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CAS No 251565-85-2 , (2S)-2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic
acid

  • Name: (2S)-2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic
    acid
  • Synonyms: (s)-2-ethoxy-3-(4-(2-(4-methylsulphonyloxyphenyl)ethoxy)phenyl)propanoic acid; AZ-242; AR-H039242XX;(2S)-2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic
    acid; 251565-85-2;Galida;
  • CAS Registry Number:
  • Density: 1.278 g/cm3
  • Refractive index: 1.565
  • Molecular Weight: 408.46536
  • InchiKey: CXGTZJYQWSUFET-IBGZPJMESA-N
  • InChI: InChI=1S/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-
    4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,
    22)/t19-/m0/s1
  • Molecular Formula: C20H24O7S
  • Molecular Structure:CAS No:251565-85-2 (2S)-2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic<br />acid

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251565-85-2 TESAGLITAZAR

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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251565-85-2 Benzenepropanoic acid, a-ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]-,(aS)-

  • China Astatech(Chengdu) Pharmaceutical Co.,Ltd. [Manufacturers]
  • Tel: +86-28-82666845
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  • Address: West Kelin Road Wenjiang Cross-Straits Technological Industry Park,Chengdu,Sichuan,P.R. China Chengdu,SichuanChina
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251565-85-2 TESAGLITAZAR ( (S)-ALPHA-ETHOXY-4-[2-[4-[(METHYLSULFONYL)OXY]PHENYL]ETHOXY]BENZENEPROPANOIC ACID )

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
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References of (2S)-2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic
acid
Title: Tesaglitazar
CAS Registry Number: 251565-85-2
CAS Name: (aS)-a-Ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]benzenepropanoic acid
Synonyms: (S)-2-ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
Manufacturers' Codes: AZ-242
Trademarks: Galida (AstraZeneca)
Molecular Formula: C20H24O7S
Molecular Weight: 408.47
Percent Composition: C 58.81%, H 5.92%, O 27.42%, S 7.85%
Literature References: Dual-acting peroxisome proliferator-activated receptor (PPAR) a and g agonist. Prepn: K. Andersson, WO 9962872 (1999 to Astra); idem, US 6258850 (2001 to AstraZeneca). Crystal structure in complex with the PPARa and PPARg ligand binding domains: P. Cronet et al., Structure 9, 699 (2001). Solid-phase extraction LC/MS/MS determn in plasma: H. Svennberg et al., J. Chromatogr. B 787, 231 (2003). Mechanism of action study: B. D. Hegarty et al., Endocrinology 145, 3158 (2004). Clinical pharmacokinetics: H. Ericsson et al., Drug Metab. Dispos. 32, 923 (2004). Clinical effects on lipid and glucose metabolism in hypertriglyceridaemia and abdominal obesity: B. Fagerberg et al., Diabetologia 48, 1716 (2005). Review of clinical development: N. Kamber, T. M. E. Davis, IDrugs 8, 927-935 (2005).
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic.