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CAS No 304-21-2 , 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole

  • Name: 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole
  • Synonyms: O-Methylharmalol; 304-21-2; Harmine; Harmidine; Armalin;7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole; dihydro-;Dihydroharmine; 3,4-Dihydroharmine; Harmalol methyl ether;
  • CAS Registry Number:
  • Transport: 1544
  • Melting Point: 232-234 ºC
  • Density: 1.25 g/cm3
  • Refractive index: 1.647
  • Safety Statements: 22-24/25
  • Hazard Symbols: Xn
  • EINECS: 206-152-6
  • Molecular Weight: 214.26306
  • InchiKey: QJOZJXNKVMFAET-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,
    7,14H,5-6H2,1-2H3
  • Risk Statements: S22;S24/25
  • Molecular Formula: C13H14N2O
  • Molecular Structure:CAS No:304-21-2 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole
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304-21-2 Harmaline hydrochloride dihydrate

  • Harmaline hydrochloride dihydrate
  • United States INDOFINE Chemical Co., Inc. [Manufacturer]
  • Tel: (908) 359-6778
  • Fax: (908) 359-1179
  • Address: 121 Stryker Lane
    Bldg 30, Suite 1
    Hillsborough, NJ 08844 ,United States
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304-21-2 Harmaline

  • Harmaline
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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304-21-2 3,4-Dihydroharmin

  • China Shanghai Hanhong Chemical Co., Ltd. [, Manufacturer, Trading Company, Agent]
  • Tel: +86-(21)-64762736, 64531573
  • Fax: +86-(21)-54291107
  • Address: 206-209, NO.1 Building , NO.245,Jiachuan Road, Xuhui District, Shanghai, Xuhui District,ShanghaiChina
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304-21-2 HARMALINE HCL(RG)

  • HARMALINE HCL(RG)3,4-Dihydroharmin
  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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304-21-2 Harmaline hydrochloride dihydrate

  • Harmaline hydrochloride dihydrate3,4-Dihydro-7-methoxy-1-methyl-beta-carboline hydrochloride; Harmalol methyl ether hydrochloride; 3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]-indole hydrochloride
  • Switzerland Biosynth AG [Manufacturer]
  • Tel: +41 71 858 20 20/ 630.305.8400 (USA)
  • Fax: +41 71 858 20 30
  • Address: BIOSYNTH AG
    Rietlistrasse 4
    9422 Staad / Switzerland
    Phone: +41 (0)71 858 20 20
    Fax: +41 (0)71 858 20 30 ,Switzerland
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304-21-2 Harmaline

  • Harmaline, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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304-21-2 Harmaline

  • Harmaline, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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304-21-2 Harmaline hydrochloride

  • Harmaline hydrochlorideDihydroharmine hydrochloride
  • China Beijing HuameiHuli Biochem Ltd [Manufacturers]
  • Tel: 010-86181995
  • Fax: 010-86860610
  • Address: Beijing TongZhou District Beijing,BeijingChina
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304-21-2 3H-Pyrido[3,4-b]indole,4,9-dihydro-7-methoxy-1-methyl-

  • China BioBioPha Co., Ltd. [Manufacturer]
  • Tel: +86-871-5217109
  • Fax: +86-871-5217109
  • Address: 132 Lanhei Road, Kunming Institute of Botany, Chinese Academy of Sciences ,China
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304-21-2 Harmaline, 99%

  • Harmaline, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,China
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References of 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole
Title: Harmaline
CAS Registry Number: 304-21-2
CAS Name: 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole
Synonyms: 1-methyl-7-methoxy-3,4-dihydro-b-carboline; 3,4-dihydroharmine; harmidine; harmalol methyl ether; O-methylharmalol
Molecular Formula: C13H14N2O
Molecular Weight: 214.26
Percent Composition: C 72.87%, H 6.59%, N 13.07%, O 7.47%
Literature References: CNS stimulant from seeds of Peganum harmala L., Zygophyllaceae: Goebel, Ann. 38, 363 (1841); from Banisteria caapi Spruce, Malpighiaceae: Hochstein, Paradies, J. Am. Chem. Soc. 79, 5735 (1957). Structure: Manske et al., J. Chem. Soc. 1927, 1. Synthesis: Sp?th, Lederer, Ber. 63, 120, 2102 (1930); Spenser, Can. J. Chem. 37, 1851 (1959). Identity with harmidine: Robinson, Chem. Ind. (London) 1965, 605. Pharmacology: Fuentes, Longo, Neuropharmacology 10, 15 (1971). Metabolism: Ho et al., Biochem. Pharmacol. 20, 1313 (1971). Review of structure and synthesis work: Hofmann, Sven. Farm. Tidskr. 75, 933 (1971), C.A. 76, 149609g (1972).
Properties: Orthorhombic bipyramidal prisms, tablets from methanol, rhombic octahedra from ethanol, mp 229-231°. Solns fluoresce blue. pK 4.2. uv max (methanol): 218, 260, 376 nm (log e 4.27, 3.90, 4.02). Slightly sol in water, alcohol, ether; quite sol in hot alcohol, dil acids.
Melting point: mp 229-231°
pKa: pK 4.2
Absorption maximum: uv max (methanol): 218, 260, 376 nm (log e 4.27, 3.90, 4.02)
 
Derivative Type: Hydrochloride dihydrate
Properties: Slender, yellow needles, moderately sol in water, alcohol.
 
Derivative Type: N-Acetylharmaline
Properties: Needles, mp 204-205°.
Melting point: mp 204-205°