CAS No 159138-80-4 , N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide Search by region : China

Name: N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide
Synonyms: Cariporide [INN]; HOE642;N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide; HOE 642; 159138-80-4; 4-isopropyl-3-(methylsulfonyl)benzoyl-guanidine methanesulfonate;
CAS Registry Number:159138-80-4
Flash Point: 282.1°C
Boiling Point: 542.8°Cat760mmHg
Density: 1.34g/cm³
Refractive index: 1.601
Flash Point: 282.1°C
Molecular Weight: 283.34668
InchiKey: IWXNYAIICFKCTM-UHFFFAOYSA-N
InChI: InChI=1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,
17)18/h4-7H,1-3H3,(H4,13,14,15,16)
Molecular Formula: C₁₂H₁₇N₃O₃S
Molecular Structure:

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159138-80-4 Cariporide

Cariporide, Min 99%
Finechemie Co., Ltd. [Manufacturer]
Tel: +86-23-99186710
Fax: +86-23-99186729
Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina

159138-80-4 CARIPORIDE

Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
Fax: +86 25 8345-3275
Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

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References of N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide

Title: Cariporide
CAS Registry Number: 159138-80-4
CAS Name: N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)benzamide
Synonyms: 4-isopropyl-3-(methanesulfonylbenzoyl)guanidine
Molecular Formula: C12H17N3O3S
Molecular Weight: 283.35
Percent Composition: C 50.87%, H 6.05%, N 14.83%, O 16.94%, S 11.32%
Literature References: Selective inhibitor of the sodium-hydrogen exchanger subtype 1 (NHE-1); protects against myocardial injury following ischemia and reperfusion. Prepn: H. J. Lang et al., EP 589336; eidem, US 5591754 (1994, 1997 both to Hoechst); A. Weichert et al., Arzneim.-Forsch. 47, 1204 (1997). Pharmacology: W. Scholz et al., Cardiovasc. Res. 29, 260 (1995). Symposium on pharmacology and clinical experience: Am. J. Cardiol. 83, Suppl. 10A, 1G-25G (1999). Review: W. Scholz et al., J. Thromb. Thrombolysis 8, 61-70 (1999).
Properties: Colorless solid, mp 90-94° (dec).
Melting point: mp 90-94° (dec)

Derivative Type: Methanesulfonate
CAS Registry Number: 159138-81-5
Synonyms: Cariporide mesylate
Manufacturers' Codes: HOE-642
Molecular Formula: C12H17N3O3S.CH3SO3H
Molecular Weight: 379.45
Percent Composition: C 41.15%, H 5.58%, N 11.07%, O 25.30%, S 16.90%
Properties: Colorless needles from isopropanol + water, mp 227-230°.
Melting point: mp 227-230°

Therap-Cat: Cardioprotective.
Keywords: Cardioprotective.