Home > Name List By 5 > 5-[(2Z)-2-(3-carboxy-4-oxocyclohexa-2, 5-dien-1-ylidene)hydrazinyl]-2-hydroxybenzoic acid

CAS No 15722-48-2 , 5-[(2Z)-2-(3-carboxy-4-oxocyclohexa-2,
5-dien-1-ylidene)hydrazinyl]-2-hydroxybenzoic acid

  • Name: 5-[(2Z)-2-(3-carboxy-4-oxocyclohexa-2,
    5-dien-1-ylidene)hydrazinyl]-2-hydroxybenzoic acid
  • Synonyms: Azodisal; Olsalazina; 3,3'-Azobis(6-hydroxybenzoic acid); 15722-48-2;5-[(2Z)-2-(3-carboxy-4-oxocyclohexa-2,
    5-dien-1-ylidene)hydrazinyl]-2-hydroxybenzoic acid; Rasal; Olsalazinum; 5,5'-Azobis(salicylic acid);Dipentum;
  • CAS Registry Number:
  • Density: 1.55g/cm3
  • Refractive index: 1.678
  • Molecular Weight: 302.239
  • InchiKey: ULGVHUUBIHTFAM-PXNMLYILSA-N
  • InChI: InChI=1S/C14H10N2O6/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-
    8)14(21)22/h1-6,15,17H,(H,19,20)(H,21,22)/b16-8-
  • Molecular Formula: C14H10N2O6
  • Molecular Structure:CAS No:15722-48-2 5-[(2Z)-2-(3-carboxy-4-oxocyclohexa-2,<br />5-dien-1-ylidene)hydrazinyl]-2-hydroxybenzoic acid
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15722-48-2 Olsalazine

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15722-48-2 Olsalazine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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15722-48-2 Olsalazine

  • China ORCHID CHEMICAL SUPPLIES LTD (OCS) [Importer/Exporter]
  • Tel: +86-571-85395792
  • Fax: +86-571-85420103
  • Address: 607, North Zhongshan Road, Hangzhou 310000 China ,ZhejiangChina
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15722-48-2 Olsalazine

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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15722-48-2 Olsalazine

  • China HuaiBei SanHe Developing Co., Ltd. [Manufacturers]
  • Tel: 86-561-3191113
  • Fax: +86-561-3192253
  • Address: Room 201,Building ZY-1,GuCheng Road,Huaibei,Anhui,China ,anhuiChina
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15722-48-2 Olsalazine

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15722-48-2 OLSALAZINE SODIUM

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 ,Canada
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15722-48-2 Olsalazine

  • United States CBSCHEM LIMITED []
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 ,United States
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15722-48-2 Olsalazine

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References of 5-[(2Z)-2-(3-carboxy-4-oxocyclohexa-2,
5-dien-1-ylidene)hydrazinyl]-2-hydroxybenzoic acid
Title: Olsalazine
CAS Registry Number: 15722-48-2
CAS Name: 3,3¢-Azobis(6-hydroxybenzoic acid)
Synonyms: C.I. Mordant Yellow 5; 3,3¢-dicarboxy-4,4¢-dihydroxyazobenzene; 5,5¢-azobis(salicylic acid); azodisal
Molecular Formula: C14H10N2O6
Molecular Weight: 302.24
Percent Composition: C 55.63%, H 3.33%, N 9.27%, O 31.76%
Literature References: Dimer of mesalamine, q.v., originally used as a mordant dye. Prepn: DE 278613; C. Mettler, US 1157169 (1914, 1915 both to J. R. Geigy). Improved prepn: K. H. Agback, A. S. Nygren, EP 36636; eidem, US 4528367 (1981, 1985 both to Pharmacia AB). HPLC determn in biological samples: R. A. van Hogezand et al., J. Chromatogr. 305, 470 (1984). In vitro effect on fecal bacteria: H. Sandberg-Gertzen et al., Scand. J. Gastroenterol. 20, 607 (1985). Clinical pharmacokinetics and metabolism: C. P. Willoughby et al., Gut 23, 1081 (1982). Clinical trial in ulcerative colitis: H. Sandberg-Gertzen et al., Gastroenterology 90, 1024 (1986). Review of clinical experience in inflammatory bowel disease: A. N. Wadworth, A. Fitton, Drugs 41, 647-664 (1991).
 
Derivative Type: Disodium salt
CAS Registry Number: 6054-98-4
Synonyms: Azodisal sodium; disodium azodisalicylate; C.I. 14130
Manufacturers' Codes: CJ-91B
Trademarks: Dipentum (Pfizer)
Molecular Formula: C14H8N2Na2O6
Molecular Weight: 346.20
Percent Composition: C 48.57%, H 2.33%, N 8.09%, Na 13.28%, O 27.73%
Properties: Yellow crystalline powder, mp 240° (dec). Sol in water, DMSO. Practically insol in ethanol, chloroform, ether.
Melting point: mp 240° (dec)
 
Use: Mordant dye for wool.
Therap-Cat: Anti-inflammatory (gastrointestinal).
Keywords: Anti-inflammatory (Gastrointestinal); Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives.