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CAS No 34031-32-8 , AURANOFIN

  • Name: AURANOFIN
  • Synonyms: AURANOFIN;(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate;
  • CAS Registry Number:
  • Melting Point: 103 - 105
  • Flash Point: 298°C
  • Boiling Point: 425.5°Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Poison by ingestion, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: ulceration or bleeding from stomach. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and POx. See also GOLD COMPOUNDS.
  • Flash Point: 298°C
  • EINECS: 251-801-9
  • Molecular Weight: 678.48
  • InChI: InChI=1/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1/rC20H34AuO9PS/c1-8-31(9-2,10-3)21-32-20-19(29-15(7)25)18(28-14(6)24)17(27-13(5)23)16(30-20)11-26-12(4)22/h16-20H,8-11H2,1-7H3/t16-,17-,18+,19-,20+/m1/s1
  • Molecular Formula: C20H34AuO9PS
  • Molecular Structure:CAS No:34031-32-8 AURANOFIN
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34031-32-8 Auranofin

  • IUPAC NAME-gold(+1) cation; 3,4,5-triacetyloxy-6- (acetyloxymethyl) oxane-2-thiolate; triethylphosphanium MOLECULAR FORMULA-C20H35AuO9PS+ MOLAR MASS-679.493 g/mol Auranofin is used to treat rheumatoid arthritis. It improves arthritis symptoms includi...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

34031-32-8 Auranofin

  • Auranofin
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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34031-32-8 A495 AURANOFIN

  • United Kingdom Carbosynth Limited [Manufacturer]
  • Tel: +44 (0)1635 578444
  • Fax: +44 (0)1635 579444
  • Address: Carbosynth Limited
    8&9 Old Station Business Park
    Compton
    Berkshire
    RG20 6NE
    UK ,United Kingdom
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34031-32-8 Auranofine

  • Auranofine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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34031-32-8 Auranofin

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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34031-32-8 Auranofin

  • China Hangzhou Sage Chemical Co., Ltd. [, Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, ,ZhejiangChina
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34031-32-8 Auranofin

  • China Haihang Industry Co., Ltd. []
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, ,China
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34031-32-8 Auranofin

  • China China Langchem Inc. []
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, ,China
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34031-32-8 Auranofin

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34031-32-8 Auranofin

  • India Manus Aktteva []
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, ,India
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References of AURANOFIN
Title: Auranofin
CAS Registry Number: 34031-32-8
CAS Name: (1-Thio-b-D-glucopyranose-2,3,4,6-tetraacetato-S)(triethylphosphine)gold
Synonyms: (2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranosato-S)(triethylphosphine)gold; (1-thio-b-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
Manufacturers' Codes: SKF-39162
Trademarks: Crisinor (Rubio); Crisofin (Allergan); Ridaura (Prometheus); Ridauran (Robapharm)
Molecular Formula: C20H34AuO9PS
Molecular Weight: 678.48
Percent Composition: C 35.40%, H 5.05%, Au 29.03%, O 21.22%, P 4.57%, S 4.73%
Literature References: Disease modifying antirheumatic drug (DMARD); orally active gold coordination complex. Prepn: E. R. McGusty, B. M. Sutton, DE 2051495; eidem, US 3635945 (1971, 1972 both to SKF). Toxicity study: B. H. Payne, D. T. Walz, Vet. Pathol. 15, Suppl. 5, 1 (1978). HPLC determn in urine: R. Kizu et al., Chem. Pharm. Bull. 41, 1261 (1993). Symposium on pharmacology and clinical experience: J. Rheumatol. 9, Suppl. 8, 1-209 (1982). Clinical trial in rheumatoid arthritis: M. Itokazu et al., Clin. Ther. 17, 60 (1995); in steroid-dependent asthma: I. L. Bernstein et al., J. Allergy Clin. Immunol. 98, 317 (1996). Review: W. F. Kean et al., Br. J. Rheumatol. 36, 560-572 (1997).
Properties: White, odorless, crystalline powder, mp 112-115°. Insol in water. Unstable to light and heat. LD50 in rats, mice (mg/kg): 265, 310 orally (Payne, Walz).
Melting point: mp 112-115°
Toxicity data: LD50 in rats, mice (mg/kg): 265, 310 orally (Payne, Walz)
Therap-Cat: Antirheumatic.
Keywords: Antiarthritic/Antirheumatic.