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CAS No 15500-66-0 , Pancuronium bromide

  • Name: Pancuronium bromide
  • Synonyms: 2-beta,16-beta-bis(1-methylpiperidinio)androstane-3-alpha,17-beta-diol 3-alpha,17-beta-di(acetate) dibromide;Pancuronium bromide;1,1'-[(2b,3a,5a,16b,17b)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 214 - 217
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 239-532-5
  • Molecular Weight: 732.68
  • InChI: InChI=1/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
  • Risk Statements: R22
  • Molecular Formula: C35H60Br2N2O4
  • Molecular Structure:CAS No:15500-66-0 Pancuronium bromide
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15500-66-0 PANCURONIUM BROMIDE

  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
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15500-66-0 Pancuronium Bromide

  • China IFFECT CHEMPHAR CO., LTD. null
  • Tel: 0086 755-83761619 83760606
  • Fax: +86-25- 84270111
  • Address: 15A,Changfa Center, Building B ,No. 300,East Zhongshan Road,Baixia District,Nanjing,210002, P.R.China. Nanjing,JiangshuChina
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15500-66-0 Pancuronium Bromide

  • United States Tocris Bioscience [Manufacturers]
  • Tel: +1-(800)-421-3701
  • Fax: +1-(800)-483-1993
  • Address: 16144 Westwoods Business Park, Ellisville, Missouri 63021, null,MissouriUnited States
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15500-66-0 Pancuronium Bromide

  • China Jiangsu Guotai International Group null
  • Fax: +86-512-58671120
  • Address: 10-11/F, Guotai Bldg, 43 Renmin Road, Zhangjiagang, Jiangsu Province, China 215600. null,nullChina
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15500-66-0 PANCURONIUM BROMIDE

  • China NINGBO INNO PHARMCHEM CO.,LTD. [Manufacturer]
  • Tel: 86-574-27787870 / 87319282
  • Fax: 86-574-27912196 / 56877908
  • Address: NINGBO INNO PHARMCHEM CO.,LTD.
    Address: 11F,298 WEST ZHONGSHAN RD.
    NINGBO 315000 CHINA null,nullChina
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15500-66-0 PANCURONIUM DIBROMIDE

  • China BEIJING SHLHT CHEMICAL TECHNOLOGY [Manufacturer]
  • Tel: +8610 68835641/ +8610 68835642
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  • Address: No. 5-6-402 Yangzhuangzhongqu,
    Shijingshan District
    Beijing China 100043 null,nullChina
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15500-66-0 Pancuronium bromide

  • China Rota Pharm and Chem Co., Ltd. null
  • Fax: +86-571-87918114
  • Address: Room 401,Hangzhou Friendship Plaza,No.74 Bbaochu Road, Hangzhou, China null,nullChina
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References of Pancuronium bromide
Title: Pancuronium Bromide
CAS Registry Number: 15500-66-0
CAS Name: 1,1¢-[(2b,3a,5a,16b,17b)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis[1-methylpiperidinium] dibromide
Synonyms: 1,1¢-(3a,17b-dihydroxy-5a-androstan-2b,16b-ylene)bis[1-methylpiperidinium] dibromide diacetate; 3a,17b-diacetoxy-2b,16b-dipiperidino-5a-androstane dimethobromide; 2b,16b-dipiperidino-5a-androstane-3a,17b-diol diacetate dimethobromide; poncuronium bromide (rescinded USAN)
Manufacturers' Codes: NA-97; Org-NA-97
Trademarks: Mioblock (Sankyo); Pavulon (Organon)
Molecular Formula: C35H60Br2N2O4
Molecular Weight: 732.67
Percent Composition: C 57.38%, H 8.25%, Br 21.81%, N 3.82%, O 8.73%
Literature References: Aminosteroid, competitive neuromuscular blocker. Prepn: W. R. Buckett et al., Chim. Ther. 2, 186 (1967); eidem, J. Med. Chem. 16, 1116 (1973). Structural studies: Savage et al., J. Chem. Soc. B 1971, 410. Structure-activity correlation: Waser, Anaesthesist 20, 23 (1971). Pharmacology: W. R. Buckett, I. L. Bonta, Fed. Proc. 25, 718 (1966); W. R. Buckett et al., Br. J. Pharmacol. Chemother. 32, 671 (1968); I. L. Bonta et al., Eur. J. Pharmacol. 4, 83, 303 (1968). Comparative study of neuromuscular blocking and vagolytic effect: S. L. Son et al., Anesthesiology 55, 12 (1981). Review: Speight, Avery, Drugs 4, 163-226 (1972).
Properties: Odorless crystals with bitter taste, mp 215°. One gram dissolves in 30 parts chloroform, one part water (20°). LD50 in mice (mg/kg): 0.047 i.v.; 0.152 i.p.; 0.167 s.c.; 21.9 orally; in rats, rabbits: 0.153, 0.016 i.v. (Buckett, 1968).
Melting point: mp 215°
Toxicity data: LD50 in mice (mg/kg): 0.047 i.v.; 0.152 i.p.; 0.167 s.c.; 21.9 orally; in rats, rabbits: 0.153, 0.016 i.v. (Buckett, 1968)
Therap-Cat: Neuromuscular blocking agent.
Therap-Cat-Vet: Neuromuscular blocking agent.
Keywords: Neuromuscular Blocking Agent; Nondepolarizing Agents.