Home > Name List By 7 > 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3, 8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-car...

CAS No 303-45-7 , 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,
8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde

  • Name: 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,
    8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
  • Synonyms: (+-)-Gossypol; (+/-)-Gossypol; racemic-Gossypol; Pogosin;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,
    8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde;(-)-Gossypol; Tash 1; AT101; 303-45-7; (+)-Gossypol;
  • CAS Registry Number:
  • Melting Point: 181-183 C
  • Flash Point: 395.9 ºC
  • Boiling Point: 707.888 ºC at 760 mmHg
  • Density: 1.403 g/cm3
  • Water Solubility: Soluble to 25 mM in Ethanol and to 25 mM in DMSO
  • Safety Statements: R22;R40
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 395.9 ºC
  • Molecular Weight: 518.5544
  • InchiKey: QBKSWRVVCFFDOT-UHFFFAOYSA-N
  • InChI: InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29
    (19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,
    33-38H,1-6H3
  • Risk Statements: S22;S36
  • Molecular Formula: C30H30O8
  • Molecular Structure:CAS No:303-45-7 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,<br />8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
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303-45-7 Gossypol

  • Creative Enzymes uses its expertise in enzyme manufacturing to supply customers enzymes using for life science research and production of medicines, food, alcohol, beer, fruit juice, fabric, paper, leather goods, etc. We provide Gossypol More informa...
  • Min. Order: 10
  • United States Creative Enzymes [Manufacturer]
  • Tel: 1-516-6698109
  • Fax: 1-631-9388127
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
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303-45-7 Gossypol

  • IUPAC NAME-2,2′-bis-(Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) MOLECULAR FORMULA-C30H30O8 MOLAR MASS-518.563 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Plot No: 04, Mayur Park, Harsool Aurangabad,MaharashtraIndia

303-45-7 GOSSYPOL(P)

  • GOSSYPOL(P)Gossypol
  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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303-45-7 gossypol

  • gossypol
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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303-45-7 Gossypol

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303-45-7 Gossypol

  • Gossypol
  • United Kingdom Molekula Ltd [Manufacturer]
  • Tel: +44 1202 863000
  • Fax: +44 1202 863003
  • Address: Technology House Old Forge Road Ferndown Industrial Estate Wimborne Dorset Bh21 7RR ,United Kingdom
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303-45-7 GOSSYPOL

  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland ,Switzerland
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303-45-7 GOSSYPOL

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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303-45-7 Gossypol acetic acid

  • Gossypol acetic acid
  • Germany SYNCHEM Laborgemeinschaft OHG [Manufacturer]
  • Tel: +49 (0) 5662 40873-0
  • Fax: +49 (0) 5662 40873-20
  • Address: SYNCHEM Laborgemeinschaft OHG
    Dr. Jaeger & Dr. Drinkuth
    Am Kies 2
    D-34587 Felsberg / Altenburg, Germany ,Germany
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303-45-7 Gossypol, 99%

