Home > Name List By other > (6R, 7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS No 15686-71-2 , (6R,
7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-
azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

  • Name: (6R,
    7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-
    azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Synonyms: Cephalexinum; Cephalexine; Cepastar; Cephacillin; Ceporexin;Cefalexin; Cepexin; Cefaloto; Ceporexine;(6R,
    7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-
    azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
  • CAS Registry Number:
  • Density: 1.5g/cm3
  • Safety Statements: R42/43
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 239-773-6
  • Molecular Weight: 347.38888
  • InchiKey: ZAIPMKNFIOOWCQ-UEKVPHQBSA-N
  • InChI: InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)
    10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,
    11-,15-/m1/s1
  • Risk Statements: S22;S36/37;S45
  • Molecular Formula: C16H17N3O4S
  • Molecular Structure:CAS No:15686-71-2 (6R,<br />7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-<br />azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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15686-71-2 Cephalexin

  • Cephalexin
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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15686-71-2 Cephalexin

  • Cephalexin, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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15686-71-2 Cephalexin

  • Cephalexin
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,nullChina
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15686-71-2 Cephalexin

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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15686-71-2 Homprenorphine

  • Homprenorphine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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15686-71-2 Cephalexin

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15686-71-2 Cephalexin

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15686-71-2 Cephalexin

  • China China Langchem Inc. null
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, null,nullChina
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15686-71-2 Cephalexin

  • Cephalexin, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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15686-71-2 Cephalexin

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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References of (6R,
7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-
azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Title: Cephalexin
CAS Registry Number: 15686-71-2
CAS Name: (6R,7R)-7-[[(2R)-Aminophenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: 7-(D-a-aminophenylacetamido)desacetoxycephalosporanic acid; 7-(D-2-amino-2-phenylacetamido)-3-methyl-D3-cephem-4-carboxylic acid
Trademarks: Cefadros (Proter); Cefaloto (Lifepharma); Cefanex (Apothecon); Cefaseptin (Chassot); Cex (Nippon Glaxo); Derantel (Nippon Chemiphar); Efalexin (Maipe); Farexin (Lafare); Fergon 500 (Alfar); Garasin (Wakamoto); Ibilex (IBI); Iwalexin (Iwaki); Larixin (Toyama); Lexibiotico (Llano); Llonexina (Castillon); Madlexin (Meiji); Mamalexin (Showa Yakuhin); Mecilex (C.E.P.A.); Ohlexin (Ohta); Oracocin (Tobishi); Rinesal (Kissei); Sencephalin (Takeda); Sintolexyn (ISF-Italseber); Syncl (Toyo Jozo); Taicelexin (Taiyo); Tokiolexin (Isei); Xahl (SS Pharm.)
Molecular Formula: C16H17N3O4S
Molecular Weight: 347.39
Percent Composition: C 55.32%, H 4.93%, N 12.10%, O 18.42%, S 9.23%
Literature References: Semi-synthetic cephalosporin antibiotic. Prepn: R. B. Morin, B. G. Jackson, US 3275626; US 3507861 (1966, 1970 both to Lilly); Ryan et al., J. Med. Chem. 12, 310 (1969). Pharmacology and toxicology: Muggleton et al., Antimicrob. Agents Chemother. 1968, 353; Kind et al., Welles et al., ibid. 361, 489. Comprehensive description: L. P. Marrelli, Anal. Profiles Drug Subs. 4, 21-46 (1975). Clinical pharmacology, efficacy, adverse reactions: Postgrad. Med. J. 59, Suppl. 5, 1-56 (1983).
Properties: Crystals. uv max: 260 nm (e 7750). pKa 5.2, 7.3.
pKa: pKa 5.2, 7.3
Absorption maximum: uv max: 260 nm (e 7750)
 
Derivative Type: Monohydrate
CAS Registry Number: 23325-78-2
Trademarks: Cefa-Iskia (Iskia); Cefibacter (Rubio); Ceporex (GSK); Ceporexin (GSK); Keforal (Lilly); Keflet (Lilly); Keflex (Lilly); Oracef (Lilly); Ortisporina (Turro); Sartosona (Sastre); Servispor (Servipharm)
Properties: LD50 in mice, rats (g/kg): 1.6-4.5, >5.0 orally; 0.4-1.3, >3.7 i.p. (Welles).
Toxicity data: LD50 in mice, rats (g/kg): 1.6-4.5, >5.0 orally; 0.4-1.3, >3.7 i.p. (Welles)
 
Derivative Type: Monohydrochloride monohydrate
CAS Registry Number: 105879-42-3
Manufacturers' Codes: LY-061188
Trademarks: Keftab (Lilly)
Molecular Formula: C16H17N3O4S.HCl.H2O
Molecular Weight: 401.87
Percent Composition: C 47.82%, H 5.02%, N 10.46%, O 19.91%, S 7.98%, Cl 8.82%
 
Derivative Type: Sodium salt
CAS Registry Number: 38932-40-0
Trademarks: Alfaspoven (Alfa)
Molecular Formula: C16H16N3NaO4S
Molecular Weight: 369.37
Percent Composition: C 52.03%, H 4.37%, N 11.38%, Na 6.22%, O 17.33%, S 8.68%
 
Derivative Type: Pivalate ester see Pivcefalexin
 
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.