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CAS No 162635-04-3 , Temsirolimus

  • Name: Temsirolimus
  • Synonyms: 42-(3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate)rapamycin;CCL-779; Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate;Rapamycin 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate;Temsirolimus;
  • CAS Registry Number:
  • Flash Point: 587.8°C
  • Boiling Point: 1048.4°Cat760mmHg
  • Density: 1.2g/cm3
  • Refractive index: 1.553
  • Flash Point: 587.8°C
  • Molecular Weight: 1030.29
  • InChI: InChI=1/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7)56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38(6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-44(47(28-40)69-10)72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50,58-59,62,67H,15-16,19-25,27-32H2,1-11H3/b14-12+,17-13+,34-18+,38-26+
  • Molecular Formula: C56H87NO16
  • Molecular Structure:CAS No:162635-04-3 Temsirolimus
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162635-04-3 Temsirolimus

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162635-04-3 Temsirolimus

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 ,China
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162635-04-3 Temsirolimus

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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162635-04-3 TEMSIROLIMUS

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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162635-04-3 Temsirolimus

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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162635-04-3 TEMSIROLIMUS

  • China Apichem Chemical Technology Co., Ltd [Manufacturer]
  • Tel: 86-137-6120-5405/ 86-21-3762-3285
  • Address: Apichem Chemical Technology Co., Ltd
    room 102, No.22,lane 288,
    Qianshao Road,
    Pudong, shanghai 201201 China ,China
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162635-04-3 Temsirolimus

  • China TaiZhou HiKong Chemical Co., Ltd. []
  • Tel: +86-18967213045,13957694715
  • Fax: +86-(580)-6033180,6034626
  • Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000, ,China
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  • China HANGZHOU ONICON CHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-571-85054016/ +86-571-85104679
  • Fax: +86-571-85054082
  • Address: HANGZHOU ONICON CHEMICAL CO.,LTD
    303-306 Hangzhou yiyao Building,
    No.439 Zhongshan North Rd.
    Hangzhou China
    Phone : +86-571-85054016
    Fax: +86-571-85054082
    E-Mail1: cjw9999@163.com ,China
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References of Temsirolimus
Title: Temsirolimus
CAS Registry Number: 162635-04-3
CAS Name: Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]
Synonyms: rapamycin 42-ester with 2,2-bis-(hydroxymethyl)propionic acid
Manufacturers' Codes: CCI-779
Molecular Formula: C56H87NO16
Molecular Weight: 1030.29
Percent Composition: C 65.28%, H 8.51%, N 1.36%, O 24.85%
Literature References: Ester analog of rapamycin, q.v.; selectively inhibits mammalian target of rapamycin (mTOR). Prepn: J. S. Skotnicki et al., US 5362718 (1994 to Am. Home Prod.). Lipase-catalyzed synthesis from rapamycin: J. Gu et al., Org. Lett. 7, 3945 (2005). Clinical pharmacology: E. Raymond et al., J. Clin. Oncol. 22, 2336 (2004). Clinical study in advanced refractory renal cell carcinoma: M. B. Atkins et al., ibid. 909. Clinical evaluation in glioblastoma multiforme: E. Galanis et al., J. Clin. Oncol. 23, 5294 (2005); in breast cancer: S. Chan et al., ibid. 5314; in mantle cell lymphoma: T. E. Witzig et al., ibid. 5347.
Properties: White solid. Sol in water. Lipophilic.
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antibiotics and Analogs.