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CAS No 15676-16-1 , N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide

  • Name: N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
  • Synonyms: Dogmatil; Mirbanil; Misulvan; Sulpyrid; Sulpirid;N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide; Dogmatyl; Guastil; Dolmatil;Aiglonyl;
  • CAS Registry Number:
  • Melting Point: 180 - 185 C
  • Flash Point: °C
  • Boiling Point:
  • Density: 1.236g/cm3
  • Water Solubility: Insoluble
  • Safety Statements: Poison by intraperitoneal, subcutaneous and intravenous routes. Moderately toxic by ingestion. Human systemic effects by ingestion and intramuscular route: tremors, hypermotility, diarrhea and fever. Experimental reproductive effects. Used as a digestive aid and psychotropic drug. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • Hazard Symbols: UN NO.
  • Flash Point: °C
  • EINECS: 239-753-7
  • Molecular Weight: 341.42582
  • InchiKey: BGRJTUBHPOOWDU-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,
    20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)
  • Risk Statements: 36/37/38
  • Molecular Formula: C15H23N3O4S
  • Molecular Structure:CAS No:15676-16-1 N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
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15676-16-1 Sulpiride

  • Sulpiride Synonyms:Abilit;Aiglonyl Product Categories:Sulpiride;Dopamine receptor;Aromatics;Heterocycles;DOGMATYL CAS:15676-16-1 Appearance:White Solid Purity:99% Package:25kg/cardboard MF:C15H23N3O4S MW:341.43 EINECS:239-753-7 storage temp. 2-8°C Us...
  • China Raw Steroid Shop [Manufacturer, Trading Company]
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  • 15676-16-1 Sulpiride

    • Sulpiride Synonyms:Abilit;Aiglonyl Product Categories:Sulpiride;Dopamine receptor;Aromatics;Heterocycles;DOGMATYL CAS:15676-16-1 Appearance:White Solid Purity:99% Package:25kg/cardboard MF:C15H23N3O4S MW:341.43 EINECS:239-753-7 storage temp. 2-8°C Us...
    • Min. Order: 10
    • FOB Price: USDfalse - false /
    • China Raw Steroid Main Shop [Manufacturer]
    • Tel: 86-0731-22290207
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    • Address: Hunan zhuzhou,HunanChina
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    15676-16-1 SULPIRIDE

    • Synonym: SULPIRIDE 5-(AMINOSUFONYL)-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE N-((1-ETHYLPYRROLIDIN-2-YL)METHYL)-2-METHOXY-5-SULFAMOYLBENZAMIDE (RS)-(+/-)-SULPIRIDE (RS)-(+/-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBE...
    • China Hubei Yuancheng Gongchuang Technology Co.,Ltd [Manufacturer]
    • Tel: 86-027-50756226
    • Address: No.496,Zhongshan Road, Wuhan, Hubei, China wuhan,HubeiChina
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    15676-16-1 Name:Sulpiride

    • Product Name:Sulpiride CAS No:15676-16-1 Corresponding bulk drugs Sulpiride Packs the specification:25kg/barrel Quality specification: Appearance:white crystal powder Lossing on drying:NMT0.5% Purity(Titration):98.5%~101.0% Contact person: Mr.Toby E-...
    • China Zhongbei No thland Bio-Chem Indust y Co., Ltd. [Manufacturer]
    • Tel: 86-452-6055586
    • Fax: 86-452-6197939
    • Address: 5F, C Liandalijing Bulding,No 259 Xinjiang Road, Jianhua District, Qiqiha'er City, Heilongjiang Province, China Qiqihaer,HeilongjiangChina

    15676-16-1 (+-)-sulpiride

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    15676-16-1 Sulpiride

    • Sulpiride MF: C15H23N3O4S MW: 341.43 CAS: 15676-16-1 Spec: Appearance: off-white crystal Assay: 98.5%-101.0% EP5.0 Package:25kg/drum
    • Min. Order: 1
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    • China China Skyrun Industrial CO.,Ltd [Manufacturer]
    • Tel: 86-576-84768865
    • Address: Chemical Development Zone nanjing,JiangsuChina
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    15676-16-1 Sulpiride 15676-16-1annie@bhdatong.com

