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CAS No 198481-32-2 , 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol

  • Name: 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol
  • Synonyms: Bazedoxifeno;1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-;1-((4-(2-Hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol;Tse-424;Bazedoxifene [inn];Bazedoxifeno [inn-spanish];Bazedoxifene;1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol;
  • CAS Registry Number:
  • Flash Point: 373.8°C
  • Boiling Point: 694.4°C at 760 mmHg
  • Density: 1.19g/cm3
  • Refractive index: 1.622
  • Flash Point: 373.8°C
  • Molecular Weight: 0
  • InChI: InChI=1/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3
  • Molecular Formula: C30H34N2O3
  • Molecular Structure:CAS No:198481-32-2 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol
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198481-32-2 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol

  • Product Name: 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol;1-((4-(2-Hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol;1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)eth...
  • China Shanghai Send Pharmaceutical Technology Co., Ltd [Manufacturer]
  • Tel: 86-21-50266790
  • Fax: 86-21-50266790
  • Address: No.300 Chuantu Road Pudong District Shanghai,China Shanghai,ShanghaiChina
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198481-32-2 Bazedoxifen

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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198481-32-2 Bazedoxifene

  • Bazedoxifene, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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198481-32-2 Bazedoxifen

  • India Manus Aktteva null
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, null,nullIndia
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References of 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol
Title: Bazedoxifene
CAS Registry Number: 198481-32-2
CAS Name: 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-o1
Synonyms: 1-[4-(2-azepan-1-ylethoxy)benzyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol
Molecular Formula: C30H34N2O3
Molecular Weight: 470.60
Percent Composition: C 76.57%, H 7.28%, N 5.95%, O 10.20%
Literature References: Nonsteroidal selective estrogen receptor modulator (SERM). Prepn: C. P. Miller et al., EP 802183; eidem, US 5998402 (1997, 1999 both to American Home); C. P. Miller et al., J. Med. Chem. 44, 1654 (2001). Pharmacology and receptor binding study: B. S. Komm et al., Endocrinology 146, 3999 (2005). Clinical pharmacology: S. Ronkin et al., Obstet. Gynecol. 105, 1397 (2005). Review of development: B. S. Komm, C. R. Lyttle, Ann. N.Y. Acad. Sci. 949, 317-326 (2001); and therapeutic potential: C. Gruber, D. Gruber, Curr. Opin. Invest. Drugs 5, 1086-1093 (2004).
Properties: mp 98-102°.
Melting point: mp 98-102°
 
Derivative Type: Acetate
CAS Registry Number: 198481-33-3
Manufacturers' Codes: TSE-424; WAY-140424; WAY-TSE-424
Molecular Formula: C30H34N2O3.C2H4O2
Molecular Weight: 530.65
Percent Composition: C 72.43%, H 7.22%, N 5.28%, O 15.08%
Properties: Crystals from acetone + acetic acid, mp 174-178°.
Melting point: mp 174-178°
 
Therap-Cat: Antiosteoporotic.
Keywords: Antiosteoporotic; Selective Estrogen Receptor Modulator (SERM).