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CAS No 202409-33-4 , 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine

  • Name: 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
  • Synonyms: Arcoxia; MK 0663; Nucoxia; 202409-33-4; MK-663; Algix; Etoricoxibe; MK-0663; Tauxib;5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine;
  • CAS Registry Number:
  • Melting Point: 134-135 ºC
  • Density: 1.298 g/cm3
  • Refractive index: 1.6
  • Molecular Weight: 358.8419
  • InchiKey: MNJVRJDLRVPLFE-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-
    5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3
  • Molecular Formula: C18H15ClN2O2S
  • Molecular Structure:CAS No:202409-33-4 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
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202409-33-4 Etoricoxib

  • We manufacture and provide Etoricxib API for pharmaceutical study and R&D. CAS 202409-33-4 Welcome to inquire!
  • China Shanghai BociMed Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: 86-21-58950312
  • Fax: --
  • Address: Building 9, No.150, Cailun Road Shanghai ,China
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202409-33-4 Etoricoxib

  • Etoricoxib
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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202409-33-4 Etoricoxib(5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine

  • White to off-white powder "For stock products, please contact us to confirm the required quantity and quote, we will provide you with COA,NMR,HPLC and other relevant information. skype:chemlin1999 email:services@chemlin.com.cn qq:4009977050"
  • China Nanjing Chemlin Chemical Industrial Co.,Ltd [Manufacturer]
  • Tel: 86-025-83697070
  • Address: 902, Longyin Plaza, No.217 North Zhongshan Road, Nanjing,JiangsuChina
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202409-33-4 Etoricoxib

  • IUPAC NAME-5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]- 2,3'-bipyridine MOLECULAR FORMULA-C18H15ClN2O2S MOLAR MASS-358.842 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

202409-33-4 Parecoxib

  • IUPAC NAME-N-{[4-(5-methyl-3-phenylisoxazol-4-yl)phenyl] sulfonyl}propanamide MOLECULAR FORMULA-C19H18N2O4S MOLAR MASS-370.422 g/mol Parecoxib is a water soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union.
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

202409-33-4 Etoricoxib

  • Etoricoxib
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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202409-33-4 Etoricoxib

  • Etoricoxib, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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202409-33-4 ETORICOXIB

  • ETORICOXIB
  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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202409-33-4 Etoricoxib

  • Etoricoxib, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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202409-33-4 Etoricoxib

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References of 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
Title: Etoricoxib
CAS Registry Number: 202409-33-4
CAS Name: 5-Chloro-6¢-methyl-3-[4-(methylsulfonyl)phenyl]-2,3¢-bipyridine
Synonyms: 5-chloro-3-(4-methylsulfonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine
Manufacturers' Codes: MK-663; MK-0663
Trademarks: Arcoxia (Merck & Co.)
Molecular Formula: C18H15ClN2O2S
Molecular Weight: 358.84
Percent Composition: C 60.25%, H 4.21%, Cl 9.88%, N 7.81%, O 8.92%, S 8.94%
Literature References: Selective cyclooxygenase-2 (COX-2) inhibitor. Prepn: D. Dube et al., WO 9803484; eidem, US 5861419 (1998, 1999 both to Merck Frosst); R. W. Friesen et al., Bioorg. Med. Chem. Lett. 8, 2777 (1998). Practical synthesis: I. W. Davies et al., J. Org. Chem. 65, 8415 (2000). HPLC determn in urine and plasma: C. Z. Matthews et al., J. Chromatogr. B 751, 237 (2001). Pharmacology: D. Riendeau et al., J. Pharmacol. Exp. Ther. 296, 558 (2001); A. Dallob et al., J. Clin. Pharmacol. 43, 573 (2003). Clinical comparison with indomethacin in acute gouty arthritis: H. R. Schumacher, Jr. et al., Br. Med. J. 324, 1488 (2002). Clinical trial in rheumatoid arthritis: A. K. Matsumoto et al., J. Rheumatol. 29, 1623 (2002); in osteoarthritis: S. P. Curtis et al., BMC Musculoskel. Disord. 6, 58 (2005); in ankylosing spondylitis: D. van der Heijde et al., Arthritis Rheum. 52, 1205 (2005). Gastrointestinal safety profile in inflammatory bowel diseases: Y. El Miedany et al., Am. J. Gastroenterol. 101, 311 (2006). Review of pharmacology and clinical development: P. Patrignani et al., Expert Opin. Pharmacother. 4, 265-284 (2003).
Properties: White solid, mp 127-128°. pKa 4.5. uv max (acetonitrile-phosphate buffer): 238, 280 nm.
Melting point: mp 127-128°
pKa: pKa 4.5
Absorption maximum: uv max (acetonitrile-phosphate buffer): 238, 280 nm
Therap-Cat: Anti-inflammatory; analgesic.
Keywords: Anti-inflammatory (Nonsteroidal); Cyclooxygenase-2 Selective Inhibitor; Analgesic (Non-Narcotic).