech) Co., Ltd. [Manufacturers]
  • Tel: +86-29-88327527 ext.805
  • Fax: +86-29-88346302
  • Address: C601,Gazelle Valley,No.69 Jinye RD.,Xi'an,710077,China Xi'an,ShaanxiChina
Contact Supplier

13739-02-1 diacerein

Contact Supplier

13739-02-1 Diacerein

  • China Jiangyin Sanyi Chemical Co., Ltd. null
  • Fax: +86-510-86578598
  • Address: Qiaohua Road, Qiaoqi Town, Jiangyin City, Jiangsu(the North Side of Yanjiang Expressway) null,nullChina
Contact Supplier

Select to

7/9
Previous 1 2 3 4 5 6 7 8 9 Next
References of 4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid
Title: Diacerein
CAS Registry Number: 13739-02-1
CAS Name: 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid
Synonyms: 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic acid diacetate; 1,8-diacetoxy-3-carboxyanthraquinone; diacerhein; diacetylrhein; DAR
Manufacturers' Codes: SF-277
Trademarks: Artrodar (Proter); Fisiodar (Abiogen)
Molecular Formula: C19H12O8
Molecular Weight: 368.29
Percent Composition: C 61.96%, H 3.28%, O 34.75%
Literature References: Diacetyl derivative of rhein, q.v. Demonstrates anti-arthritic activity without inhibiting prostaglandin synthesis. Prepn: A. Tschirch, K. Heuberger, Arch. Pharm. 240, 596 (1902); V. K. Murty et al., Tetrahedron 23, 515 (1967). Effect on prostaglandin release: P. Pomarelli et al., Farmaco Ed. Sci. 35, 836 (1980). Inhibition of proteases: L. Raimondi et al., Pharmacol. Res. Commun. 14, 103 (1982). Use in arthritis: C. A. Friedmann, DE 2711493; idem, US 4244968 (1977, 1981 both to Proter). Preliminary clinical study in osteoarthritis: A. G. Kay et al., Curr. Med. Res. Opin. 6, 548 (1980). Use in multiple sclerosis, amyotrophic lateral sclerosis: C. A. Friedmann, US 4346103 (1982); idem, JP Kokai 83 225015 (1983 to Proter), C.A. 100, 144991e (1984). Clinical trial in osteoarthritis: S. Adami et al., Clin. Ter. 112, 439 (1985).
Properties: Yellow plates from acetic acid, mp 217-218°.
Melting point: mp 217-218°
Therap-Cat: Antiarthritic.
Keywords: Antiarthritic/Antirheumatic.