Home > Name List By 1 > 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1, 3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea

CAS No 33342-05-1 , 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,
3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea

  • Name: 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,
    3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea
  • Synonyms: Gliquidonum [INN-Latin]; Gliquidonum; Beglynor; 33342-05-1;Glurenorm;1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,
    3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea; Beglynora; Gliquidona; glycvidon; glikvidon;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.34 g/cm3
  • Refractive index: 1.624
  • Safety Statements: Low toxicity by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx and SOx.
  • Hazard Symbols: Low toxicity by ingestion. A reproductive hazard.
  • Flash Point: °C
  • EINECS: 251-463-2
  • Molecular Weight: 527.63242
  • InchiKey: LLJFMFZYVVLQKT-UHFFFAOYSA-N
  • InChI: InChI=1S/C27H33N3O6S/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)
    32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,
    17,19H,4-8,15-16H2,1-3H3,(H2,28,29,33)
  • Molecular Formula: C27H33N3O6S
  • Molecular Structure:CAS No:33342-05-1 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,<br />3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea

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References of 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,
3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea
Title: Gliquidone
CAS Registry Number: 33342-05-1
CAS Name: N-[(Cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide
Synonyms: 1-cyclohexyl-3-[[p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]phenyl]sulfonyl]urea; 1,2,3,4-tetrahydro-2-[p-(N￠-cyclohexylureido-N-sulfonyl)phenethyl]-4,4-dimethyl-7-methoxyisoquinoline-1,3-dione
Manufacturers' Codes: AR-DF 26
Trademarks: Glurenorm (Thomae)
Molecular Formula: C27H33N3O6S
Molecular Weight: 527.63
Percent Composition: C 61.46%, H 6.30%, N 7.96%, O 18.19%, S 6.08%
Literature References: Prepn: E. Kutter et al., DE 2000339 (1971 to Thomae); eidem, US 3708486 (1973 to Boehringer, Ing.); eidem, DE 2011126 (1971 to Thomae), C.A. 76, 14359e (1972). Pharmacokinetics and metabolism: Kopitar, Arzneim.-Forsch. 25, 1455 (1975); Kopitar et al., ibid. 1933.
Properties: Crystals from boiling methanol, mp 180-182°.
Melting point: mp 180-182°
 
Derivative Type: Sodium salt
Properties: Sinters at 160°. LD50 in mice: >2 g/kg orally; 234 mg/kg i.v. (Kutter, 1973).
Toxicity data: LD50 in mice: >2 g/kg orally; 234 mg/kg i.v. (Kutter, 1973)
 
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Sulfonylurea Derivatives.