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CAS No 15500-66-0 , Pancuronium bromide

  • Name: Pancuronium bromide
  • Synonyms: 2-beta,16-beta-bis(1-methylpiperidinio)androstane-3-alpha,17-beta-diol 3-alpha,17-beta-di(acetate) dibromide;Pancuronium bromide;1,1'-[(2b,3a,5a,16b,17b)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 214 - 217
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 239-532-5
  • Molecular Weight: 732.68
  • InChI: InChI=1/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
  • Risk Statements: R22
  • Molecular Formula: C35H60Br2N2O4
  • Molecular Structure:CAS No:15500-66-0 Pancuronium bromide
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15500-66-0 pancuronium bromide

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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15500-66-0 PANCURONIUM BROMIDE

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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15500-66-0 pancuronium bromide

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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15500-66-0 pancuronium bromide

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
  • Fax: +86-21-58408291
  • Address: 1213 JunMin Road,Pudong,China ,China
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15500-66-0 Panocuronium Bromide

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15500-66-0 PANCURONIUM BROMIDE

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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15500-66-0 Pancuronium bromide

  • United States CBSCHEM LIMITED []
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 ,United States
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15500-66-0 pancuronium bromide

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15500-66-0 pancuronium bromide

  • China Hangzhou Hysen Pharma Co.,Ltd [Manufacturers]
  • Tel: 0571-89937472
  • Fax: 0571-89937386
  • Address: ROOM 808, C# Zi Jin PLAZA , NO. 701, Gu'Dun ROAD hangzhou,zhejiangChina
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15500-66-0 0693 PANCURONIUM DIBROMIDE

  • United States Tocris Bioscience [Manufacturer]
  • Tel: (800) 421-3701/ (636) 207-7651
  • Fax: (800) 483-1993 / (636) 207-7683
  • Address: Tocris Bioscience
    16144 Westwoods Business Park
    Ellisville, Missouri 63021
    USA ,United States
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References of Pancuronium bromide
Title: Pancuronium Bromide
CAS Registry Number: 15500-66-0
CAS Name: 1,1¢-[(2b,3a,5a,16b,17b)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis[1-methylpiperidinium] dibromide
Synonyms: 1,1¢-(3a,17b-dihydroxy-5a-androstan-2b,16b-ylene)bis[1-methylpiperidinium] dibromide diacetate; 3a,17b-diacetoxy-2b,16b-dipiperidino-5a-androstane dimethobromide; 2b,16b-dipiperidino-5a-androstane-3a,17b-diol diacetate dimethobromide; poncuronium bromide (rescinded USAN)
Manufacturers' Codes: NA-97; Org-NA-97
Trademarks: Mioblock (Sankyo); Pavulon (Organon)
Molecular Formula: C35H60Br2N2O4
Molecular Weight: 732.67
Percent Composition: C 57.38%, H 8.25%, Br 21.81%, N 3.82%, O 8.73%
Literature References: Aminosteroid, competitive neuromuscular blocker. Prepn: W. R. Buckett et al., Chim. Ther. 2, 186 (1967); eidem, J. Med. Chem. 16, 1116 (1973). Structural studies: Savage et al., J. Chem. Soc. B 1971, 410. Structure-activity correlation: Waser, Anaesthesist 20, 23 (1971). Pharmacology: W. R. Buckett, I. L. Bonta, Fed. Proc. 25, 718 (1966); W. R. Buckett et al., Br. J. Pharmacol. Chemother. 32, 671 (1968); I. L. Bonta et al., Eur. J. Pharmacol. 4, 83, 303 (1968). Comparative study of neuromuscular blocking and vagolytic effect: S. L. Son et al., Anesthesiology 55, 12 (1981). Review: Speight, Avery, Drugs 4, 163-226 (1972).
Properties: Odorless crystals with bitter taste, mp 215°. One gram dissolves in 30 parts chloroform, one part water (20°). LD50 in mice (mg/kg): 0.047 i.v.; 0.152 i.p.; 0.167 s.c.; 21.9 orally; in rats, rabbits: 0.153, 0.016 i.v. (Buckett, 1968).
Melting point: mp 215°
Toxicity data: LD50 in mice (mg/kg): 0.047 i.v.; 0.152 i.p.; 0.167 s.c.; 21.9 orally; in rats, rabbits: 0.153, 0.016 i.v. (Buckett, 1968)
Therap-Cat: Neuromuscular blocking agent.
Therap-Cat-Vet: Neuromuscular blocking agent.
Keywords: Neuromuscular Blocking Agent; Nondepolarizing Agents.