Home > Name List By 5 > 5-Aza-2'-deoxycytidine

CAS No 2353-33-5 , 5-Aza-2'-deoxycytidine

  • Name: 5-Aza-2'-deoxycytidine
  • Synonyms: 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin;2'-desoxy-5-azacytidine; 5-Aza-2'-deoxycytidine; Decitabine & its intermediates; Decitabine;5-Aza-2'-deoxycytidine; Decitabine & its intermediates (R&D); Decitabine intermediates;
  • CAS Registry Number:
  • Flash Point: 247.6 °C
  • Boiling Point: 485.8 °C at 760 mmHg
  • Density: 1.9 g/cm3
  • Refractive index: 1.779
  • Water Solubility: acetic acid/water (1:1): 50 mg/mL
  • Safety Statements: R22,R36/37/38,
  • Hazard Symbols: Xi:Irritant;
  • Flash Point: 247.6 °C
  • EINECS: 219-089-4
  • Molecular Weight: 228.2
  • InChI: InChI=1/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)
  • Risk Statements: S26,
  • Molecular Formula: C8H12N4O4
  • Molecular Structure:CAS No:2353-33-5 5-Aza-2'-deoxycytidine
Search by region :

Select to

2353-33-5 Decitabine

  • Decitabine can inhibit DNA methylation. More information please visit the website: http://www.creative-enzymes.com/product/Decitabine_2255.html
  • Min. Order: 10
  • United States Creative Enzymes [Manufacturer]
  • Tel: 1-516-6698109
  • Fax: 1-631-9388127
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
Contact Supplier

2353-33-5 5-Aza-2'-deoxycytidine

Contact Supplier

2353-33-5 5-Aza-2'-deoxycytidine

  • Product Name: 4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-on;4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-one;5-azadeoxycytidine;5-triazin-2(1h)-one,4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-3;2'-DEO...
  • China Shanghai Send Pharmaceutical Technology Co., Ltd [Manufacturer]
  • Tel: 86-21-50266790
  • Fax: 86-21-50266790
  • Address: No.300 Chuantu Road Pudong District Shanghai,China Shanghai,ShanghaiChina
Contact Supplier

2353-33-5 Decitabine

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
Contact Supplier

2353-33-5 5-Aza-2'-deoxycytidine

Contact Supplier

2353-33-5 Decitabine

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
Contact Supplier

2353-33-5 5-Aza-2'-deoxycytidine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
Contact Supplier

2353-33-5 A496 5-AZA-2''-DEOXY-D-CYTIDINE

  • United Kingdom Carbosynth Limited [Manufacturer]
  • Tel: +44 (0)1635 578444
  • Fax: +44 (0)1635 579444
  • Address: Carbosynth Limited
    8&9 Old Station Business Park
    Compton
    Berkshire
    RG20 6NE
    UK ,United Kingdom
Contact Supplier

2353-33-5 5-Aza-2'-deoxycytidine

  • 5-Aza-2'-deoxycytidine, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
Contact Supplier

2353-33-5 5-aza-2'-deoxycytidine

  • 5-aza-2'-deoxycytidine
  • China sales@credimate.com [Manufacturer]
  • Tel: +86 21 51872179
  • Fax: +86 21 51872179
  • Address: Room 2110, Tower 1, Changan Mansion, No. 1001 Changan Road200070 ShanghaiCHINA Shanghai,China
Contact Supplier

Select to

References of 5-Aza-2'-deoxycytidine
Title: Decitabine
CAS Registry Number: 2353-33-5
CAS Name: 4-Amino-1-(2-deoxy-b-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one
Synonyms: 5-aza-2¢-deoxycytidine
Manufacturers' Codes: NSC-127716
Trademarks: Dacogen (SuperGen)
Molecular Formula: C8H12N4O4
Molecular Weight: 228.21
Percent Composition: C 42.10%, H 5.30%, N 24.55%, O 28.04%
Literature References: Pyrimidine analog that inhibits DNA methylation and induces differentiation of leukemic cells. Prepn: J. Pliml, F. Sorm, Collect. Czech. Chem. Commun. 29, 2576 (1964); A. Piskala, F. Sorm, in Nucleic Acid Chemistry Part 1 (Wiley, New York, 1978) pp 443-449. Improved synthesis: J. Ben-Hattar, J. Jiricny, Nucleosides Nucleotides 6, 393 (1987). Chemical stability in soln: K.-T. Lin et al., J. Pharm. Sci. 70, 1228 (1981). HPLC determn in plasma: eidem, J. Chromatogr. 345, 162 (1985). Clinical trial in chronic myelogenous leukemia: H. M. Kantarjian et al., Cancer 98, 522 (2003). Review of pharmacology and mechanism of action: R. L. Momparler, Pharmacol. Ther. 30, 287-299 (1985); idem et al., Leukemia 11, Suppl. 1, 1-6 (1997); of clinical experience: B. T. Hennessy et al., Expert. Opin. Invest. Drugs 12, 1985-1993 (2003).
Properties: Crystals from methanol, mp 201-202° (dec). [a]D22 +68.5° (30 min) ? +57.8° (6 hr) (c = 0.5 in water). uv max (pH 7): 244 nm (log e 3.86). LD50 in mice (mg/kg): 190 i.p. (Momparler, 1985).
Melting point: mp 201-202° (dec)
Optical Rotation: [a]D22 +68.5° (30 min) ? +57.8° (6 hr) (c = 0.5 in water)
Absorption maximum: uv max (pH 7): 244 nm (log e 3.86)
Toxicity data: LD50 in mice (mg/kg): 190 i.p. (Momparler, 1985)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs.