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CAS No 15686-51-8 , Clemastine fumarate

  • Name: Clemastine fumarate
  • CAS Registry Number:
  • Flash Point: 211°C
  • Boiling Point: 425.2°Cat760mmHg
  • Density: 1.097g/cm3
  • Refractive index: 1.553
  • Flash Point: 211°C
  • EINECS: 239-055-2
  • Molecular Weight: 459.96
  • InChI: InChI=1/C21H26ClNO/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-/m1/s1
  • Molecular Formula: C21H26ClNO
  • Molecular Structure:CAS No:15686-51-8 Clemastine fumarate
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15686-51-8 Clemastin

  • Clemastin
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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15686-51-8 CLEMASTINUM

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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15686-51-8 Clemastine fumarate

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15686-51-8 Clemastine Fumarate

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15686-51-8 Clemastine

  • Clemastine
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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15686-51-8 Clemastine

  • Clemastine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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15686-51-8 Clemastine

  • Clemastine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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15686-51-8 Clemastine fumarate

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
  • Fax: +86-21-58408291
  • Address: 1213 JunMin Road,Pudong,China ,China
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15686-51-8 Clemastine

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15686-51-8 Clemastine

  • India Manus Aktteva []
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, ,India
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References of Clemastine fumarate
Title: Clemastine
CAS Registry Number: 15686-51-8
CAS Name: (2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine
Synonyms: (+)-2-[2-[(p-chloro-a-methyl-a-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine; 1-methyl-2-[2-(a-methyl-p-chlorobenzhydryloxy)ethyl]pyrrolidine; 1-methyl-2-[2-(methyl-p-chlorodiphenylmethyloxy)ethyl]pyrrolidine; meclastine
Molecular Formula: C21H26ClNO
Molecular Weight: 343.89
Percent Composition: C 73.34%, H 7.62%, Cl 10.31%, N 4.07%, O 4.65%
Literature References: Prepn: GB 942152 (1963 to Sandoz). Synthesis and abs config: A. Ebn?ther, H. P. Weber, Helv. Chim. Acta 59, 2462 (1976). Pharmacology and toxicology of the hydrogen fumarate: Weidmann et al., Boll. Chim. Farm. 106, 467 (1967). HPLC determn in plasma: V. Horváth et al., J. Chromatogr. B 816, 153 (2005).
Properties: Free base, bp0.02 154°. nD22 1.5582. [a]D20 +33.6° (ethanol).
Boiling point: bp0.02 154°
Optical Rotation: [a]D20 +33.6° (ethanol)
Index of refraction: nD22 1.5582
 
Derivative Type: Hydrogen fumarate
CAS Registry Number: 14976-57-9
Manufacturers' Codes: HS-592
Trademarks: Aloginan (Tobishi); Alphamin (SS Pharm.); Anhistan (Nippon Zoki); Fuluminol (Tatsumi); Inbestan (Maruko); Kinotomin (Toa Eiyo); Lacretin (Tokyo Tanabe); Lecasol (Kaken); Maikohis (Nichiiko); Mallermin-F (Taiyo); Marsthine (Towa Yakuhin); Masletine (Sioe); Piloral (Nippon Kayaku); Reconin (Toyama); Tavegil (Novartis); Tavegyl (Novartis); Tavist (Novartis); Telgin-G (Takeda); Trabest (Hoei); Xolamin (Sanko)
Molecular Formula: C25H30ClNO5
Molecular Weight: 459.96
Percent Composition: C 65.28%, H 6.57%, Cl 7.71%, N 3.05%, O 17.39%
Properties: mp 177-178°. [a]D21 +16.9° (methanol). LD50 in mice, rats (mg/kg): 730, 3550 orally; 43, 82 i.v. (Weimann).
Melting point: mp 177-178°
Optical Rotation: [a]D21 +16.9° (methanol)
Toxicity data: LD50 in mice, rats (mg/kg): 730, 3550 orally; 43, 82 i.v. (Weimann)
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Aminoalkylethers.