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CAS No 22071-15-4 , 2-(3-benzoylphenyl)propanoic acid

  • Name: 2-(3-benzoylphenyl)propanoic acid
  • Synonyms: Capisten; Oruvail; Epatec; Alrheumun; Profenid; 22071-15-4;2-(3-benzoylphenyl)propanoic acid; Alrheumat; Actron;Orudis;
  • CAS Registry Number:
  • Transport: 25kgs
  • Density: 1.198 g/cm3
  • Water Solubility: Insoluble
  • Safety Statements: 26-45-36/37/39
  • Hazard Symbols: T: Toxic;
  • EINECS: 244-759-8
  • Molecular Weight: 254.28056
  • InchiKey: DKYWVDODHFEZIM-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-
    12/h2-11H,1H3,(H,18,19)
  • Risk Statements: R25;R36/37/38
  • Molecular Formula: C16H14O3
  • Molecular Structure:CAS No:22071-15-4 2-(3-benzoylphenyl)propanoic acid
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22071-15-4 Ketoprofen

  • Ketoprofen
  • China Inter-Chemical [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,nullChina
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22071-15-4; 22161-81-5 KETOPROFEN

  • China Tianjin Ruiji Chemical Trade Co., LTD. [Manufacturers]
  • Tel: +86-22-23708202,23708203
  • Fax: +86-22-23386569
  • Address: 1101-2-5 Haoriyuan,Heiniucheng road,Hexi district,Tianjin 300060,P.R.CHINA TIANJIN,TIANJINChina
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22071-15-4 Ketoprofen

  • China Zhongbei Northland Bio-Chem Industry Co., Ltd [Manufacturer, Trading Company]
  • Tel: +86-452-6197129
  • Fax: +86-452-6197939
  • Address: 5F, C Liandalijing Bulding,No 259 Xinjiang Road, Jianhua District, Qiqiha''er,HeilongjiangChina
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22071-15-4 Ketoprofen

  • China Forehigh Trade and Industry Co. Ltd. Hebei [Manufacturers]
  • Tel: +86-311-85882468 85896060 85812872
  • Fax: +86-311-85882085
  • Address: 4th ,Floor Shenxing Building, Zhaiying Street, Shijiazhuang, China null,nullChina
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22071-15-4; 22161-81-5 KETOPROFEN

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22071-15-4 Ketoprofen

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22071-15-4; 22161-81-5 Ketoprofen

  • China N-Techem International Co.Ltd. null
  • Fax: 86-574-56707080
  • Address: Room 803, B Building, LiYuanShangDu, 39#, 158 Lane, HuanCheng XiLu, Ningbo, Zhejiang, China null,nullChina
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22071-15-4; 22161-81-5 KETOPROFEN

  • China Maxpharm Group null
  • Fax: 86-27-85788237 85787941
  • Address: B-24AB, Qingnian Plaza, Wuhan, 430022, China null,nullChina
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22071-15-4; 22161-81-5 Ketoprofen

  • China EasternChem Company Limited [Manufacturers]
  • Tel: 86-510-85032271-801
  • Fax: +86-510-5032272
  • Address: Room 1101, YongFeng Building, 27,QingYang Road Wuxi, Jiangsu, 214023 China Wuxi,JiangsuChina
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22071-15-4 Ketoprofen

  • China Xiamen Kaijia Imp & Exp Co., Ltd. [Importer/Exporter]
  • Tel: 86-592-5602533
  • Fax: +86-592-5653685
  • Address: Room406 Luhui Building No. 65 Haitian Road Huli Xiamen,China. null,fujianChina
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References of 2-(3-benzoylphenyl)propanoic acid
Title: Ketoprofen
CAS Registry Number: 22071-15-4
CAS Name: 3-Benzoyl-a-methylbenzeneacetic acid
Synonyms: m-benzoylhydratropic acid; 2-(3-benzoylphenyl)propionic acid
Manufacturers' Codes: RP-19583
Trademarks: Alreumat (Bayer); Alrheumun (Bayer); Capisten (Kissei); Epatec (Nissan); Fastum (Menarini); Iso-K (San Carlo); Ketofen (Fort Dodge); Ketopron (Alcon); Menamin (RPR); Meprofen (AGIPS); Orudis (RPR); Oruvail (RPR); Profenid (RPR); Toprec (RPR); Toprek (RPR)
Molecular Formula: C16H14O3
Molecular Weight: 254.28
Percent Composition: C 75.57%, H 5.55%, O 18.88%
Literature References: Prepn: D. Farge et al., ZA 6800524; eidem, US 3641127 (1968, 1972 both to Rh?ne-Poulenc); G. A. Pinna et al., Farmaco Ed. Sci. 35, 684 (1980). Resolution of isomers: S. Rendic et al., Chimia 29, 170 (1975). Enantioselective synthesis and absolute configuration of (+)-form: G. Comisso et al., Gazz. Chim. Ital. 110, 123 (1980). Pharmacology of enantiomers: P. J. Hayball et al., Chirality 4, 484 (1992). HPLC determn in plasma: R. Lovlin et al., J. Chromatogr. B 679, 196 (1996). Toxicity data: K. Ueno et al., J. Med. Chem. 19, 941 (1976). Comprehensive description: G. G. Liversidge, Anal. Profiles Drug Subs. 10, 443-471 (1981). Review of pharmacokinetics: F. Jamali, D. R. Brocks, Clin. Pharmacokinet. 19, 197-217 (1990); of clinical experience: E. M. Veys, Scand. J. Rheumatol. Suppl. 90, 3-44 (1991).
Properties: Crystals from 6:20 benzene-petr ether, mp 94°. uv max (methanol): 255 nm (log e 4.33). Sol in ether, alc, acetone, chloroform, DMF, ethyl acetate. Slightly sol in water. LD50 orally in rats: 101 mg/kg (Ueno).
Melting point: mp 94°
Absorption maximum: uv max (methanol): 255 nm (log e 4.33)
Toxicity data: LD50 orally in rats: 101 mg/kg (Ueno)
 
Derivative Type: Lysine salt
CAS Registry Number: 57469-78-0
Trademarks: Artrosilene (Domp?
Molecular Formula: C16H14O3.C6H14N2O2
Molecular Weight: 400.47
Percent Composition: C 65.98%, H 7.05%, O 19.98%, N 7.00%
 
Derivative Type: (S)-(+)-Form tromethamine salt
CAS Registry Number: 156604-79-4
Synonyms: Dexketoprofen trometamol
Trademarks: Enantyum (Menarini); Keral (Menarini)
Molecular Formula: C16H14O3.C4H11NO3
Molecular Weight: 375.42
Percent Composition: C 63.99%, H 6.71%, O 25.57%, N 3.73%
Literature References: Prepn: G. Carganico et al., WO 9411332 (1994 to Menarini). Clinical trial: C. Gay et al., Clin. Drug Invest. 11, 320 (1996).
Properties: White crystalline solid from ethanol-ethyl acetate, mp 104.8-105.1°. [a]D20 -5.2° (c = 1.47 in methanol).
Melting point: mp 104.8-105.1°
Optical Rotation: [a]D20 -5.2° (c = 1.47 in methanol)
 
Therap-Cat: Anti-inflammatory; analgesic.
Therap-Cat-Vet: Anti-inflammatory; analgesic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives.