Home > Name List By other > (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl] methyl]amino]butanoic acid China

CAS No 137862-53-4 , (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]
methyl]amino]butanoic acid Search by region : China

  • Name: (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]
    methyl]amino]butanoic acid
  • Synonyms: Miten;(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]
    methyl]amino]butanoic acid; Tareg; Valsarran; Provas; Vals; Nisis; Kalpress; 137862-53-4;Diovan;
  • CAS Registry Number:
  • Transport: 10kgs
  • Melting Point: 116-117 ºC
  • Density: 1.212 g/cm3
  • Safety Statements: 26-37/39
  • Hazard Symbols: Xi: Irritant;
  • Molecular Weight: 435.51876
  • InchiKey: ACWBQPMHZXGDFX-QFIPXVFZSA-N
  • InChI: InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18
    (14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,
    15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
  • Risk Statements: 36/37/38
  • Molecular Formula: C24H29N5O3
  • Molecular Structure:CAS No:137862-53-4 (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]<br />methyl]amino]butanoic acid

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137862-53-4 3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid

  • Quick Details ProName: High quality GMP/EP/BP/ISO/CP Valsartan CasNo: 137862-53-4 Molecular Formula: C24H29N5O3 Appearance: White or off white powder Application: Valsartan is used clinical for receptor agagonist AT1,has good effect to the different ...
  • China Zhuzhou Center Biology Technology Co.,Ltd [Trading Company]
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  • Address: Meidi zhuzhou,nullChina
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137862-53-4 Valsartan

  • Synonym:3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid CAS: 137862-53-4;137863-60-6 Assay:99% M.F:C24H29N5O3 M.W:435.52 MP:116-117 deg C BP:684.9 °C at 760 mmHg Density:1.212 g/cm3 Appearance: white crystal p...
  • China Hubei Yuancheng Gongchuang Technology Co.,Ltd [Manufacturer]
  • Tel: 86-027-50756226
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China wuhan,HubeiChina
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137862-53-4 Valsartan

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137862-53-4 Valsartan

  • "Chemical Name: Valsartan Molecular Formula: C24H29N5O3 Formula Weight: 435.5188 CAS NO.: 137862-53-4 Purity:99% Characteristics:white or white crystalline powder Quality standard: USP Packaging: 25K g/drum Usage:it's used for various types of hypert...
  • Min. Order: 100
  • FOB Price: USD1 - 1.5 /
  • China Wuhan Xinzekang Chemical Co.,Ltd [Manufacturer]
  • Tel: 86-027-87886092
  • Fax: 86-027-87886092
  • Address: No. 209, Xiongchu Ave,Hongshan District,Wuhan,Hubei,430070, China wuhan,HubeiChina
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137862-53-4 Valsartan

  • CAS NO.:137862-53-4 Appearance:white or almost white crytalline powder Packing:cardboard drum 25kg/pail Usage: Using compose the medicine of new sartan resist hypertension.
  • Min. Order: 1000
  • FOB Price: USD1 - 1000 /
  • China Hubei Xinzhogrong Pharmaceutical CO.,LTD. [Manufacturer, Trading Company]
  • Tel: 86-0576-88698107
  • Address: The Park of Longgan Huanggan,HubeiChina
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137862-53-4 Valsartan

  • China Simag Chemicals [Manufacturer]
  • Tel: +86 592 2680277
  • Fax: +86 592 2680237
  • Address: Simag Chemicals
    A-9D Atlantic sea view city,
    No.9 Hubin West Rd.,
    Xiamen China. null,nullChina
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137862-53-4; 137863-60-6 Valsartan

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137862-53-4 VALSARTAN

  • China Shanghai Sinch Parmaceuticals Tech. Co. Ltd. [Manufacturer]
  • Tel: +86-21-54097791/ +86-13386129050 (mobile)
  • Fax: +86-21-54096319
  • Address: SINCH Pharmaceuticals Tech. Co., Ltd
    Bldg 2, 237 Xitai Rd, Xuhui district,
    Shanghai 200232, China null,nullChina
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137862-53-4 Valsartan

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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137862-53-4 Valsartan

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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References of (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]
methyl]amino]butanoic acid
Title: Valsartan
CAS Registry Number: 137862-53-4
CAS Name: N-(1-Oxopentyl)-N-[[2¢-(1H-tetrazol-5-yl)[1,1¢-biphenyl]-4-yl]methyl]-L-valine
Synonyms: N-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-N-valeryl-L-valine; (S)-N-(1-carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2¢-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]amine
Manufacturers' Codes: CGP-48933
Trademarks: Diovan (Novartis); Tareg (Novartis)
Molecular Formula: C24H29N5O3
Molecular Weight: 435.52
Percent Composition: C 66.19%, H 6.71%, N 16.08%, O 11.02%
Literature References: Nonpeptide angiotensin II AT1-receptor antagonist. Prepn: P. Bühlmayer et al., EP 443983; eidem, US 5399578 (1991, 1995 both to Ciba Geigy); idem et al., Bioorg. Med. Chem. Lett. 4, 29 (1994). Pharmacological profile: L. Criscione et al., Br. J. Pharmacol. 110, 761 (1993). HPLC determn in human plasma: A. Sioufi et al., J. Liq. Chromatogr. 17, 2179 (1994). Clinical pharmacology: P. Müller et al., Eur. J. Clin. Pharmacol. 47, 231 (1994). Clinical comparison with captopril, q.v., in high risk patients following myocardial infarction: M. A. Pfeffer et al., N. Engl. J. Med. 349, 1893 (2003). Review of pharmacology and clinical experience in heart failure: R. Latini et al., Expert Opin. Pharmacother. 5, 181-193 (2004).
Properties: Crystals from diisopropyl ether, mp 116-117°. Partition coefficient (n-octanol/aq phosphate buffer): 0.033. Sol in water at 25°.
Melting point: mp 116-117°
Log P: Partition coefficient (n-octanol/aq phosphate buffer): 0.033
Therap-Cat: Antihypertensive.
Keywords: Angiotensin II Receptor Antagonist; Antihypertensive; Biphenyltetrazole Derivatives.