Home > Name List By 8 > 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propen-1-yl]-, methyl ester,(1R,2S,3S,5S)-

CAS No 180468-34-2 , 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propen-1-yl]-, methyl ester,(1R,2S,3S,5S)-

  • Name: 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propen-1-yl]-, methyl ester,(1R,2S,3S,5S)-
  • Synonyms: 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propen-1-yl]-, methyl ester,(1R,2S,3S,5S)-; Altropane;8-Azabicyclo[3.2.1]octane-2-carboxylic acid,3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propenyl]-, methyl ester, (1R,2S,3S,5S)-(9CI);8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-fluorophenyl)-8-(3-iodo-2-propenyl)-, methyl ester, [1R-[1a,2a,3a,5a,8(E)]]-;
  • CAS Registry Number:
  • Flash Point: 220.3°C
  • Boiling Point: 440.7°Cat760mmHg
  • Density: 1.498g/cm3
  • Refractive index: 1.586
  • Flash Point: 220.3°C
  • Molecular Weight: 0
  • InChI: InChI=1/C18H21FINO2/c1-23-18(22)17-15(12-3-5-13(19)6-4-12)11-14-7-8-16(17)21(14)10-2-9-20/h2-6,9,14-17H,7-8,10-11H2,1H3/b9-2+/t14-,15+,16+,17-/m0/s1
  • Molecular Formula: C18H21 F I N O2
  • Molecular Structure:CAS No:180468-34-2 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propen-1-yl]-, methyl ester,(1R,2S,3S,5S)-
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180468-34-2 4210 ALTROPANE

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References of 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propen-1-yl]-, methyl ester,(1R,2S,3S,5S)-
Title: IACFT
CAS Registry Number: 180468-34-2
CAS Name: (1R,2S,3S,5S)-3-(4-Fluorophenyl)-8-[(2E)-3-(iodo-2-propenyl)]-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Synonyms: 2b-carboxymethoxy-3b-(4-fluorophenyl)-N-(1-iodoprop-1-en-3-yl)nortropane
Trademarks: Altropane (Organix)
Molecular Formula: C18H21FINO2
Molecular Weight: 429.27
Percent Composition: C 50.36%, H 4.93%, F 4.43%, I 29.56%, N 3.26%, O 7.45%
Literature References: Cocaine analog with dopamine transport inhibitor activity. Radiolabeled form designed for SPECT brain imaging. Prepn: D. R. Elmaleh et al.,WO 9511901; eidem, US 5493026 (1995, 1996 both to Gen. Hosp. Corp., Harvard College, Organix and Northeastern Univ.); and receptor binding studies: eidem, J. Nucl. Med. 37, 1197 (1996). Series of articles on pharmacology and binding studies: B. K. Madras et al., Synapse 29, 93-127 (1998). Clinical evaluation in Parkinson's disease: A. J. Fischman et al., ibid. 128. CE determn in plasma: K. Hettiarachchi et al., J. Chromatogr. A 895, 87 (2000).
Properties: White solid, mp 115-116°,
Melting point: mp 115-116°,
 
Derivative Type: 123I-Labeled form
CAS Registry Number: 208517-65-1
 
Derivative Type: 125I-Labeled form
CAS Registry Number: 180268-78-4
 
Therap-Cat: 123I-labeled form as diagnostic aid (radioactive imaging agent).