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CAS No 26171-23-3 , 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid

  • Name: 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid
  • Synonyms: Tolmetine [INN-French]; 26171-23-3; Tolmetina [DCIT]; Tolmetine; Tolmetino [INN-Spanish];Tolectin;2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid; Tolmetinum [INN-Latin];
  • CAS Registry Number:
  • Melting Point: 156 ºC
  • Density: 1.18 g/cm3
  • Refractive index: 1.589
  • Water Solubility: 222 MG/L
  • Safety Statements: Poison by ingestion. Moderately toxic by intraperitoneal and rectal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx. See also SODIUM TOLMETIN.
  • EINECS: 247-497-2
  • Molecular Weight: 257.2845
  • InchiKey: UPSPUYADGBWSHF-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)
    18/h3-8H,9H2,1-2H3,(H,17,18)
  • Molecular Formula: C15H15NO3
  • Molecular Structure:CAS No:26171-23-3 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid
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26171-23-3 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
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  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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26171-23-3 1H-Pyrrole-2-acetic acid, 1-methyl-5-(4-methylbenz...

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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26171-23-3 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
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  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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26171-23-3 Tolmetin

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26171-23-3 1-METHYL-5-P-TOLUOYLPYRROLE-2-ACETIC ACID

  • United States HBCChem, Inc. [Manufacturer]
  • Tel: 510-219-6317
  • Fax: 510-675-0318
  • Address: HBCChem, Inc.
    2189 Whipple Road
    Union City, CA 94587 ,United States
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26171-23-3 Tolmetin

  • United States CBSCHEM LIMITED []
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  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 ,United States
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26171-23-3 Tolmentin

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26171-23-3 (AG-1) TOLMETIN

  • China Pharmasi Chemicals Co.Ltd [Manufacturer]
  • Tel: +86-21-67752521
  • Fax: +86-21-57819315
  • Address: Pharmasi Chemicals Co.Ltd
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    songjiang,shanghai,china ,China
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26171-23-3 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-

  • China Hangzhou Hysen Pharma Co.,Ltd [Manufacturers]
  • Tel: 0571-89937472
  • Fax: 0571-89937386
  • Address: ROOM 808, C# Zi Jin PLAZA , NO. 701, Gu'Dun ROAD hangzhou,zhejiangChina
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26171-23-3 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-

  • China Tianjin Crest Pharmaceutical R&D Co., Ltd. [Manufacturers]
  • Tel: +86-22-66211386 13820015214
  • Fax: +86-22-66211386
  • Address: Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457 tianjin,tianjinChina
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References of 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid
Title: Tolmetin
CAS Registry Number: 26171-23-3
CAS Name: 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid
Synonyms: 1-methyl-5-p-toluoylpyrrole-2-acetic acid; 5-(p-toluoyl)-1-methylpyrrole-2-acetic acid
Manufacturers' Codes: McN-2559
Molecular Formula: C15H15NO3
Molecular Weight: 257.28
Percent Composition: C 70.03%, H 5.88%, N 5.44%, O 18.66%
Literature References: Prepn: Carson, FR 1574570 (1969 to McNeil Labs.), C.A. 72, 100498y (1969). Pharmacology: Carson et al., J. Med. Chem. 14, 646 (1971); S. Wong et al., J. Pharmacol. Exp. Ther. 185, 127 (1973). Review: S. Wong in Pharmacological and Biochemical Properties of Drug Substances vol. 1, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1977) pp 233-255. Review of pharmacology and therapeutic efficacy: R. N. Brogden et al., Drugs 15, 429-450 (1978).
Properties: Crystals from acetonitrile, mp 155-157° (dec).
Melting point: mp 155-157° (dec)
 
Derivative Type: Sodium salt dihydrate
CAS Registry Number: 64490-92-2
Manufacturers' Codes: McN-2559-21-98
Trademarks: Reutol (Errekappa); Tolectin (McNeil); Tolmene (Sigma-Tau)
Molecular Formula: C15H14NNaO3.2H2O
Molecular Weight: 315.30
Percent Composition: C 57.14%, H 5.75%, N 4.44%, Na 7.29%, O 25.37%
 
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives.