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CAS No 35941-65-2 , butriptyline

  • Name: butriptyline
  • Synonyms: Butriptylene;10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine;butriptyline;3-(10,11-Dihydro-5H-dibenzo[A,D][7]annulen-5-yl)-N,N,2-trimethylpropan-1-amine;10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine;
  • CAS Registry Number:
  • Transport: 1851
  • Safety Statements: An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
  • Molecular Weight: 0
  • InChI: InChI=1/C21H27N/c1-16(15-22(2)3)14-21-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)21/h4-11,16,21H,12-15H2,1-3H3
  • Molecular Formula: C21H27N
  • Molecular Structure:CAS No:35941-65-2 butriptyline

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35941-65-2 BUTRIPTYLINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
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35941-65-2 BUTRIPTYLINE ( 10,11-DIHYDRO-NN -TRIMETHYL-5H-DIBENZO[A,D]CYCLOHEPTENE-5-PROPANAMINE )

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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References of butriptyline
Title: Butriptyline
CAS Registry Number: 35941-65-2
CAS Name: 10,11-Dihydro-N,N,b-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine
Synonyms: 5-(3-dimethylamino-2-methylpropyl)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; 5-(2-methyl-3-dimethylaminopropyl)dibenzo[a,d][1,4]cycloheptadiene; butriptylene
Molecular Formula: C21H27N
Molecular Weight: 293.45
Percent Composition: C 85.95%, H 9.27%, N 4.77%
Literature References: Prepn: Winthrop, Davis, BE 613750 (1962 to Ayerst, McKenna & Harrison), C.A. 57, 15036c (1962); eidem, J. Org. Chem. 27, 230 (1962); Villani, US 3409640 (1968 to Schering). Review of pharmacology and clinical data: see J. Med. 2, 249-343 (1971). Metabolic studies: Cameron et al., Arzneim.-Forsch. 24, 93 (1974). Toxicity: Voith, Herr, Arch. Int. Pharmacodyn. Ther. 182, 318 (1969).
Properties: Oil, bp1 180-185°.
Boiling point: bp1 180-185°
 
Derivative Type: Hydrochloride
CAS Registry Number: 5585-73-9
Manufacturers' Codes: AY-62014
Trademarks: Evadene (Ayerst); Evadyne (Ayerst)
Molecular Formula: C21H27N.HCl
Molecular Weight: 329.91
Percent Composition: C 76.45%, H 8.55%, N 4.25%, Cl 10.75%
Properties: Crystals from isopropyl alcohol-ether, mp 188-190° (dec). uv max (methanol): 273, 270, 266 nm (e 460, 441, 552). Freely sol in water; moderately sol in aliphatic alc, chloroform. Insol in ether, paraffinic hydrocarbons. LD50 in mice (mg/kg): 120 i.p.; 345 orally (Voith, Herr).
Melting point: mp 188-190° (dec)
Absorption maximum: uv max (methanol): 273, 270, 266 nm (e 460, 441, 552)
Toxicity data: LD50 in mice (mg/kg): 120 i.p.; 345 orally (Voith, Herr)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.