Home > Name List By n > N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide

CAS No 159138-80-4 , N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide

  • Name: N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide
  • Synonyms: Cariporide [INN]; HOE642;N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide; HOE 642; 159138-80-4; 4-isopropyl-3-(methylsulfonyl)benzoyl-guanidine methanesulfonate;
  • CAS Registry Number:
  • Flash Point: 282.1°C
  • Boiling Point: 542.8°Cat760mmHg
  • Density: 1.34g/cm3
  • Refractive index: 1.601
  • Flash Point: 282.1°C
  • Molecular Weight: 283.34668
  • InchiKey: IWXNYAIICFKCTM-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,
    17)18/h4-7H,1-3H3,(H4,13,14,15,16)
  • Molecular Formula: C12H17N3O3S
  • Molecular Structure:CAS No:159138-80-4 N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide

Related products

Search by region :

Select to

159138-80-4 CARIOGENIC TEST DIET MIT 200 RAT POWDERCARIPORIDE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

159138-80-4 Cariporide

  • Cariporide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

159138-80-4 CARIPORIDE

  • United States MINAKEM, L.L.C. [Manufacturer]
  • Tel: 201-225-9252/ + 33 3 20 64 68 40
  • Fax: 201-225-9253
  • Address: US Office:
    MINAKEM, L.L.C.
    411 Hackensack Avenue
    Continental Plaza ? 4th Floor
    Hackensack, New Jersey 07601 null,nullUnited States
Contact Supplier

159138-80-4 CARIPORIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide
Title: Cariporide
CAS Registry Number: 159138-80-4
CAS Name: N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)benzamide
Synonyms: 4-isopropyl-3-(methanesulfonylbenzoyl)guanidine
Molecular Formula: C12H17N3O3S
Molecular Weight: 283.35
Percent Composition: C 50.87%, H 6.05%, N 14.83%, O 16.94%, S 11.32%
Literature References: Selective inhibitor of the sodium-hydrogen exchanger subtype 1 (NHE-1); protects against myocardial injury following ischemia and reperfusion. Prepn: H. J. Lang et al., EP 589336; eidem, US 5591754 (1994, 1997 both to Hoechst); A. Weichert et al., Arzneim.-Forsch. 47, 1204 (1997). Pharmacology: W. Scholz et al., Cardiovasc. Res. 29, 260 (1995). Symposium on pharmacology and clinical experience: Am. J. Cardiol. 83, Suppl. 10A, 1G-25G (1999). Review: W. Scholz et al., J. Thromb. Thrombolysis 8, 61-70 (1999).
Properties: Colorless solid, mp 90-94° (dec).
Melting point: mp 90-94° (dec)
 
Derivative Type: Methanesulfonate
CAS Registry Number: 159138-81-5
Synonyms: Cariporide mesylate
Manufacturers' Codes: HOE-642
Molecular Formula: C12H17N3O3S.CH3SO3H
Molecular Weight: 379.45
Percent Composition: C 41.15%, H 5.58%, N 11.07%, O 25.30%, S 16.90%
Properties: Colorless needles from isopropanol + water, mp 227-230°.
Melting point: mp 227-230°
 
Therap-Cat: Cardioprotective.
Keywords: Cardioprotective.