Home > Name List By n > N, N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine

CAS No 154323-57-6 , N,
N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine

  • Name: N,
    N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine
  • Synonyms: Spectrum_001884;N,
    N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine; CHEBI:520985; Almotriptan (USAN); Spectrum3_001006; Almogran;Axert; AC1L3WYP; Spectrum2_000498; 154323-57-6;
  • CAS Registry Number:
  • Density: 1.27 g/cm3
  • Molecular Weight: 335.4643
  • InchiKey: WKEMJKQOLOHJLZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H25N3O2S/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23
    (21,22)20-8-3-4-9-20/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3
  • Molecular Formula: C17H25N3O2S
  • Molecular Structure:CAS No:154323-57-6 N,<br />N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine

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References of N,
N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine
Title: Almotriptan
CAS Registry Number: 154323-57-6
CAS Name: 1-[[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine
Synonyms: 1-[[3-(2-dimethylaminoethyl)-5-indolyl]methanesulphonyl]pyrrolidine
Manufacturers' Codes: LAS-31416
Molecular Formula: C17H25N3O2S
Molecular Weight: 335.46
Percent Composition: C 60.87%, H 7.51%, N 12.53%, O 9.54%, S 9.56%
Literature References: Serotonin 5HT1B/1D-receptor agonist. Prepn: D. F. Forner et al., WO 9402460; eidem, US 5565447 (1994, 1996 both to Almirall). Clinical pharmacokinetics: J. C. Fleishaker et al., Clin. Pharmacol. Ther. 67, 498 (2000). Review of pharmacology: F. Kamali, Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs 2, 197-202 (2000); of clinical studies: D. W. Dodick, Expert Opin. Pharmacother. 4, 1157-1163 (2003).
 
Derivative Type: Maleate
CAS Registry Number: 181183-52-8
Manufacturers' Codes: PNU-180638E
Trademarks: Almogran (Almirall); Axert (Pharmacia & Upjohn)
Molecular Formula: C17H25N3O2S.C4H6O5
Molecular Weight: 469.55
Percent Composition: C 53.72%, H 6.65%, N 8.95%, O 23.85%, S 6.83%
Properties: White to slightly yellow crystalline powder; sol in water.
 
Therap-Cat: Antimigraine.
Keywords: Antimigraine; Serotonin Receptor Agonist.