    • Sulpiride 15676-16-1annie@bhdatong.com Name Sulpiride CAS : 15676-16-1 Purity (HPLC) : more than 99% Formula : C15H23N3O4S Molecular Weight: 341.43 Dry weightlessness: below 0.5% Appearance: White Powder Use : Easy for central check the spit will med...
    • China Hubei Datong Bio-Chemical Technology Co., Ltd. [Manufacturer]
    • Tel: 86-27-88888888
    • Address: Gold Bridge of Development Zone wuhan ,HubeiChina
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    15676-16-1 Sulpiride

    • United States LGM Pharma [Manufacturer]
    • Tel: 561-981-9994
    • Fax: 561-892-0580
    • Address: 922 Clint Moore Road
      Boca Raton, FL 33487 ,United States
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    15676-16-1 (S)-(-)-Sulpiride

    • (S)-(-)-Sulpiride, 99.9%
    • Switzerland BIOTREND Chemicals AG [Manufacturer]
    • Tel: +41 44 805 76 76
    • Fax: +41 44 805 76 77
    • Address: BIOTREND Chemicals AG
      Unterdorfstr. 21b
      CH-8602 Wangen/Zuerich
      Switzerland ,Switzerland
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    15676-16-1 Levosulpiride

    • Levosulpiride
    • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
    • Tel: +86-28-88007744
    • Fax: +86-28-85193812
    • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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    References of N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
    Title: Sulpiride
    CAS Registry Number: 15676-16-1
    CAS Name: 5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
    Synonyms: N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide; N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-sulfamoylbenzamide
    Trademarks: Abilit (Sumitomo); Aiglonyl (Fumouze); Coolspan (Hishiyama); Dobren (Ravizza); Dogmatil (Synthelabo); Dogmatyl (Fujisawa); Dolmatil (Lorex); Guastil (Uriach); Meresa (Dolorgiet); Miradol (Mitsui); Mirbanil (Boehringer, Ing.); Misulvan (Bernabo); Neogama (Hormosan); Omperan (Taiho); Pyrikappl (Isei); Sernevin (Toho Yakuhin); Splotin (Taiyo); Sulpitil (Tillotts); Sulpor (Rosemont); Sursumid (Labif); Synédil (Beytout); Trilan (Esseti)
    Molecular Formula: C15H23N3O4S
    Molecular Weight: 341.43
    Percent Composition: C 52.77%, H 6.79%, N 12.31%, O 18.74%, S 9.39%
    Literature References: Dopamine D2 and D3-receptor antagonist. Prepn: C. S. Miller et al., US 3342826 (1964 to Soc. d'Etudes Sci. Ind. de l'Ile-de-France); of l-form: F. Mauri, DE 2903891 (1979 to Ravizza), C.A. 91, 211259h (1979). Crystal structure: L. Y. Y. Ma et al., Acta Crystallogr. B38, 2861 (1982). Mechanism of action: P. Jenner et al., J. Pharm. Pharmacol. 32, 39 (1980). Structure-activity study: P. Dostert et al., Eur. J. Med. Chem. - Chim. Ther. 17, 437 (1982). Physical properties: D. Pitrè, E. Valoti, Arch. Pharmacol. 320, 859 (1987). Comprehensive description: D. Pitrè et al., Anal. Profiles Drug Subs. 17, 607-641 (1988). Review of clinical efficacy in psychiatry: A. J. Wagstaff et al., CNS Drugs 2, 313-333 (1994); of levosulpiride in gastroenterology: M. Guslandi, Curr. Ther. Res. 53, 484-501 (1993).
    Properties: White, odorless crystalline powder, mp 178-180°. Sparingly sol in methanol. Practically insol in water, ether, chloroform, benzene. pKa1 9.00, pKa2 10.19. [a]D25 -66.8° (c = 0.5 in DMF). LD50 in mice (mg/kg): 170 i.p.; 2250 orally (Dostert).
    Melting point: mp 178-180°
    pKa: pKa1 9.00, pKa2 10.19
    Optical Rotation: [a]D25 -66.8° (c = 0.5 in DMF)
    Toxicity data: LD50 in mice (mg/kg): 170 i.p.; 2250 orally (Dostert)
     
    Derivative Type: l-Form
    CAS Registry Number: 23672-07-3
    Synonyms: Levosulpiride; S(-)-sulpiride
    Trademarks: Levobren (Knoll); Levopraid (Ravizza)
    Properties: Monomorphic crystalline solid, mp 185-187°.
    Melting point: mp 185-187°
     
    Therap-Cat: Antipsychotic; antidepressant; antiemetic.
    Keywords: Antidepressant; Antiemetic; Antipsychotic; Benzamides; Dopamine Receptor Antagonist.