  • Gossypol, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,China
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References of 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,
8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
Title: Gossypol
CAS Registry Number: 303-45-7
CAS Name: 1,1¢,6,6¢,7,7¢-Hexahydroxy-3,3¢-dimethyl-5,5¢-bis(1-methylethyl)[2,2¢-binaphthalene]-8,8¢-dicarboxaldehyde
Synonyms: 2,2¢-bis[1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthalene]; 2,2¢-bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene]
Molecular Formula: C30H30O8
Molecular Weight: 518.55
Percent Composition: C 69.49%, H 5.83%, O 24.68%
Literature References: Yellow pigment found in cottonseed; functions as a natural insecticide in plants. Name derived from the botanical name of the cotton plant, Gossypium L., Malvaceae. Isoln: J. Longmore, J. Soc. Chem. Ind. 5, 200 (1886); L. Marchlewski, J. Prakt. Chem. 60, 84 (1899); K. N. Campbell et al., J. Am. Chem. Soc. 59, 1723 (1937). Structural studies: R. Adams et al., ibid. 60, 2193 (1938). Synthesis: Edwards, J. Am. Oil Chem. Soc. 47, 441 (1970). NMR studies: J. W. Jaroszewski et al., NMR Spectrosc. Drug Res. 26, 75 (1988). Vibrational CD structural studies: T. B. Freedman et al., Chirality 15, 196 (2003). Prepn of enantiomers: M. K. Dowd, ibid. 486. HPLC determn: G. B. Marcelle et al., J. Pharm. Sci. 73, 396 (1984). Metabolism studies: M. B. Abou-Donia et al., Lipids 5, 938 (1970). Mechanism of action study: C.-Y. G. Lee et al., Mol. Cell. Biochem. 47, 65 (1982). Structure-activity study in tumor cell lines: M. D. Shelley et al., Anti-Cancer Drugs 11, 209 (2000). Clinical evaluation in malignant glioma: P. Bushunow et al., J. Neuro-Oncol. 43, 79 (1999); in male contraception: E. M. Coutinho et al., Contraception 61, 61 (2000). Review of chemistry: R. Adams et al., Chem. Rev. 60, 555-574 (1960); of toxicity in livestock: S. E. Morgan, Vet. Clinics North Am.: Food Anim. Pract. 5, 251-262 (1989); of clinical pharmacology and use as a male contraceptive agent: D. Wu, Drugs 38, 333-341 (1989); E. M. Coutinho, Contraception 65, 259-263 (2002).
Properties: Exists in 3 tautomeric forms. Yellow crystals from ether, mp 184°; from chloroform, mp 199°; from ligroin, mp 214°. Light sensitive. Very sol in methanol, ethanol, cold dioxane, diethylene glycol, ether, ethyl acetate, acetone, carbon tetrachloride, pyridine, chloroform, DMF, lipids. Freely sol (with slow decompn) in dil aq solns of ammonia and sodium carbonate. Slightly sol in glycerol, cyclohexane. Insol in water. Absorption max: 385 nm (e 18000).
Melting point: mp 184°; mp 199°; mp 214°
Absorption maximum: Absorption max: 385 nm (e 18000)
 
Derivative Type: R-Form
CAS Registry Number: 90141-22-3
Synonyms: (-)-gossypol
Properties: Bright yellow crystals from acetone, mp 181-184° (dec). [a]D28 -386 to -390° (c = 0.5 g/100 g soln in CHCl3) (Dowd).
Melting point: mp 181-184°
Optical Rotation: [a]D28 -386 to -390° (c = 0.5 g/100 g soln in CHCl3)
 
Derivative Type: S-Form
CAS Registry Number: 20300-26-9
Synonyms: (+)-gossypol
Literature References: Isoln from Thespesia populnea: T. J. King, L. B. de Silva, Tetrahedron Lett. 9, 261 (1968); S. C. Datta et al., Indian J. Chem. 10, 263 (1972). Synthesis: A. I. Meyers, J. J. Willemsen, Tetrahedron 54, 10493 (1998).
Properties: Bright yellow crystals from acetone, mp 181-184° (dec). [a]D28 +386 to +390° (c = 0.5 g/100 g soln in CHCl3) (Dowd). uv max (ethanol): 237.5, 277. 378 nm (log e 4.8, 4.4, 4.2) (Datta).
Melting point: mp 181-184°
Optical Rotation: [a]D28 +386 to +390° (c = 0.5 g/100 g soln in CHCl3)
Absorption maximum: uv max (ethanol): 237.5, 277. 378 nm (log e 4.8, 4.4, 4.2) (Datta).
 
Derivative Type: Gossypol Acetic Acid
CAS Registry Number: 12542-36-8
Properties: Bright yellow plates, mp 187° (Adams et al.).
Melting point: mp 187°
 
CAUTION: Potentially toxic to animals overfed cottonseed products; symptoms of overexposure may include cardiac failure, shortness of breath, pulmonary edema, and reproductive effects (Morgan).