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CAS No 27848-84-6 , Nicergoline

  • Name: Nicergoline
  • Synonyms: 5-Bromonicotinic acid 10-methoxy-1,6-dimethylergoline-8-methyl ester;Nicergoline;-;
  • CAS Registry Number:
  • Transport: 1544
  • Density: 1.47 g/cm3
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 248-694-6
  • Molecular Weight: 484.39
  • InChI: InChI=1/C24H26BrN3O3/c1-27-13-17-8-21-24(30-3,19-5-4-6-20(27)22(17)19)9-15(12-28(21)2)14-31-23(29)16-7-18(25)11-26-10-16/h4-7,10-11,13,15,21H,8-9,12,14H2,1-3H3/t15-,21-,24+/m1/s1
  • Risk Statements: S36
  • Molecular Formula: C24H26BrN3O3
  • Molecular Structure:CAS No:27848-84-6 Nicergoline
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27848-84-6 nicergoline

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27848-84-6 nicergoline

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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27848-84-6 nicergoline

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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27848-84-6 nicergoline

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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27848-84-6 NICERGOLINE

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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27848-84-6 nicergoline

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
  • Fax: +86-21-58408291
  • Address: 1213 JunMin Road,Pudong,China ,China
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27848-84-6 nicergoline

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27848-84-6 Nicergoline

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27848-84-6 Nicergoline

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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27848-84-6 0604 NICERGOLINE

  • United States Tocris Bioscience [Manufacturer]
  • Tel: (800) 421-3701/ (636) 207-7651
  • Fax: (800) 483-1993 / (636) 207-7683
  • Address: Tocris Bioscience
    16144 Westwoods Business Park
    Ellisville, Missouri 63021
    USA ,United States
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References of Nicergoline
Title: Nicergoline
CAS Registry Number: 27848-84-6
CAS Name: (8b)-10-Methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester)
Synonyms: 1-methyllumilysergol 8-(5-bromonicotinate) 10-methyl ether; 4,6,6a,7,8,9,10,10a-octahydro-10aa-methoxy-4,7-dimethylindolo[4,3-fg]quinoline-9-methanol 5-bromonicotinate; 8b-[(5-bromonicotinoyloxy)methyl]-1,6-dimethyl-10a-methoxyergoline; nicotergoline; nimergoline; MNE
Manufacturers' Codes: FI-6714
Trademarks: Cergodum (Duncan); Circo-Maren (Krewel); Dilasenil (Celtia); Duracebrol (Durachemie); Ergotop (Kwizda); Ergobel (Hormosan); Memoq (Gecke); Nicergolent (Ramon); Sermion (Farmitalia); Vasospan (Exa)
Molecular Formula: C24H26BrN3O3
Molecular Weight: 484.39
Percent Composition: C 59.51%, H 5.41%, Br 16.50%, N 8.67%, O 9.91%
Literature References: Prepn: Bernardi et al., US 3228943; Temperilli, DE 2112273 (1966, 1971, both to Farmitalia); Arcari et al., Experientia 28, 819 (1972). Series of articles on pharmacology, clinical studies, tolerability: Arzneim.-Forsch. 29, 1213-1316 (1979). Toxicity study: B. W. Neumann, F. Lauschner, ibid. 1206. Hemodynamic effects in the dog: ibid. 31, 1693 (1981). Use in acute myocardial infarction with diastolic hypertension: E. Triulzi et al., Farmaco Ed. Prat. 36, 449 (1981).
Properties: mp 136-138°. LD50 in male mice, rats (mg/kg): 860, 2800 orally; 46, 43 i.v. (Neumann, Lauschner).
Melting point: mp 136-138°
Toxicity data: LD50 in male mice, rats (mg/kg): 860, 2800 orally; 46, 43 i.v. (Neumann, Lauschner)
Therap-Cat: Vasodilator (cerebral, peripheral).
Keywords: a-Adrenergic Blocker; Vasodilator (Cerebral); Vasodilator (Peripheral).