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CAS No 14417-88-0 , 9,12-Octadecadienamide,N-(1-phenylethyl)-, (9Z,12Z)-

  • Name: 9,12-Octadecadienamide,N-(1-phenylethyl)-, (9Z,12Z)-
  • Synonyms: 9,12-Octadecadienamide,N-(1-phenylethyl)-, (9Z,12Z)-; AC 223; Artes; N-(DL-a-Methylbenzyl) linoleamide; Linoleamide, N-(a-methylbenzyl)- (8CI); N-(a-Methylbenzyl)linoleamide;Melinamide; MBLA; DL-a-Methylbenzyl linoleamide;9,12-Octadecadienamide,N-(1-phenylethyl)-, (Z,Z)-; DL-N-(a-Methylbenzyl)linoleamide;
  • CAS Registry Number:
  • Flash Point: 333.3°C
  • Boiling Point: 537.4°Cat760mmHg
  • Density: 0.928g/cm3
  • Refractive index: 1.506
  • Safety Statements: Moderately toxic by intraperitoneal route. Low toxicity by ingestion and subcutaneous routes. When heated to decomposition it emits toxic vapors of NOx.
  • Flash Point: 333.3°C
  • Molecular Weight: 0
  • InChI: InChI=1/C26H41NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23-26(28)27-24(2)25-21-18-17-19-22-25/h7-8,10-11,17-19,21-22,24H,3-6,9,12-16,20,23H2,1-2H3,(H,27,28)/b8-7+,11-10+
  • Molecular Formula: C26H41NO
  • Molecular Structure:CAS No:14417-88-0 9,12-Octadecadienamide,N-(1-phenylethyl)-, (9Z,12Z)-

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References of 9,12-Octadecadienamide,N-(1-phenylethyl)-, (9Z,12Z)-
Title: Melinamide
CAS Registry Number: 14417-88-0
CAS Name: (Z,Z)-N-(1-Phenylethyl)-9,12-octadecadienamide
Synonyms: N-(a-methylbenzyl)linoleamide; MBLA
Manufacturers' Codes: AC-223
Trademarks: Artes (Sumitomo)
Molecular Formula: C26H41NO
Molecular Weight: 383.61
Percent Composition: C 81.41%, H 10.77%, N 3.65%, O 4.17%
Literature References: Linoleic acid derivative. Prepn and use in lowering blood cholesterol levels: FR 1476596; T. Seki et al., US 3621043 (1967, 1971 both to Sumitomo). Physical properties and effect on cholesterol levels in rabbits: K. Toki et al., J. Atheroscler. Res. 7, 708 (1967). Comparative activity of melinamide and its optical isomers: H. Fukushima, K. Nakatani, ibid. 9, 65 (1969); H. Fukushima et al., ibid. 10, 403 (1969). Mechanism of action studies: D. Kritchevsky, S. A. Tepper, Arzneim.-Forsch. 21, 1024 (1971); D. Kritchevsky et al., Lipids 12, 16 (1977); K. Natori et al., Jpn. J. Pharmacol. 42, 517 (1986). Metabolism: A. Hirohashi et al., Xenobiotica 6, 329 (1976).
Properties: Oil. mp <4°. bp0.03 200-215°; bp0.07 200-204°. nD23 1.5050; nD30 1.4863. Saponification value 0.9. Iodine value 127.0.
Melting point: mp <4°
Boiling point: bp0.03 200-215°; bp0.07 200-204°
Index of refraction: nD23 1.5050; nD30 1.4863
Therap-Cat: Antilipemic.
Keywords: Antilipemic.