Home > Name List By other > (3S)-3-[[(2S)-5-amino-5-oxo-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino] pentanoyl]amino]-4-[[(2S)-1-[[(2S, 3R)-1-[[2-[[(2S)-1...

CAS No 17650-98-5 , (3S)-3-[[(2S)-5-amino-5-oxo-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]
pentanoyl]amino]-4-[[(2S)-1-[[(2S,
3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-
phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-
methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-
yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-(4-
sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid

  • Name: (3S)-3-[[(2S)-5-amino-5-oxo-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]
    pentanoyl]amino]-4-[[(2S)-1-[[(2S,
    3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-
    phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-
    methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-
    yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-(4-
    sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid
  • Synonyms: CHEBI:59219; Ceruletidum [INN-Latin]; CCRIS 3063; 17650-98-5; Ceruletida;(3S)-3-[[(2S)-5-amino-5-oxo-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]
    pentanoyl]amino]-4-[[(2S)-1-[[(2S,
    3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-
    phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-
    methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-
    yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-(4-
    sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid; Ceruletida [INN-Spanish];Ceruletide; Cerulein; Ceruletidum;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.406g/cm3
  • Refractive index: 1.637
  • Safety Statements: A poison by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx and SOx.
  • Hazard Symbols: A poison.
  • Flash Point: °C
  • EINECS: 17650-98-5
  • Molecular Weight: 1352.40472
  • InchiKey: YRALAIOMGQZKOW-HYAOXDFASA-N
  • InChI: InChI=1S/C58H73N13O21S2/c1-29(72)49(71-57(87)40(23-31-12-14-33(15-13-31)
    92-94(89,
    90)91)68-56(86)43(26-48(78)79)69-52(82)37(16-18-44(59)73)65-51(81)36-17-
    19-45(74)63-36)58(88)62-28-46(75)64-41(24-32-27-61-35-11-7-6-10-34(32)
    35)54(84)66-38(20-21-93-2)53(83)70-42(25-47(76)77)55(85)67-39(50(60)80)
    22-30-8-4-3-5-9-30/h3-15,27,29,36-43,49,61,72H,16-26,28H2,1-2H3,(H2,59,
    73)(H2,60,80)(H,62,88)(H,63,74)(H,64,75)(H,65,81)(H,66,84)(H,67,85)(H,
    68,86)(H,69,82)(H,70,83)(H,71,87)(H,76,77)(H,78,79)(H,89,90,91)/t29-,
    36+,37+,38+,39+,40+,41+,42+,43+,49+/m1/s1
  • Molecular Formula: C58H73N13O21S2
  • Molecular Structure:CAS No:17650-98-5 (3S)-3-[[(2S)-5-amino-5-oxo-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]<br />pentanoyl]amino]-4-[[(2S)-1-[[(2S,<br />3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-<br />phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-<br />methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-<br />yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-(4-<br />sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid

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17650-98-5 CAERULEIN

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
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17650-98-5 330109 CAERULEIN PYR-GLN-ASP-TYR(SO3H)-THR-GLY-TRP-MET-ASP-PHE-NH2

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17650-98-5 CAERULEIN

  • United States American Peptide Company, Inc. [Manufacturer]
  • Tel: 800-926-8272/ 408-733-7604
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17650-98-5 Caerulein

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References of (3S)-3-[[(2S)-5-amino-5-oxo-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]
pentanoyl]amino]-4-[[(2S)-1-[[(2S,
3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-
phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-
methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-
yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-(4-
sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid
Title: Ceruletide
CAS Registry Number: 17650-98-5
CAS Name: Caerulein
Synonyms: cerulein
Manufacturers' Codes: FI-6934
Molecular Formula: C58H73N13O21S2
Molecular Weight: 1352.40
Percent Composition: C 51.51%, H 5.44%, N 13.46%, O 24.84%, S 4.74%
Literature References: Cholecystokinin analog; decapeptide discovered in the skins of Australian amphibians: V. Erspamer et al., Nature 212, 204 (1966). Isoln from Hyla caerulea and structure: A. Anastasi et al., Experientia 23, 699 (1967); eidem, Arch. Biochem. Biophys. 125, 57 (1968). Synthesis: L. Bernardi et al., Experientia 23, 700 (1967); eidem, ZA 6704716; eidem, US 3472832 (1968, 1969 to Soc. Farm. Italia). Shows hypotensive activity, stimulates smooth muscle and increases gastric, pancreatic, and biliary secretions: V. Erspamer et al., Experientia 23, 702 (1967). Series of articles on metabolism: Eur. J. Biochem. 91, 21-48 (1978). Pharmacodynamics: N. Iwatsuki, O. H. Petersen, J. Cell Biol. 79, 533 (1978); T. Fujita et al., Adv. Exp. Med. Biol. 106, 147 (1978). Diagnostic use: R. Fujita et al., Acta Gastroenterol. Belg. 40, 167 (1977); C. Monti et al., Radiology 129, 611 (1978). Toxicology: T. Chieli et al., Toxicol. Appl. Pharmacol. 23, 480 (1972). Reviews of pharmacology and clinical applications: G. Bertaccini, Pharmacol. Rev. 28, 127 (1976); and toxicology: M. E. Vincent et al., Pharmacotherapy 2, 223 (1982).
Properties: mp 224-226° (dec). [a]D20 -26° (c = 1 in DMF).
Melting point: mp 224-226° (dec)
Optical Rotation: [a]D20 -26° (c = 1 in DMF)
 
Derivative Type: Diethylamine salt
CAS Registry Number: 71247-25-1
Trademarks: Ceosunin (Kyowa); Takus (Montedison); Tymtran (Adria)
Properties: Off-white hygroscopic powder. Sol in DMF and DMSO. Insol in acetone, diethyl ether. LD50 i.v. in mice: 1012 mg/kg (Chieli).
Toxicity data: LD50 i.v. in mice: 1012 mg/kg (Chieli)
 
Therap-Cat: Stimulant (gastric secretory). Diagnostic aid (pancreatic function; cholecystokinetic agent in cholecystography).
Keywords: Diagnostic Aid; Gastric and Pancreatic Secretion Stimulant.