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CAS No 4394-00-7 , 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid

  • Name: 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
  • Synonyms: 4394-00-7; Landruma; Nifluminic acid; Donalgin; Niflam;Nifluril; Actol; Niflumate; Forenol;2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 203-204 ºC
  • Flash Point: 182
  • Boiling Point:
  • Density: 1.449 g/cm3
  • Water Solubility: insoluble
  • Safety Statements: R20/21/22;R36/37/38
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 182
  • EINECS: 224-516-2
  • Molecular Weight: 282.21797
  • InchiKey: JZFPYUNJRRFVQU-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H9F3N2O2/c14-13(15,
    16)8-3-1-4-9(7-8)18-11-10(12(19)20)5-2-6-17-11/h1-7H,(H,17,18)(H,19,20)
  • Risk Statements: S26;S36/37/39
  • Molecular Formula: C13H9F3N2O2
  • Molecular Structure:CAS No:4394-00-7 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
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4394-00-7 Niflumic acid

  • China Ningbo Medicn Pharmaceutical Co., Ltd [Manufacturer, Trading Company]
  • Tel: 86-574-56171709
  • Fax: --
  • Address: B708, Zhongshan Yin Zuo, 579#, Zhongshan East Road, Ningbo(315040), China ningbo,ZhejiangChina
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4394-00-7 Niflumic acid

  • Niflumic acid B20839 4394-00-7
  • China bepharm ltd. null
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China null,nullChina
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4394-00-7 Niflumic Acid

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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4394-00-7 Niflumic Acid

  • China Xilin Chemical Group Co., Ltd null
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, null,nullChina
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4394-00-7 NIFLUMIC ACID

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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4394-00-7 NIFLUMIC ACID

  • Germany Archimica [Manufacturer]
  • Tel: +49 (0)69 / 305-25866
  • Fax: +49 (0)69 / 305-17562
  • Address: Archimica
    Industriepark Hoechst, D 569
    65926 Frankfurt/Main, Germany null,nullGermany
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4394-00-7 Niflumic acid

  • China VETCHEM Biochemistry Science [Manufacturer, Distributor/Wholesaler]
  • Tel: +86-21-593837
  • Address: No.2 Jinshanwei Industrial Zon,Shanghai 200120 China Shanghai,ShanghaiChina
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4394-00-7 Niflumic acid

  • China KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: +86-23-8650081
  • Fax: +86-23-8650081
  • Address: 7F,Commercial Building, No.3 Nanping West Road,Nan null,nullChina
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4394-00-7 Niflumic Acid

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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4394-00-7 NIFLUMIC ACID

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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References of 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
Title: Niflumic Acid
CAS Registry Number: 4394-00-7
CAS Name: 2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid
Synonyms: 2-(a,a,a-trifluoro-m-toluidino)nicotinic acid; 2-[3-(trifluoromethyl)anilino]nicotinic acid
Manufacturers' Codes: UP-83
Trademarks: Actol (Fournier); Forenol (Roemmers); Landruma (Landerln); Nifluril
Molecular Formula: C13H9F3N2O2
Molecular Weight: 282.22
Percent Composition: C 55.33%, H 3.21%, F 20.20%, N 9.93%, O 11.34%
Literature References: Prepn: NL 6414717; C. Hoffmann, A. Faure, US 3415834 (1965, 1968 both to Lab. U.P.S.A.); eidem, Bull. Soc. Chim. Fr. 1966, 2316. Pharmacological and metabolic studies: Glasson et al., Biochem. Pharmacol. 18, 633 (1969); Boissier et al., Therapie 26, 211 (1971). Toxicity data: J. R. J. Sorenson, J. Med. Chem. 19, 135 (1976). Determn in human plasma by GLC: G. Houin et al., J. Chromatogr. 223, 351 (1981).
Properties: Crystals from ethanol, mp 204°. LD50 in rats (mg/kg): 370 orally; 155 i.p. (Sorenson).
Melting point: mp 204°
Toxicity data: LD50 in rats (mg/kg): 370 orally; 155 i.p. (Sorenson)
 
Derivative Type: b-Morpholinoethyl ester
CAS Registry Number: 65847-85-0
Synonyms: Morniflumate
Trademarks: Flomax (Chiesi); Nifluril (suppositories) (UPSA)
Molecular Formula: C19H20F3N3O3
Molecular Weight: 395.38
Percent Composition: C 57.72%, H 5.10%, F 14.42%, N 10.63%, O 12.14%
Literature References: Prepn of the ester HCl: Hoffmann, DE 1802777; idem, US 3708481 (1969, 1973 both to Hexachimie).
 
Derivative Type: Phthalidyl ester see Talniflumate
 
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Aminoarylcarboxylic Acid Derivatives.